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Pediatric lymphoma

MedGen UID:
232062
•Concept ID:
C1332979
•
Neoplastic Process
Synonyms: Childhood Lymphoma; childhood lymphoma; Pediatric Lymphoma; pediatric lymphoma
 
Monarch Initiative: MONDO:0003659

Definition

A Hodgkin or non-Hodgkin lymphoma that occurs during childhood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPediatric lymphoma

Professional guidelines

PubMed

Modern Classification and Management of Pediatric B-cell Leukemia and Lymphoma.
Kovach AE, Raca G
Surg Pathol Clin 2023 Jun;16(2):249-266. Epub 2023 Mar 8 doi: 10.1016/j.path.2023.01.001. PMID: 37149359
Pharmacotherapeutic Management of Pediatric Lymphoma.
Mauz-Körholz C, Ströter N, Baumann J, Botzen A, Körholz K, Körholz D
Paediatr Drugs 2018 Feb;20(1):43-57. doi: 10.1007/s40272-017-0265-x. PMID: 29127674
International Working Group consensus response evaluation criteria in lymphoma (RECIL 2017).
Younes A, Hilden P, Coiffier B, Hagenbeek A, Salles G, Wilson W, Seymour JF, Kelly K, Gribben J, Pfreunschuh M, Morschhauser F, Schoder H, Zelenetz AD, Rademaker J, Advani R, Valente N, Fortpied C, Witzig TE, Sehn LH, Engert A, Fisher RI, Zinzani PL, Federico M, Hutchings M, Bollard C, Trneny M, Elsayed YA, Tobinai K, Abramson JS, Fowler N, Goy A, Smith M, Ansell S, Kuruvilla J, Dreyling M, Thieblemont C, Little RF, Aurer I, Van Oers MHJ, Takeshita K, Gopal A, Rule S, de Vos S, Kloos I, Kaminski MS, Meignan M, Schwartz LH, Leonard JP, Schuster SJ, Seshan VE
Ann Oncol 2017 Jul 1;28(7):1436-1447. doi: 10.1093/annonc/mdx097. PMID: 28379322Free PMC Article

Recent clinical studies

Etiology

Cardiotoxicity in pediatric lymphoma survivors.
Bansal N, Joshi C, Adams MJ, Hutchins K, Ray A, Lipshultz SE
Expert Rev Cardiovasc Ther 2021 Nov;19(11):957-974. Epub 2021 Dec 27 doi: 10.1080/14779072.2021.2013811. PMID: 34958622
Surveillance imaging in pediatric lymphoma.
Voss SD, Cairo MS
Pediatr Radiol 2019 Oct;49(11):1565-1573. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04511-4. PMID: 31620855
Imaging for diagnosis, staging and response assessment of Hodgkin lymphoma and non-Hodgkin lymphoma.
McCarten KM, Nadel HR, Shulkin BL, Cho SY
Pediatr Radiol 2019 Oct;49(11):1545-1564. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04529-8. PMID: 31620854
Pediatric Lymphoma.
Buhtoiarov IN
Pediatr Rev 2017 Sep;38(9):410-423. doi: 10.1542/pir.2016-0152. PMID: 28864732
International Working Group consensus response evaluation criteria in lymphoma (RECIL 2017).
Younes A, Hilden P, Coiffier B, Hagenbeek A, Salles G, Wilson W, Seymour JF, Kelly K, Gribben J, Pfreunschuh M, Morschhauser F, Schoder H, Zelenetz AD, Rademaker J, Advani R, Valente N, Fortpied C, Witzig TE, Sehn LH, Engert A, Fisher RI, Zinzani PL, Federico M, Hutchings M, Bollard C, Trneny M, Elsayed YA, Tobinai K, Abramson JS, Fowler N, Goy A, Smith M, Ansell S, Kuruvilla J, Dreyling M, Thieblemont C, Little RF, Aurer I, Van Oers MHJ, Takeshita K, Gopal A, Rule S, de Vos S, Kloos I, Kaminski MS, Meignan M, Schwartz LH, Leonard JP, Schuster SJ, Seshan VE
Ann Oncol 2017 Jul 1;28(7):1436-1447. doi: 10.1093/annonc/mdx097. PMID: 28379322Free PMC Article

Diagnosis

Surveillance imaging in pediatric lymphoma.
Voss SD, Cairo MS
Pediatr Radiol 2019 Oct;49(11):1565-1573. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04511-4. PMID: 31620855
Imaging for diagnosis, staging and response assessment of Hodgkin lymphoma and non-Hodgkin lymphoma.
McCarten KM, Nadel HR, Shulkin BL, Cho SY
Pediatr Radiol 2019 Oct;49(11):1545-1564. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04529-8. PMID: 31620854
Pediatric Lymphoma.
Buhtoiarov IN
Pediatr Rev 2017 Sep;38(9):410-423. doi: 10.1542/pir.2016-0152. PMID: 28864732
International Working Group consensus response evaluation criteria in lymphoma (RECIL 2017).
Younes A, Hilden P, Coiffier B, Hagenbeek A, Salles G, Wilson W, Seymour JF, Kelly K, Gribben J, Pfreunschuh M, Morschhauser F, Schoder H, Zelenetz AD, Rademaker J, Advani R, Valente N, Fortpied C, Witzig TE, Sehn LH, Engert A, Fisher RI, Zinzani PL, Federico M, Hutchings M, Bollard C, Trneny M, Elsayed YA, Tobinai K, Abramson JS, Fowler N, Goy A, Smith M, Ansell S, Kuruvilla J, Dreyling M, Thieblemont C, Little RF, Aurer I, Van Oers MHJ, Takeshita K, Gopal A, Rule S, de Vos S, Kloos I, Kaminski MS, Meignan M, Schwartz LH, Leonard JP, Schuster SJ, Seshan VE
Ann Oncol 2017 Jul 1;28(7):1436-1447. doi: 10.1093/annonc/mdx097. PMID: 28379322Free PMC Article
Pediatric lymphoma diagnosis: role of FNAC, biopsy, immunohistochemistry and molecular diagnostics.
Iyer VK
Indian J Pediatr 2013 Sep;80(9):756-63. Epub 2013 Aug 8 doi: 10.1007/s12098-013-1128-2. PMID: 23925793

Therapy

Sequential different B-cell antigen-targeted CAR T-cell therapy for pediatric refractory/relapsed Burkitt lymphoma.
Liu Y, Deng B, Hu B, Zhang W, Zhu Q, Liu Y, Wang S, Zhang P, Yang Y, Yang J, Zheng Q, Yu X, Gao Z, Zhou C, Han W, Yang J, Jin L, Tong C, Chang AH, Zhang Y
Blood Adv 2022 Feb 8;6(3):717-730. doi: 10.1182/bloodadvances.2021004557. PMID: 34521107Free PMC Article
Cardiotoxicity in pediatric lymphoma survivors.
Bansal N, Joshi C, Adams MJ, Hutchins K, Ray A, Lipshultz SE
Expert Rev Cardiovasc Ther 2021 Nov;19(11):957-974. Epub 2021 Dec 27 doi: 10.1080/14779072.2021.2013811. PMID: 34958622
Imaging for diagnosis, staging and response assessment of Hodgkin lymphoma and non-Hodgkin lymphoma.
McCarten KM, Nadel HR, Shulkin BL, Cho SY
Pediatr Radiol 2019 Oct;49(11):1545-1564. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04529-8. PMID: 31620854
Pharmacotherapeutic Management of Pediatric Lymphoma.
Mauz-Körholz C, Ströter N, Baumann J, Botzen A, Körholz K, Körholz D
Paediatr Drugs 2018 Feb;20(1):43-57. doi: 10.1007/s40272-017-0265-x. PMID: 29127674
International Working Group consensus response evaluation criteria in lymphoma (RECIL 2017).
Younes A, Hilden P, Coiffier B, Hagenbeek A, Salles G, Wilson W, Seymour JF, Kelly K, Gribben J, Pfreunschuh M, Morschhauser F, Schoder H, Zelenetz AD, Rademaker J, Advani R, Valente N, Fortpied C, Witzig TE, Sehn LH, Engert A, Fisher RI, Zinzani PL, Federico M, Hutchings M, Bollard C, Trneny M, Elsayed YA, Tobinai K, Abramson JS, Fowler N, Goy A, Smith M, Ansell S, Kuruvilla J, Dreyling M, Thieblemont C, Little RF, Aurer I, Van Oers MHJ, Takeshita K, Gopal A, Rule S, de Vos S, Kloos I, Kaminski MS, Meignan M, Schwartz LH, Leonard JP, Schuster SJ, Seshan VE
Ann Oncol 2017 Jul 1;28(7):1436-1447. doi: 10.1093/annonc/mdx097. PMID: 28379322Free PMC Article

Prognosis

Pediatric Lymphoma and Solid Tumors Associated With Cancer Susceptibility Syndromes.
Kara B, Koksal Y
J Pediatr Hematol Oncol 2020 Oct;42(7):438-445. doi: 10.1097/MPH.0000000000001798. PMID: 32282651
Imaging for diagnosis, staging and response assessment of Hodgkin lymphoma and non-Hodgkin lymphoma.
McCarten KM, Nadel HR, Shulkin BL, Cho SY
Pediatr Radiol 2019 Oct;49(11):1545-1564. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04529-8. PMID: 31620854
Pediatric Lymphoma.
Buhtoiarov IN
Pediatr Rev 2017 Sep;38(9):410-423. doi: 10.1542/pir.2016-0152. PMID: 28864732
International Working Group consensus response evaluation criteria in lymphoma (RECIL 2017).
Younes A, Hilden P, Coiffier B, Hagenbeek A, Salles G, Wilson W, Seymour JF, Kelly K, Gribben J, Pfreunschuh M, Morschhauser F, Schoder H, Zelenetz AD, Rademaker J, Advani R, Valente N, Fortpied C, Witzig TE, Sehn LH, Engert A, Fisher RI, Zinzani PL, Federico M, Hutchings M, Bollard C, Trneny M, Elsayed YA, Tobinai K, Abramson JS, Fowler N, Goy A, Smith M, Ansell S, Kuruvilla J, Dreyling M, Thieblemont C, Little RF, Aurer I, Van Oers MHJ, Takeshita K, Gopal A, Rule S, de Vos S, Kloos I, Kaminski MS, Meignan M, Schwartz LH, Leonard JP, Schuster SJ, Seshan VE
Ann Oncol 2017 Jul 1;28(7):1436-1447. doi: 10.1093/annonc/mdx097. PMID: 28379322Free PMC Article
Stem cell transplantation for pediatric lymphoma: past, present and future.
Bradley MB, Cairo MS
Bone Marrow Transplant 2008 Jan;41(2):149-58. Epub 2007 Dec 17 doi: 10.1038/sj.bmt.1705948. PMID: 18084337

Clinical prediction guides

Pediatric lymphoma patients in Malawi present with poor health-related quality of life at diagnosis and improve throughout treatment and follow-up across all Pediatric PROMIS-25 domains.
Ellis GK, Chapman H, Manda A, Salima A, Itimu S, Banda G, Seguin R, Manda G, Butia M, Huibers M, Ozuah N, Tilly A, Stover AM, Basch E, Gopal S, Reeve BB, Westmoreland KD
Pediatr Blood Cancer 2021 Oct;68(10):e29257. Epub 2021 Aug 2 doi: 10.1002/pbc.29257. PMID: 34339099Free PMC Article
Value of baseline and end of chemotherapy (18)F-FDG PET/CT in pediatric patients with Burkitt lymphoma.
Xiao Z, Mo Y, Long W, Li R, Li X, Wei Y, Fan W, Zhang X
Leuk Lymphoma 2021 Dec;62(12):2873-2881. Epub 2021 Jun 24 doi: 10.1080/10428194.2021.1941933. PMID: 34165390
Imaging for diagnosis, staging and response assessment of Hodgkin lymphoma and non-Hodgkin lymphoma.
McCarten KM, Nadel HR, Shulkin BL, Cho SY
Pediatr Radiol 2019 Oct;49(11):1545-1564. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04529-8. PMID: 31620854
International Working Group consensus response evaluation criteria in lymphoma (RECIL 2017).
Younes A, Hilden P, Coiffier B, Hagenbeek A, Salles G, Wilson W, Seymour JF, Kelly K, Gribben J, Pfreunschuh M, Morschhauser F, Schoder H, Zelenetz AD, Rademaker J, Advani R, Valente N, Fortpied C, Witzig TE, Sehn LH, Engert A, Fisher RI, Zinzani PL, Federico M, Hutchings M, Bollard C, Trneny M, Elsayed YA, Tobinai K, Abramson JS, Fowler N, Goy A, Smith M, Ansell S, Kuruvilla J, Dreyling M, Thieblemont C, Little RF, Aurer I, Van Oers MHJ, Takeshita K, Gopal A, Rule S, de Vos S, Kloos I, Kaminski MS, Meignan M, Schwartz LH, Leonard JP, Schuster SJ, Seshan VE
Ann Oncol 2017 Jul 1;28(7):1436-1447. doi: 10.1093/annonc/mdx097. PMID: 28379322Free PMC Article
A rare pediatric case of a thymic cytotoxic and lymphoblastic T/NK cell lymphoma.
Gaiser T, Haedicke W, Becker MR
Int J Clin Exp Pathol 2010 Mar 20;3(4):437-42. PMID: 20490334Free PMC Article

Recent systematic reviews

Clinicopathological analysis of oral Burkitt's lymphoma in pediatric patients: A systematic review.
Rodrigues-Fernandes CI, Pérez-de-Oliveira ME, Aristizabal Arboleda LP, Fonseca FP, Lopes MA, Vargas PA, Santos-Silva AR
Int J Pediatr Otorhinolaryngol 2020 Jul;134:110033. Epub 2020 Apr 5 doi: 10.1016/j.ijporl.2020.110033. PMID: 32302884

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