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Ependymal tumor

MedGen UID:
232459
Concept ID:
C1333407
Neoplastic Process
Synonyms: Ependymal Neoplasm; ependymal neoplasm; Ependymal Tumor; ependymal tumor; ependymal tumors; ependymal tumours; ependymomal tumor; ependymomal tumour
 
Monarch Initiative: MONDO:0003266
Orphanet: ORPHA301

Definition

A tumor of neurectodermal origin arising from ependymal cells that line the ventricles and central canal of the spinal cord, that can occur in both children and adults, and that is characterized by wide a range of clinical manifestations depending on the location of the tumor, such as intracranial hypertension for tumors originating in the posterior fossa, behavioural changes and pyramidal signs for supratentorial tumors, and dysesthesia for tumors of the spinal cord. They can be classified as myxopapillary ependymoma, subependymoma, ependymoma (low grade tumors) or anaplastic ependymoma (grade III tumors). [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpendymal tumor

Professional guidelines

PubMed

Träger M, Schweizer L, Pérez E, Schmid S, Hain EG, Dittmayer C, Onken J, Fukuoka K, Ichimura K, Schüller U, Dührsen L, Müther M, Paulus W, Thomas C, Gutt-Will M, Schucht P, Maragkou T, Schittenhelm J, Eckert F, Niyazi M, Fleischmann DF, Dorostkar MM, Feyer P, May SA, Moskopp D, Badakhshi H, Radke C, Walter J, Ehret F, Capper D, Kaul D
Neuro Oncol 2023 Jul 6;25(7):1286-1298. doi: 10.1093/neuonc/noad030. PMID: 36734226Free PMC Article

Recent clinical studies

Etiology

Träger M, Schweizer L, Pérez E, Schmid S, Hain EG, Dittmayer C, Onken J, Fukuoka K, Ichimura K, Schüller U, Dührsen L, Müther M, Paulus W, Thomas C, Gutt-Will M, Schucht P, Maragkou T, Schittenhelm J, Eckert F, Niyazi M, Fleischmann DF, Dorostkar MM, Feyer P, May SA, Moskopp D, Badakhshi H, Radke C, Walter J, Ehret F, Capper D, Kaul D
Neuro Oncol 2023 Jul 6;25(7):1286-1298. doi: 10.1093/neuonc/noad030. PMID: 36734226Free PMC Article
Pérez-Ramírez M, García-Méndez A, Siordia-Reyes AG, Chavarría A, Gómez C, García-Hernández N
Clin Neurol Neurosurg 2019 Nov;186:105488. Epub 2019 Aug 12 doi: 10.1016/j.clineuro.2019.105488. PMID: 31505435
Xi S, Sai K, Hu W, Wang F, Chen Y, Wang J, Zeng J, Chen Z
BMC Cancer 2019 Jul 19;19(1):717. doi: 10.1186/s12885-019-5877-9. PMID: 31324163Free PMC Article
Takami T, Naito K, Yamagata T, Shimokawa N, Ohata K
Oper Neurosurg (Hagerstown) 2017 Dec 1;13(6):746-754. doi: 10.1093/ons/opx057. PMID: 29186607
Riemenschneider MJ, Reifenberger G
Adv Tech Stand Neurosurg 2010;35:35-64. doi: 10.1007/978-3-211-99481-8_2. PMID: 20102110

Diagnosis

Träger M, Schweizer L, Pérez E, Schmid S, Hain EG, Dittmayer C, Onken J, Fukuoka K, Ichimura K, Schüller U, Dührsen L, Müther M, Paulus W, Thomas C, Gutt-Will M, Schucht P, Maragkou T, Schittenhelm J, Eckert F, Niyazi M, Fleischmann DF, Dorostkar MM, Feyer P, May SA, Moskopp D, Badakhshi H, Radke C, Walter J, Ehret F, Capper D, Kaul D
Neuro Oncol 2023 Jul 6;25(7):1286-1298. doi: 10.1093/neuonc/noad030. PMID: 36734226Free PMC Article
Lehman NL
J Neurooncol 2023 Feb;161(3):425-439. Epub 2023 Jan 6 doi: 10.1007/s11060-022-04222-1. PMID: 36604386Free PMC Article
Pérez-Ramírez M, García-Méndez A, Siordia-Reyes AG, Chavarría A, Gómez C, García-Hernández N
Clin Neurol Neurosurg 2019 Nov;186:105488. Epub 2019 Aug 12 doi: 10.1016/j.clineuro.2019.105488. PMID: 31505435
Takami T, Naito K, Yamagata T, Shimokawa N, Ohata K
Oper Neurosurg (Hagerstown) 2017 Dec 1;13(6):746-754. doi: 10.1093/ons/opx057. PMID: 29186607
Riemenschneider MJ, Reifenberger G
Adv Tech Stand Neurosurg 2010;35:35-64. doi: 10.1007/978-3-211-99481-8_2. PMID: 20102110

Prognosis

Almatrafi FR, Aseeri AM, Alqahtani MF, Al Mulla L, Al-Jubran S, AlOmair MA, Alsalmi S, Al-Anazi R
Med Arch 2023 Apr;77(2):150-154. doi: 10.5455/medarh.2023.77.150-154. PMID: 37260799Free PMC Article
Träger M, Schweizer L, Pérez E, Schmid S, Hain EG, Dittmayer C, Onken J, Fukuoka K, Ichimura K, Schüller U, Dührsen L, Müther M, Paulus W, Thomas C, Gutt-Will M, Schucht P, Maragkou T, Schittenhelm J, Eckert F, Niyazi M, Fleischmann DF, Dorostkar MM, Feyer P, May SA, Moskopp D, Badakhshi H, Radke C, Walter J, Ehret F, Capper D, Kaul D
Neuro Oncol 2023 Jul 6;25(7):1286-1298. doi: 10.1093/neuonc/noad030. PMID: 36734226Free PMC Article
Lehman NL
J Neurooncol 2023 Feb;161(3):425-439. Epub 2023 Jan 6 doi: 10.1007/s11060-022-04222-1. PMID: 36604386Free PMC Article
Pérez-Ramírez M, García-Méndez A, Siordia-Reyes AG, Chavarría A, Gómez C, García-Hernández N
Clin Neurol Neurosurg 2019 Nov;186:105488. Epub 2019 Aug 12 doi: 10.1016/j.clineuro.2019.105488. PMID: 31505435
Xi S, Sai K, Hu W, Wang F, Chen Y, Wang J, Zeng J, Chen Z
BMC Cancer 2019 Jul 19;19(1):717. doi: 10.1186/s12885-019-5877-9. PMID: 31324163Free PMC Article

Clinical prediction guides

Träger M, Schweizer L, Pérez E, Schmid S, Hain EG, Dittmayer C, Onken J, Fukuoka K, Ichimura K, Schüller U, Dührsen L, Müther M, Paulus W, Thomas C, Gutt-Will M, Schucht P, Maragkou T, Schittenhelm J, Eckert F, Niyazi M, Fleischmann DF, Dorostkar MM, Feyer P, May SA, Moskopp D, Badakhshi H, Radke C, Walter J, Ehret F, Capper D, Kaul D
Neuro Oncol 2023 Jul 6;25(7):1286-1298. doi: 10.1093/neuonc/noad030. PMID: 36734226Free PMC Article
Pérez-Ramírez M, García-Méndez A, Siordia-Reyes AG, Chavarría A, Gómez C, García-Hernández N
Clin Neurol Neurosurg 2019 Nov;186:105488. Epub 2019 Aug 12 doi: 10.1016/j.clineuro.2019.105488. PMID: 31505435
Xi S, Sai K, Hu W, Wang F, Chen Y, Wang J, Zeng J, Chen Z
BMC Cancer 2019 Jul 19;19(1):717. doi: 10.1186/s12885-019-5877-9. PMID: 31324163Free PMC Article
Ortiz J, Otero A, Bengoechea O, Gonçalves J, Sousa P, Figols J, Bullón A
J Child Neurol 2008 Sep;23(9):1058-61. doi: 10.1177/0883073808314160. PMID: 18827270

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