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Central nervous system rhabdomyosarcoma

MedGen UID:
232043
•Concept ID:
C1332891
•
Neoplastic Process
Synonyms: Central Nervous System Rhabdomyosarcoma; central nervous system rhabdomyosarcoma; central nervous system rhabdomyosarcoma (disease); CNS Rhabdomyosarcoma; CNS rhabdomyosarcoma; rhabdomyosarcoma (disease) of central nervous system; Rhabdomyosarcoma of Central Nervous System; rhabdomyosarcoma of central nervous system; Rhabdomyosarcoma of CNS; rhabdomyosarcoma of CNS; Rhabdomyosarcoma of the Central Nervous System; rhabdomyosarcoma of the central nervous system; Rhabdomyosarcoma of the CNS; rhabdomyosarcoma of the CNS
 
Monarch Initiative: MONDO:0002850

Definition

A malignant mesenchymal neoplasm with skeletal muscle differentiation affecting the central nervous system. [from NCI]

Professional guidelines

PubMed

Differential Diagnosis in Hypophysitis: First Report on a Spindle Cell Rhabdomyosarcoma of the Pituitary Gland.
Ahmeti H, Jüttner E, Röcken C, Jansen O, Laudes M, Synowitz M
J Neurol Surg A Cent Eur Neurosurg 2023 May;84(3):295-299. Epub 2021 Nov 15 doi: 10.1055/s-0041-1735857. PMID: 34781400
Vertebroplasty as a palliative treatment option for intractable pain in pediatric patients with spinal tumors.
Cardarelli-Leite L, Rassekh SR, D'Ortenzio R, Heran MKS
Pediatr Blood Cancer 2021 Dec;68(12):e29307. Epub 2021 Aug 27 doi: 10.1002/pbc.29307. PMID: 34453400
Evaluation of gefitinib for treatment of refractory solid tumors and central nervous system malignancies in pediatric patients.
Freeman BB 3rd, Daw NC, Geyer JR, Furman WL, Stewart CF
Cancer Invest 2006 Apr-May;24(3):310-7. doi: 10.1080/07357900600632058. PMID: 16809160

Recent clinical studies

Etiology

DNA repair alterations in common pediatric malignancies.
Papaefthymiou MA, Giaginis CT, Theocharis SE
Med Sci Monit 2008 Jan;14(1):RA8-15. PMID: 18160950

Diagnosis

Primary intraventricular central nervous system rhabdomyosarcoma.
Rao KI, Malicki DM, Crawford JR
Pediatr Neurol 2015 Jan;52(1):130-1. Epub 2014 Aug 25 doi: 10.1016/j.pediatrneurol.2014.08.007. PMID: 25444091

Prognosis

Primary intraventricular central nervous system rhabdomyosarcoma.
Rao KI, Malicki DM, Crawford JR
Pediatr Neurol 2015 Jan;52(1):130-1. Epub 2014 Aug 25 doi: 10.1016/j.pediatrneurol.2014.08.007. PMID: 25444091

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