U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Gallbladder Hyperplastic Polyp

MedGen UID:
232223
•Concept ID:
C1333743
•
Disease or Syndrome
Synonyms: Gallbladder Metaplastic Polyp; Hyperplastic Polyp of Gallbladder; Hyperplastic Polyp of the Gallbladder

Definition

A polypoid tumor that arises from the gallbladder. It is characterized by the presence of elongated, serrated crypts lined by proliferative epithelium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGallbladder Hyperplastic Polyp

Professional guidelines

PubMed

Dysplasia and carcinoma of the gallbladder: pathological evaluation, sampling, differential diagnosis and clinical implications.
Roa JC, Basturk O, Adsay V
Histopathology 2021 Jul;79(1):2-19. Epub 2021 May 6 doi: 10.1111/his.14360. PMID: 33629395

Recent clinical studies

Etiology

Histopathological Evaluation of Gallbladder Specimens Obtained From Living Liver Donors.
Akbulut S, Sarici KB, Toprak S, Tuncer A, Ciftci F, Karadag N, Gurluler E, Karabulut E, Colak C, Yilmaz S
Transplant Proc 2023 Jun;55(5):1267-1272. Epub 2023 Jan 4 doi: 10.1016/j.transproceed.2022.11.010. PMID: 36604250
Clinical Features and Outcomes of Gallbladder Polyps in Children.
Ferzeliyev O, Oğuz B, Soyer T, Boybey Türer Ö, Haliloglu M, Tanyel FC
Turk J Gastroenterol 2022 Sep;33(9):803-807. doi: 10.5152/tjg.2022.21944. PMID: 35946883Free PMC Article
Diagnostic accuracy of transabdominal ultrasonography for gallbladder polyps: systematic review.
Martin E, Gill R, Debru E
Can J Surg 2018 Jun;61(3):200-207. doi: 10.1503/cjs.011617. PMID: 29806818Free PMC Article
Gallbladder polyps: how should they be treated and when?
Matos AS, Baptista HN, Pinheiro C, Martinho F
Rev Assoc Med Bras (1992) 2010 May-Jun;56(3):318-21. doi: 10.1590/s0104-42302010000300017. PMID: 20676540
Benign tumors and pseudotumors of the gallbladder. Report of 180 cases.
Christensen AH, Ishak KG
Arch Pathol 1970 Nov;90(5):423-32. PMID: 4319984

Diagnosis

Clinical Features and Outcomes of Gallbladder Polyps in Children.
Ferzeliyev O, Oğuz B, Soyer T, Boybey Türer Ö, Haliloglu M, Tanyel FC
Turk J Gastroenterol 2022 Sep;33(9):803-807. doi: 10.5152/tjg.2022.21944. PMID: 35946883Free PMC Article
Dysplasia and carcinoma of the gallbladder: pathological evaluation, sampling, differential diagnosis and clinical implications.
Roa JC, Basturk O, Adsay V
Histopathology 2021 Jul;79(1):2-19. Epub 2021 May 6 doi: 10.1111/his.14360. PMID: 33629395
Diagnostic accuracy of transabdominal ultrasonography for gallbladder polyps: systematic review.
Martin E, Gill R, Debru E
Can J Surg 2018 Jun;61(3):200-207. doi: 10.1503/cjs.011617. PMID: 29806818Free PMC Article
Giant hyperplastic polyp of the gallbladder: a case report.
Kubota K, Bandai Y, Araki Y, Oka T, Makuuchi M
J Clin Ultrasound 1996 May;24(4):203-6. doi: 10.1002/(SICI)1097-0096(199605)24:4<203::AID-JCU7>3.0.CO;2-J. PMID: 8727419
Cholecystitis and the hyperplastic cholecystoses: a clinical, radiologic, and pathology study.
Lubera RJ, Climie AR, Kling GE
Am J Dig Dis 1967 Jul;12(7):696-704. doi: 10.1007/BF02238277. PMID: 4961260

Therapy

Histopathological Evaluation of Gallbladder Specimens Obtained From Living Liver Donors.
Akbulut S, Sarici KB, Toprak S, Tuncer A, Ciftci F, Karadag N, Gurluler E, Karabulut E, Colak C, Yilmaz S
Transplant Proc 2023 Jun;55(5):1267-1272. Epub 2023 Jan 4 doi: 10.1016/j.transproceed.2022.11.010. PMID: 36604250
Image of the month. Fundic gland polyps.
Obokhare I, Santoso S, Coughlan C, Ponsky J
Arch Surg 2012 Jun;147(6):575-6. doi: 10.1001/archsurg.147.6.576. PMID: 22786549
Benign tumors and pseudotumors of the gallbladder. Report of 180 cases.
Christensen AH, Ishak KG
Arch Pathol 1970 Nov;90(5):423-32. PMID: 4319984

Prognosis

Gallbladder polyps and adenomyomatosis.
Riddell ZC, Corallo C, Albazaz R, Foley KG
Br J Radiol 2023 Feb;96(1142):20220115. Epub 2022 Jul 1 doi: 10.1259/bjr.20220115. PMID: 35731858Free PMC Article
Roles of Adipokines in Digestive Diseases: Markers of Inflammation, Metabolic Alteration and Disease Progression.
Chang ML, Yang Z, Yang SS
Int J Mol Sci 2020 Nov 5;21(21) doi: 10.3390/ijms21218308. PMID: 33167521Free PMC Article
Diagnostic accuracy of transabdominal ultrasonography for gallbladder polyps: systematic review.
Martin E, Gill R, Debru E
Can J Surg 2018 Jun;61(3):200-207. doi: 10.1503/cjs.011617. PMID: 29806818Free PMC Article
Traditional serrated adenomas of the upper digestive tract.
Rubio CA
J Clin Pathol 2016 Jan;69(1):1-5. Epub 2015 Oct 14 doi: 10.1136/jclinpath-2015-203258. PMID: 26468393Free PMC Article
From the archives of the AFIP. Benign tumors and tumorlike lesions of the gallbladder and extrahepatic bile ducts: radiologic-pathologic correlation. Armed Forces Institute of Pathology.
Levy AD, Murakata LA, Abbott RM, Rohrmann CA Jr
Radiographics 2002 Mar-Apr;22(2):387-413. doi: 10.1148/radiographics.22.2.g02mr08387. PMID: 11896229

Clinical prediction guides

Diagnostic accuracy of transabdominal ultrasonography for gallbladder polyps: systematic review.
Martin E, Gill R, Debru E
Can J Surg 2018 Jun;61(3):200-207. doi: 10.1503/cjs.011617. PMID: 29806818Free PMC Article
A Retrospective Evaluation of the Epithelial Changes/Lesions and Neoplasms of the Gallbladder in Turkey and a Review of the Existing Sampling Methods: A Multicentre Study.
Esendağlı G, Akarca FG, Balcı S, Argon A, Erhan SŞ, Turhan N, Zengin Nİ, Keser SH, Çelik B, Bulut T, Abdullazade S, Erden E, Savaş B, Bostan T, Sağol Ö, Ağalar AA, Kepil N, Karslıoğlu Y, Günal A, Markoç F, Saka B, Özgün G, Özdamar ŞO, Bahadır B, Kaymaz E, Işık E, Ayhan S, Tunçel D, Yılmaz BÖ, Çelik S, Karabacak T, Seven İE, Çelikel ÇA, Gücin Z, Ekinci Ö, Akyol G
Turk Patoloji Derg 2018;34(1):41-48. doi: 10.5146/tjpath.2017.01404. PMID: 28984336
Contrast-enhanced ultrasound in diagnosis of gallbladder adenoma.
Yuan HX, Cao JY, Kong WT, Xia HS, Wang X, Wang WP
Hepatobiliary Pancreat Dis Int 2015 Apr;14(2):201-7. doi: 10.1016/s1499-3872(15)60351-4. PMID: 25865694
Correlation of S1P1 and ERp29 expression to progression, metastasis, and poor prognosis of gallbladder adenocarcinoma.
Yuan LW, Liu DC, Yang ZL
Hepatobiliary Pancreat Dis Int 2013 Apr;12(2):189-95. doi: 10.1016/s1499-3872(13)60030-2. PMID: 23558074
Identification of PEG10 and TSG101 as carcinogenesis, progression, and poor-prognosis related biomarkers for gallbladder adenocarcinoma.
Liu DC, Yang ZL, Jiang S
Pathol Oncol Res 2011 Dec;17(4):859-66. Epub 2011 Apr 1 doi: 10.1007/s12253-011-9394-7. PMID: 21455631

Recent systematic reviews

Diagnostic accuracy of transabdominal ultrasonography for gallbladder polyps: systematic review.
Martin E, Gill R, Debru E
Can J Surg 2018 Jun;61(3):200-207. doi: 10.1503/cjs.011617. PMID: 29806818Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...