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Adenoma of small intestine

MedGen UID:
226995
Concept ID:
C1302392
Neoplastic Process
Synonyms: Adenoma of Small Bowel; adenoma of small bowel; Adenoma of Small Intestine; adenoma of small intestine; Adenoma of the Small Bowel; adenoma of the small bowel; Adenoma of the Small Intestine; adenoma of the small intestine; Non-Ampullary Adenoma; Small Bowel Adenoma; small bowel adenoma; Small Intestinal Adenoma; small intestinal adenoma; small intestine adenoma
SNOMED CT: Adenoma of small intestine (399422005)
 
Monarch Initiative: MONDO:0021303

Definition

A neoplasm that arises from the glandular epithelium of the small intestine. It is a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous. [from NCI]

Professional guidelines

PubMed

Lucaciu L, Yano T, Saurin JC
Best Pract Res Clin Gastroenterol 2023 Jun-Aug;64-65:101852. Epub 2023 Jul 22 doi: 10.1016/j.bpg.2023.101852. PMID: 37652652
Kiran RP, Kochhar GS, Kariv R, Rex DK, Sugita A, Rubin DT, Navaneethan U, Hull TL, Ko HM, Liu X, Kachnic LA, Strong S, Iacucci M, Bemelman W, Fleshner P, Safyan RA, Kotze PG, D'Hoore A, Faiz O, Lo S, Ashburn JH, Spinelli A, Bernstein CN, Kane SV, Cross RK, Schairer J, McCormick JT, Farraye FA, Chang S, Scherl EJ, Schwartz DA, Bruining DH, Philpott J, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sandborn WJ, Silverberg MS, Pardi DS, Church JM, Shen B
Lancet Gastroenterol Hepatol 2022 Sep;7(9):871-893. Epub 2022 Jul 5 doi: 10.1016/S2468-1253(22)00039-5. PMID: 35798022
Vanbiervliet G, Strijker M, Arvanitakis M, Aelvoet A, Arnelo U, Beyna T, Busch O, Deprez PH, Kunovsky L, Larghi A, Manes G, Moss A, Napoleon B, Nayar M, Pérez-Cuadrado-Robles E, Seewald S, Barthet M, van Hooft JE
Endoscopy 2021 Apr;53(4):429-448. Epub 2021 Mar 16 doi: 10.1055/a-1397-3198. PMID: 33728632

Recent clinical studies

Etiology

Kiran RP, Kochhar GS, Kariv R, Rex DK, Sugita A, Rubin DT, Navaneethan U, Hull TL, Ko HM, Liu X, Kachnic LA, Strong S, Iacucci M, Bemelman W, Fleshner P, Safyan RA, Kotze PG, D'Hoore A, Faiz O, Lo S, Ashburn JH, Spinelli A, Bernstein CN, Kane SV, Cross RK, Schairer J, McCormick JT, Farraye FA, Chang S, Scherl EJ, Schwartz DA, Bruining DH, Philpott J, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sandborn WJ, Silverberg MS, Pardi DS, Church JM, Shen B
Lancet Gastroenterol Hepatol 2022 Sep;7(9):871-893. Epub 2022 Jul 5 doi: 10.1016/S2468-1253(22)00039-5. PMID: 35798022
Vanbiervliet G, Strijker M, Arvanitakis M, Aelvoet A, Arnelo U, Beyna T, Busch O, Deprez PH, Kunovsky L, Larghi A, Manes G, Moss A, Napoleon B, Nayar M, Pérez-Cuadrado-Robles E, Seewald S, Barthet M, van Hooft JE
Endoscopy 2021 Apr;53(4):429-448. Epub 2021 Mar 16 doi: 10.1055/a-1397-3198. PMID: 33728632
Pourmand K, Itzkowitz SH
Curr Gastroenterol Rep 2016 May;18(5):23. doi: 10.1007/s11894-016-0497-x. PMID: 27086004
Lin J, Goldblum JR, Bennett AE, Bronner MP, Liu X
Am J Surg Pathol 2012 Feb;36(2):292-5. doi: 10.1097/PAS.0b013e318236e4d2. PMID: 22082602
Schottenfeld D, Beebe-Dimmer JL, Vigneau FD
Ann Epidemiol 2009 Jan;19(1):58-69. doi: 10.1016/j.annepidem.2008.10.004. PMID: 19064190Free PMC Article

Diagnosis

Lucaciu L, Yano T, Saurin JC
Best Pract Res Clin Gastroenterol 2023 Jun-Aug;64-65:101852. Epub 2023 Jul 22 doi: 10.1016/j.bpg.2023.101852. PMID: 37652652
Campos ST, Bruno MJ
Gastrointest Endosc Clin N Am 2022 Jul;32(3):545-562. Epub 2022 May 11 doi: 10.1016/j.giec.2022.01.005. PMID: 35691696
Yamamoto K, Iwasaki E, Itoi T
Expert Rev Gastroenterol Hepatol 2020 Jun;14(6):435-444. Epub 2020 May 22 doi: 10.1080/17474124.2020.1766965. PMID: 32380873
Saurin JC, Benech N, Pioche M
Curr Opin Gastroenterol 2019 May;35(3):250-256. doi: 10.1097/MOG.0000000000000518. PMID: 30844897
Mönkemüller K, Bellutti M, Fry LC, Malfertheiner P
Best Pract Res Clin Gastroenterol 2008;22(5):789-811. doi: 10.1016/j.bpg.2008.05.005. PMID: 18790433

Therapy

Kiran RP, Kochhar GS, Kariv R, Rex DK, Sugita A, Rubin DT, Navaneethan U, Hull TL, Ko HM, Liu X, Kachnic LA, Strong S, Iacucci M, Bemelman W, Fleshner P, Safyan RA, Kotze PG, D'Hoore A, Faiz O, Lo S, Ashburn JH, Spinelli A, Bernstein CN, Kane SV, Cross RK, Schairer J, McCormick JT, Farraye FA, Chang S, Scherl EJ, Schwartz DA, Bruining DH, Philpott J, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sandborn WJ, Silverberg MS, Pardi DS, Church JM, Shen B
Lancet Gastroenterol Hepatol 2022 Sep;7(9):871-893. Epub 2022 Jul 5 doi: 10.1016/S2468-1253(22)00039-5. PMID: 35798022
Yamamoto K, Iwasaki E, Itoi T
Expert Rev Gastroenterol Hepatol 2020 Jun;14(6):435-444. Epub 2020 May 22 doi: 10.1080/17474124.2020.1766965. PMID: 32380873
Thakkar K, Fishman DS, Gilger MA
Curr Opin Pediatr 2012 Oct;24(5):632-7. doi: 10.1097/MOP.0b013e328357419f. PMID: 22890064
Nayeb-Hashemi H, Kaunitz JD
Curr Opin Gastroenterol 2009 Nov;25(6):537-43. doi: 10.1097/MOG.0b013e328330da7b. PMID: 19654540
Mönkemüller K, Bellutti M, Fry LC, Malfertheiner P
Best Pract Res Clin Gastroenterol 2008;22(5):789-811. doi: 10.1016/j.bpg.2008.05.005. PMID: 18790433

Prognosis

Pourmand K, Itzkowitz SH
Curr Gastroenterol Rep 2016 May;18(5):23. doi: 10.1007/s11894-016-0497-x. PMID: 27086004
Lin J, Goldblum JR, Bennett AE, Bronner MP, Liu X
Am J Surg Pathol 2012 Feb;36(2):292-5. doi: 10.1097/PAS.0b013e318236e4d2. PMID: 22082602
Froissart R, Piraud M, Boudjemline AM, Vianey-Saban C, Petit F, Hubert-Buron A, Eberschweiler PT, Gajdos V, Labrune P
Orphanet J Rare Dis 2011 May 20;6:27. doi: 10.1186/1750-1172-6-27. PMID: 21599942Free PMC Article
Schottenfeld D, Beebe-Dimmer JL, Vigneau FD
Ann Epidemiol 2009 Jan;19(1):58-69. doi: 10.1016/j.annepidem.2008.10.004. PMID: 19064190Free PMC Article
Mönkemüller K, Bellutti M, Fry LC, Malfertheiner P
Best Pract Res Clin Gastroenterol 2008;22(5):789-811. doi: 10.1016/j.bpg.2008.05.005. PMID: 18790433

Clinical prediction guides

Vanoli A, Grillo F, Furlan D, Arpa G, Grami O, Guerini C, Riboni R, Mastracci L, Di Sabatino A
Int J Mol Sci 2021 Apr 22;22(9) doi: 10.3390/ijms22094388. PMID: 33922305Free PMC Article
Xue Y, Reid MD
Surg Pathol Clin 2020 Sep;13(3):453-467. Epub 2020 Jul 15 doi: 10.1016/j.path.2020.05.005. PMID: 32773194
Altindag SD, Cakir E, Ekinci N, Avci A, Dilek FH
Ann Diagn Pathol 2019 Jun;40:66-71. Epub 2019 Apr 3 doi: 10.1016/j.anndiagpath.2019.04.003. PMID: 31031217
Espinel J, Pinedo E, Ojeda V, Guerra Del Río M
Rev Esp Enferm Dig 2016 May;108(5):271-8. doi: 10.17235/reed.2016.3867/2015. PMID: 27187501
Mönkemüller K, Bellutti M, Fry LC, Malfertheiner P
Best Pract Res Clin Gastroenterol 2008;22(5):789-811. doi: 10.1016/j.bpg.2008.05.005. PMID: 18790433

Recent systematic reviews

Garg R, Thind K, Bhalla J, Simonson MT, Simons-Linares CR, Singh A, Joyce D, Chahal P
Surg Endosc 2023 Jul;37(7):5022-5044. Epub 2023 May 23 doi: 10.1007/s00464-023-10083-0. PMID: 37221416
Morano WF, Gleeson EM, Sullivan SH, Padmanaban V, Mapow BL, Shewokis PA, Esquivel J, Bowne WB
Am Surg 2018 Feb 1;84(2):273-281. PMID: 29580358
Mendonça EQ, Bernardo WM, Moura EG, Chaves DM, Kondo A, Pu LZ, Baracat FI
Clinics (Sao Paulo) 2016 Jan;71(1):28-35. doi: 10.6061/clinics/2016(01)06. PMID: 26872081Free PMC Article
Askew J, Connor S
HPB (Oxford) 2013 Nov;15(11):829-38. Epub 2013 Jan 10 doi: 10.1111/hpb.12038. PMID: 23458317Free PMC Article
Cooper K, Squires H, Carroll C, Papaioannou D, Booth A, Logan RF, Maguire C, Hind D, Tappenden P
Health Technol Assess 2010 Jun;14(32):1-206. doi: 10.3310/hta14320. PMID: 20594533

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