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Desmoplastic melanoma

MedGen UID:
232127
Concept ID:
C1333280
Neoplastic Process
Synonyms: desmoplastic cutaneous (skin) melanoma; Desmoplastic Melanoma; desmoplastic melanoma
 
Monarch Initiative: MONDO:0044785

Definition

A melanoma of the skin characterized by a proliferation of atypical spindled melanocytes in the dermis, in a background of abundant collagen. It usually presents as an amelanotic raised nodular lesion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDesmoplastic melanoma

Professional guidelines

PubMed

Fernandez-Flores A, Singh R, Cassarino DS
Head Neck Pathol 2023 Mar;17(1):143-153. Epub 2023 Mar 16 doi: 10.1007/s12105-023-01536-y. PMID: 36928737Free PMC Article
Dunne JA, Adigbli G
J Surg Oncol 2022 Feb;125(2):227-228. Epub 2021 Sep 17 doi: 10.1002/jso.26677. PMID: 34535908
Wuthrick EJ, Chablani P
Semin Radiat Oncol 2019 Apr;29(2):166-170. doi: 10.1016/j.semradonc.2018.11.006. PMID: 30827455

Recent clinical studies

Etiology

Hughes TM, Williams GJ, Gyorki DE, Kelly JW, Stretch JR, Varey AHR, Hong AM, Scolyer RA, Thompson JF
J Eur Acad Dermatol Venereol 2021 Jun;35(6):1290-1298. Epub 2021 Mar 3 doi: 10.1111/jdv.17154. PMID: 33544941
Kiuru M, Busam KJ
Lab Invest 2017 Feb;97(2):146-157. Epub 2017 Jan 9 doi: 10.1038/labinvest.2016.142. PMID: 28067895Free PMC Article
Pavri SN, Clune J, Ariyan S, Narayan D
Plast Reconstr Surg 2016 Aug;138(2):330e-340e. doi: 10.1097/PRS.0000000000002367. PMID: 27465194
Frydenlund N, Mahalingam M
Adv Anat Pathol 2015 Jul;22(4):227-41. doi: 10.1097/PAP.0000000000000076. PMID: 26050260
Chen LL, Jaimes N, Barker CA, Busam KJ, Marghoob AA
J Am Acad Dermatol 2013 May;68(5):825-33. Epub 2012 Dec 23 doi: 10.1016/j.jaad.2012.10.041. PMID: 23267722Free PMC Article

Diagnosis

Lallas A, Paschou E, Manoli SM, Papageorgiou C, Spyridis I, Liopyris K, Bobos M, Moutsoudis A, Lazaridou E, Apalla Z
Ital J Dermatol Venerol 2021 Jun;156(3):274-288. Epub 2020 Dec 14 doi: 10.23736/S2784-8671.20.06784-X. PMID: 33314891
Gong HZ, Zheng HY, Li J
Melanoma Res 2019 Jun;29(3):221-230. doi: 10.1097/CMR.0000000000000571. PMID: 30672881
Cabrera R, Recule F
Am J Clin Dermatol 2018 Nov;19(Suppl 1):15-23. doi: 10.1007/s40257-018-0373-6. PMID: 30374898Free PMC Article
Pavri SN, Clune J, Ariyan S, Narayan D
Plast Reconstr Surg 2016 Aug;138(2):330e-340e. doi: 10.1097/PRS.0000000000002367. PMID: 27465194
Ohsie SJ, Sarantopoulos GP, Cochran AJ, Binder SW
J Cutan Pathol 2008 May;35(5):433-44. doi: 10.1111/j.1600-0560.2007.00891.x. PMID: 18399807

Therapy

Hadfield MJ, Helsing R, Grant-Kels JM
Melanoma Res 2020 Oct;30(5):429-432. doi: 10.1097/CMR.0000000000000679. PMID: 32590412
Yang K, Mahalingam M
J Am Acad Dermatol 2020 Aug;83(2):523-531. Epub 2020 Feb 14 doi: 10.1016/j.jaad.2020.02.014. PMID: 32068045
DeWane ME, Kelsey A, Oliviero M, Rabinovitz H, Grant-Kels JM
J Am Acad Dermatol 2019 Sep;81(3):823-833. Epub 2019 Mar 28 doi: 10.1016/j.jaad.2019.03.066. PMID: 30930085
Wuthrick EJ, Chablani P
Semin Radiat Oncol 2019 Apr;29(2):166-170. doi: 10.1016/j.semradonc.2018.11.006. PMID: 30827455
Busam KJ
Adv Anat Pathol 2005 Mar;12(2):92-102. doi: 10.1097/01.pap.0000155071.86944.a6. PMID: 15731577

Prognosis

Gong HZ, Zheng HY, Li J
Melanoma Res 2019 Jun;29(3):221-230. doi: 10.1097/CMR.0000000000000571. PMID: 30672881
Nicolson NG, Han D
J Surg Oncol 2019 Jan;119(2):208-215. Epub 2018 Nov 27 doi: 10.1002/jso.25317. PMID: 30481377
Cabrera R, Recule F
Am J Clin Dermatol 2018 Nov;19(Suppl 1):15-23. doi: 10.1007/s40257-018-0373-6. PMID: 30374898Free PMC Article
Busam KJ
Clin Lab Med 2011 Jun;31(2):321-30. doi: 10.1016/j.cll.2011.03.009. PMID: 21549245
Ohsie SJ, Sarantopoulos GP, Cochran AJ, Binder SW
J Cutan Pathol 2008 May;35(5):433-44. doi: 10.1111/j.1600-0560.2007.00891.x. PMID: 18399807

Clinical prediction guides

Gerami P, Kim D, Zhang B, Compres EV, Khan AU, Yazdan P, Guitart J, Busam K
Am J Dermatopathol 2020 Dec;42(12):916-922. doi: 10.1097/DAD.0000000000001754. PMID: 32732692Free PMC Article
Khan F, Strohl A, Allen PD, Doerr TD
Otolaryngol Head Neck Surg 2017 Oct;157(4):648-656. Epub 2017 Aug 22 doi: 10.1177/0194599817725696. PMID: 28828926
Dunne JA, Wormald JC, Steele J, Woods E, Odili J, Powell BW
J Plast Reconstr Aesthet Surg 2017 Feb;70(2):274-280. Epub 2016 Nov 16 doi: 10.1016/j.bjps.2016.11.003. PMID: 28017261
Oliver DE, Patel KR, Parker D, Delman KA, Lawson DH, Kudchadkar RR, Khan MK
Melanoma Res 2015 Apr;25(2):95-102. doi: 10.1097/CMR.0000000000000139. PMID: 25588202
Chen LL, Jaimes N, Barker CA, Busam KJ, Marghoob AA
J Am Acad Dermatol 2013 May;68(5):825-33. Epub 2012 Dec 23 doi: 10.1016/j.jaad.2012.10.041. PMID: 23267722Free PMC Article

Recent systematic reviews

Ran NA, Veerabagu S, Miller CJ, Elenitsas R, Chu EY, Krausz AE
Dermatol Surg 2023 Apr 1;49(4):330-337. Epub 2023 Mar 1 doi: 10.1097/DSS.0000000000003699. PMID: 36857167
Hodson M, Feustel P, Davis L
J Plast Reconstr Aesthet Surg 2022 Dec;75(12):4441-4449. Epub 2022 Aug 28 doi: 10.1016/j.bjps.2022.08.044. PMID: 36283925
Dunne JA, Wormald JC, Steele J, Woods E, Odili J, Powell BW
J Plast Reconstr Aesthet Surg 2017 Feb;70(2):274-280. Epub 2016 Nov 16 doi: 10.1016/j.bjps.2016.11.003. PMID: 28017261
Kottschade LA, Grotz TE, Dronca RS, Salomao DR, Pulido JS, Wasif N, Jakub JW, Bagaria SP, Kumar R, Kaur JS, Morita SY, Moran SL, Nguyen JT, Nguyen EC, Hand JL, Erickson LA, Brewer JD, Baum CL, Miller RC, Swanson DL, Lowe V, Markovic SN
Am J Clin Oncol 2014 Dec;37(6):635-41. doi: 10.1097/COC.0b013e3182868e82. PMID: 23563206Free PMC Article
Lens MB, Newton-Bishop JA, Boon AP
Br J Dermatol 2005 Apr;152(4):673-8. doi: 10.1111/j.1365-2133.2005.06462.x. PMID: 15840097

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