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Liver and intrahepatic bile duct neoplasm

MedGen UID:
232599
Concept ID:
C1333976
Neoplastic Process
Synonyms: epithelial hepatic and intrahepatic bile duct neoplasm; Hepatic and Intrahepatic Bile Duct Neoplasm; hepatic and intrahepatic bile duct neoplasm; liver and intrahepatic bile duct epithelial neoplasm; Liver and Intrahepatic Bile Duct Neoplasm; liver and intrahepatic bile duct neoplasm; Liver Neoplasm; liver neoplasm; liver neoplasm (disease); liver tumor; liver tumour; neoplasm of liver; tumor of liver; tumour of liver
 
Monarch Initiative: MONDO:0024477

Definition

A benign or malignant neoplasm that affects the liver parenchyma or intrahepatic bile ducts. Representative examples of benign neoplasms include hepatocellular adenoma, and bile duct adenoma. Representative examples of malignant neoplasms include hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and lymphoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLiver and intrahepatic bile duct neoplasm

Professional guidelines

PubMed

Moris D, Palta M, Kim C, Allen PJ, Morse MA, Lidsky ME
CA Cancer J Clin 2023 Mar;73(2):198-222. Epub 2022 Oct 19 doi: 10.3322/caac.21759. PMID: 36260350
Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, Cristoferi L, Ciaccio A, Cortinovis DL, Invernizzi P, Massironi S
Ann Hepatol 2022 Sep-Oct;27(5):100737. Epub 2022 Jul 7 doi: 10.1016/j.aohep.2022.100737. PMID: 35809836
Rizvi S, Gores GJ
Gastroenterology 2013 Dec;145(6):1215-29. Epub 2013 Oct 15 doi: 10.1053/j.gastro.2013.10.013. PMID: 24140396Free PMC Article

Recent clinical studies

Etiology

Guedj N
Curr Oncol 2022 Dec 26;30(1):370-380. doi: 10.3390/curroncol30010030. PMID: 36661679Free PMC Article
Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, Cristoferi L, Ciaccio A, Cortinovis DL, Invernizzi P, Massironi S
Ann Hepatol 2022 Sep-Oct;27(5):100737. Epub 2022 Jul 7 doi: 10.1016/j.aohep.2022.100737. PMID: 35809836
Vogel A, Saborowski A
Digestion 2017;95(3):181-185. Epub 2017 Mar 14 doi: 10.1159/000454763. PMID: 28288474
Jhaveri KS, Hosseini-Nik H
J Magn Reson Imaging 2015 Nov;42(5):1165-79. Epub 2014 Dec 1 doi: 10.1002/jmri.24810. PMID: 25447417
Masuoka HC, Rosen CB
Clin Liver Dis 2011 Nov;15(4):699-715. doi: 10.1016/j.cld.2011.08.004. PMID: 22032524

Diagnosis

Mocchegiani F, Vincenzi P, Conte G, Nicolini D, Rossi R, Cacciaguerra AB, Vivarelli M
World J Gastroenterol 2023 Oct 14;29(38):5361-5373. doi: 10.3748/wjg.v29.i38.5361. PMID: 37900587Free PMC Article
Scott A, Wong P, Melstrom LG
Surgery 2023 Jul;174(1):113-115. Epub 2023 Mar 9 doi: 10.1016/j.surg.2023.01.019. PMID: 36906437
Guedj N
Curr Oncol 2022 Dec 26;30(1):370-380. doi: 10.3390/curroncol30010030. PMID: 36661679Free PMC Article
Komuta M
Clin Mol Hepatol 2022 Jul;28(3):396-407. Epub 2022 Jan 14 doi: 10.3350/cmh.2021.0287. PMID: 35032970Free PMC Article
Lamarca A, Edeline J, Goyal L
ESMO Open 2022 Feb;7(1):100378. Epub 2022 Jan 13 doi: 10.1016/j.esmoop.2021.100378. PMID: 35032765Free PMC Article

Therapy

Merters J, Lamarca A
J Hepatol 2023 Mar;78(3):652-657. Epub 2022 Nov 15 doi: 10.1016/j.jhep.2022.11.005. PMID: 36400328
Moris D, Palta M, Kim C, Allen PJ, Morse MA, Lidsky ME
CA Cancer J Clin 2023 Mar;73(2):198-222. Epub 2022 Oct 19 doi: 10.3322/caac.21759. PMID: 36260350
Bao X, Li Q, Chen J, Chen D, Ye C, Dai X, Wang Y, Li X, Rong X, Cheng F, Jiang M, Zhu Z, Ding Y, Sun R, Liu C, Huang L, Jin Y, Li B, Lu J, Wu W, Guo Y, Fu W, Langley SR, Tano V, Fang W, Guo T, Sheng J, Zhao P, Ruan J
Cancer Immunol Res 2022 Jul 1;10(7):811-828. doi: 10.1158/2326-6066.CIR-21-1101. PMID: 35604302
Soares KC, Jarnagin WR
Ann Surg Oncol 2021 Aug;28(8):4158-4170. Epub 2021 Apr 7 doi: 10.1245/s10434-021-09871-6. PMID: 33829358Free PMC Article
Ma L, Hernandez MO, Zhao Y, Mehta M, Tran B, Kelly M, Rae Z, Hernandez JM, Davis JL, Martin SP, Kleiner DE, Hewitt SM, Ylaya K, Wood BJ, Greten TF, Wang XW
Cancer Cell 2019 Oct 14;36(4):418-430.e6. Epub 2019 Oct 3 doi: 10.1016/j.ccell.2019.08.007. PMID: 31588021Free PMC Article

Prognosis

Mocchegiani F, Vincenzi P, Conte G, Nicolini D, Rossi R, Cacciaguerra AB, Vivarelli M
World J Gastroenterol 2023 Oct 14;29(38):5361-5373. doi: 10.3748/wjg.v29.i38.5361. PMID: 37900587Free PMC Article
Liu D, Heij LR, Czigany Z, Dahl E, Lang SA, Ulmer TF, Luedde T, Neumann UP, Bednarsch J
J Exp Clin Cancer Res 2022 Apr 7;41(1):127. doi: 10.1186/s13046-022-02340-2. PMID: 35392957Free PMC Article
Khan SA, Tavolari S, Brandi G
Liver Int 2019 May;39 Suppl 1:19-31. Epub 2019 Mar 24 doi: 10.1111/liv.14095. PMID: 30851228
Vogel A, Saborowski A
Digestion 2017;95(3):181-185. Epub 2017 Mar 14 doi: 10.1159/000454763. PMID: 28288474
Bergquist A, von Seth E
Best Pract Res Clin Gastroenterol 2015 Apr;29(2):221-32. Epub 2015 Feb 16 doi: 10.1016/j.bpg.2015.02.003. PMID: 25966423

Clinical prediction guides

Shang T, Jiang T, Lu T, Wang H, Cui X, Pan Y, Xu M, Pei M, Ding Z, Feng X, Lin Y, Li X, Tan Y, Feng F, Dong H, Wang H, Dong L
Front Immunol 2023;14:1166497. Epub 2023 May 10 doi: 10.3389/fimmu.2023.1166497. PMID: 37234171Free PMC Article
Beri N
Immunotherapy 2023 May;15(7):541-551. Epub 2023 Apr 25 doi: 10.2217/imt-2022-0288. PMID: 37096964
Scott A, Wong P, Melstrom LG
Surgery 2023 Jul;174(1):113-115. Epub 2023 Mar 9 doi: 10.1016/j.surg.2023.01.019. PMID: 36906437
Zen Y
Hum Pathol 2023 Feb;132:197-207. Epub 2022 Jun 11 doi: 10.1016/j.humpath.2022.06.001. PMID: 35697170
Liu D, Heij LR, Czigany Z, Dahl E, Lang SA, Ulmer TF, Luedde T, Neumann UP, Bednarsch J
J Exp Clin Cancer Res 2022 Apr 7;41(1):127. doi: 10.1186/s13046-022-02340-2. PMID: 35392957Free PMC Article

Recent systematic reviews

Zhou Z, Chen C, Han B, Wang Y, Liu Y, Liu Q, Xu X, Yin Y, Sun B
Pathol Res Pract 2023 Sep;249:154755. Epub 2023 Aug 9 doi: 10.1016/j.prp.2023.154755. PMID: 37651837
Frega G, Cossio FP, Banales JM, Cardinale V, Macias RIR, Braconi C, Lamarca A
Cells 2023 Aug 19;12(16) doi: 10.3390/cells12162098. PMID: 37626908Free PMC Article
Zhou M, Na R, Lai S, Guo Y, Shi J, Nie J, Zhang S, Wang Y, Zheng T
Cytokine 2023 Sep;169:156271. Epub 2023 Jun 16 doi: 10.1016/j.cyto.2023.156271. PMID: 37331095
van Keulen AM, Büttner S, Erdmann JI, Hagendoorn J, Hoogwater FJH, IJzermans JNM, Neumann UP, Polak WG, De Jonge J, Olthof PB, Koerkamp BG
Surgery 2023 Apr;173(4):973-982. Epub 2022 Dec 27 doi: 10.1016/j.surg.2022.11.027. PMID: 36577599
Clements O, Eliahoo J, Kim JU, Taylor-Robinson SD, Khan SA
J Hepatol 2020 Jan;72(1):95-103. Epub 2019 Sep 16 doi: 10.1016/j.jhep.2019.09.007. PMID: 31536748

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