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Colorectal Inflammatory Polyp

MedGen UID:
232093
Concept ID:
C1333111
Disease or Syndrome
Synonyms: Inflammatory Polyp of Large Bowel; Inflammatory Polyp of the Large Bowel; Large Bowel Inflammatory Polyp; Large Intestinal Inflammatory Polyp

Definition

A non-neoplastic polypoid lesion in the colon and rectum. It may arise in a background of inflammatory bowel disease or colitis. It is characterized by the presence of a distorted epithelium, inflammation, and fibrosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColorectal Inflammatory Polyp

Professional guidelines

PubMed

Issaka RB, Chan AT, Gupta S
Gastroenterology 2023 Nov;165(5):1280-1291. Epub 2023 Sep 21 doi: 10.1053/j.gastro.2023.06.033. PMID: 37737817Free PMC Article
Shen B, Kochhar GS, Rubin DT, Kane SV, Navaneethan U, Bernstein CN, Cross RK, Sugita A, Schairer J, Kiran RP, Fleshner P, McCormick JT, D'Hoore A, Shah SA, Farraye FA, Kariv R, Liu X, Rosh J, Chang S, Scherl E, Schwartz DA, Kotze PG, Bruining DH, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, Picoraro JA, Vermeire S, Sandborn WJ, Silverberg MS, Pardi DS
Lancet Gastroenterol Hepatol 2022 Jan;7(1):69-95. Epub 2021 Nov 10 doi: 10.1016/S2468-1253(21)00214-4. PMID: 34774224
US Preventive Services Task Force, Davidson KW, Barry MJ, Mangione CM, Cabana M, Caughey AB, Davis EM, Donahue KE, Doubeni CA, Krist AH, Kubik M, Li L, Ogedegbe G, Owens DK, Pbert L, Silverstein M, Stevermer J, Tseng CW, Wong JB
JAMA 2021 May 18;325(19):1965-1977. doi: 10.1001/jama.2021.6238. PMID: 34003218

Recent clinical studies

Etiology

Shen B, Kochhar GS, Rubin DT, Kane SV, Navaneethan U, Bernstein CN, Cross RK, Sugita A, Schairer J, Kiran RP, Fleshner P, McCormick JT, D'Hoore A, Shah SA, Farraye FA, Kariv R, Liu X, Rosh J, Chang S, Scherl E, Schwartz DA, Kotze PG, Bruining DH, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, Picoraro JA, Vermeire S, Sandborn WJ, Silverberg MS, Pardi DS
Lancet Gastroenterol Hepatol 2022 Jan;7(1):69-95. Epub 2021 Nov 10 doi: 10.1016/S2468-1253(21)00214-4. PMID: 34774224
Bailie L, Loughrey MB, Coleman HG
Gastroenterology 2017 Jan;152(1):92-104. Epub 2016 Sep 14 doi: 10.1053/j.gastro.2016.09.003. PMID: 27639804
Bartel MJ, Picco MF, Wallace MB
Gastrointest Endosc Clin N Am 2015 Apr;25(2):243-60. doi: 10.1016/j.giec.2014.11.010. PMID: 25839685
Brosens LA, Langeveld D, van Hattem WA, Giardiello FM, Offerhaus GJ
World J Gastroenterol 2011 Nov 28;17(44):4839-44. doi: 10.3748/wjg.v17.i44.4839. PMID: 22171123Free PMC Article
Watne AL
J Surg Oncol 1997 Nov;66(3):207-14. doi: 10.1002/(sici)1096-9098(199711)66:3<207::aid-jso10>3.0.co;2-z. PMID: 9369968

Diagnosis

Areia M, Mori Y, Correale L, Repici A, Bretthauer M, Sharma P, Taveira F, Spadaccini M, Antonelli G, Ebigbo A, Kudo SE, Arribas J, Barua I, Kaminski MF, Messmann H, Rex DK, Dinis-Ribeiro M, Hassan C
Lancet Digit Health 2022 Jun;4(6):e436-e444. Epub 2022 Apr 13 doi: 10.1016/S2589-7500(22)00042-5. PMID: 35430151
US Preventive Services Task Force, Davidson KW, Barry MJ, Mangione CM, Cabana M, Caughey AB, Davis EM, Donahue KE, Doubeni CA, Krist AH, Kubik M, Li L, Ogedegbe G, Owens DK, Pbert L, Silverstein M, Stevermer J, Tseng CW, Wong JB
JAMA 2021 May 18;325(19):1965-1977. doi: 10.1001/jama.2021.6238. PMID: 34003218
Wijnands AM, de Jong ME, Lutgens MWMD, Hoentjen F, Elias SG, Oldenburg B; Dutch Initiative on Crohn and Colitis (ICC)
Gastroenterology 2021 Apr;160(5):1584-1598. Epub 2020 Dec 29 doi: 10.1053/j.gastro.2020.12.036. PMID: 33385426
Bartel MJ, Picco MF, Wallace MB
Gastrointest Endosc Clin N Am 2015 Apr;25(2):243-60. doi: 10.1016/j.giec.2014.11.010. PMID: 25839685
Brosens LA, Langeveld D, van Hattem WA, Giardiello FM, Offerhaus GJ
World J Gastroenterol 2011 Nov 28;17(44):4839-44. doi: 10.3748/wjg.v17.i44.4839. PMID: 22171123Free PMC Article

Therapy

Shen B, Kochhar GS, Rubin DT, Kane SV, Navaneethan U, Bernstein CN, Cross RK, Sugita A, Schairer J, Kiran RP, Fleshner P, McCormick JT, D'Hoore A, Shah SA, Farraye FA, Kariv R, Liu X, Rosh J, Chang S, Scherl E, Schwartz DA, Kotze PG, Bruining DH, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, Picoraro JA, Vermeire S, Sandborn WJ, Silverberg MS, Pardi DS
Lancet Gastroenterol Hepatol 2022 Jan;7(1):69-95. Epub 2021 Nov 10 doi: 10.1016/S2468-1253(21)00214-4. PMID: 34774224
US Preventive Services Task Force, Davidson KW, Barry MJ, Mangione CM, Cabana M, Caughey AB, Davis EM, Donahue KE, Doubeni CA, Krist AH, Kubik M, Li L, Ogedegbe G, Owens DK, Pbert L, Silverstein M, Stevermer J, Tseng CW, Wong JB
JAMA 2021 May 18;325(19):1965-1977. doi: 10.1001/jama.2021.6238. PMID: 34003218
Wijnands AM, de Jong ME, Lutgens MWMD, Hoentjen F, Elias SG, Oldenburg B; Dutch Initiative on Crohn and Colitis (ICC)
Gastroenterology 2021 Apr;160(5):1584-1598. Epub 2020 Dec 29 doi: 10.1053/j.gastro.2020.12.036. PMID: 33385426
Bailie L, Loughrey MB, Coleman HG
Gastroenterology 2017 Jan;152(1):92-104. Epub 2016 Sep 14 doi: 10.1053/j.gastro.2016.09.003. PMID: 27639804
Wakeman C, Keenan J, Eteuati J, Hollington P, Eglinton T, Frizelle F
ANZ J Surg 2017 Dec;87(12):E228-E232. Epub 2015 Dec 21 doi: 10.1111/ans.13392. PMID: 26686322

Prognosis

Sharma A, Kumar R, Yadav G, Garg P
Cancer Lett 2023 Jul 1;565:216238. Epub 2023 May 19 doi: 10.1016/j.canlet.2023.216238. PMID: 37211068
Wijnands AM, de Jong ME, Lutgens MWMD, Hoentjen F, Elias SG, Oldenburg B; Dutch Initiative on Crohn and Colitis (ICC)
Gastroenterology 2021 Apr;160(5):1584-1598. Epub 2020 Dec 29 doi: 10.1053/j.gastro.2020.12.036. PMID: 33385426
Wakeman C, Keenan J, Eteuati J, Hollington P, Eglinton T, Frizelle F
ANZ J Surg 2017 Dec;87(12):E228-E232. Epub 2015 Dec 21 doi: 10.1111/ans.13392. PMID: 26686322
Lanza G, Messerini L, Gafà R, Risio M; Gruppo Italiano Patologi Apparato Digerente (GIPAD); Società Italiana di Anatomia Patologica e Citopatologia Diagnostica/International Academy of Pathology, Italian division (SIAPEC/IAP)
Dig Liver Dis 2011 Mar;43 Suppl 4:S344-55. doi: 10.1016/S1590-8658(11)60590-2. PMID: 21459340
Wallace HM, Caslake R
Eur J Gastroenterol Hepatol 2001 Sep;13(9):1033-9. doi: 10.1097/00042737-200109000-00006. PMID: 11564951

Clinical prediction guides

Sung LB, Coleman HG, Shivappa N, Hébert JR, Murff HJ, Milne GL, Ness RM, Smalley WE, Zheng W, Shrubsole MJ
Nutr Cancer 2023;75(10):1900-1910. Epub 2023 Nov 30 doi: 10.1080/01635581.2023.2261651. PMID: 37791878Free PMC Article
Sharma A, Kumar R, Yadav G, Garg P
Cancer Lett 2023 Jul 1;565:216238. Epub 2023 May 19 doi: 10.1016/j.canlet.2023.216238. PMID: 37211068
Wijnands AM, de Jong ME, Lutgens MWMD, Hoentjen F, Elias SG, Oldenburg B; Dutch Initiative on Crohn and Colitis (ICC)
Gastroenterology 2021 Apr;160(5):1584-1598. Epub 2020 Dec 29 doi: 10.1053/j.gastro.2020.12.036. PMID: 33385426
Bailie L, Loughrey MB, Coleman HG
Gastroenterology 2017 Jan;152(1):92-104. Epub 2016 Sep 14 doi: 10.1053/j.gastro.2016.09.003. PMID: 27639804
Lanza G, Messerini L, Gafà R, Risio M; Gruppo Italiano Patologi Apparato Digerente (GIPAD); Società Italiana di Anatomia Patologica e Citopatologia Diagnostica/International Academy of Pathology, Italian division (SIAPEC/IAP)
Dig Liver Dis 2011 Mar;43 Suppl 4:S344-55. doi: 10.1016/S1590-8658(11)60590-2. PMID: 21459340

Recent systematic reviews

Wijnands AM, de Jong ME, Lutgens MWMD, Hoentjen F, Elias SG, Oldenburg B; Dutch Initiative on Crohn and Colitis (ICC)
Gastroenterology 2021 Apr;160(5):1584-1598. Epub 2020 Dec 29 doi: 10.1053/j.gastro.2020.12.036. PMID: 33385426
Hussan H, Clinton SK, Roberts K, Bailey MT
World J Gastroenterol 2017 Dec 28;23(48):8626-8650. doi: 10.3748/wjg.v23.i48.8626. PMID: 29358871Free PMC Article
Vleugels JLA, Hazewinkel Y, Fockens P, Dekker E
Gastrointest Endosc 2017 Jun;85(6):1169-1176.e1. Epub 2016 Dec 23 doi: 10.1016/j.gie.2016.12.014. PMID: 28024986
Bailie L, Loughrey MB, Coleman HG
Gastroenterology 2017 Jan;152(1):92-104. Epub 2016 Sep 14 doi: 10.1053/j.gastro.2016.09.003. PMID: 27639804
Szylberg Ł, Janiczek M, Popiel A, Marszałek A
Adv Clin Exp Med 2015 Jul-Aug;24(4):555-63. doi: 10.17219/acem/31239. PMID: 26469098

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