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Malignant Breast Adenomyoepithelioma

MedGen UID:
233142
•Concept ID:
C1334564
•
Neoplastic Process
Synonyms: Breast Adenomyoepithelioma with Malignant Change; Malignant Adenomyoepithelioma of Breast; Malignant Adenomyoepithelioma of the Breast

Definition

An adenomyoepithelioma of the breast in which the epithelial, myoepithelial, or both components have undergone malignant transformation. Such cases may follow an aggressive clinical course, including recurrences and local and distant metastases. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Breast Adenomyoepithelioma

Professional guidelines

PubMed

Update on selective special types of breast neoplasms: Focusing on controversies, differential diagnosis, and molecular genetic advances.
Wei S
Semin Diagn Pathol 2022 Sep;39(5):367-379. Epub 2022 Mar 18 doi: 10.1053/j.semdp.2022.03.001. PMID: 35331622
Triple-negative breast carcinomas of low malignant potential: review on diagnostic criteria and differential diagnoses.
Cima L, Kaya H, Marchiò C, Nishimura R, Wen HY, Fabbri VP, Foschini MP
Virchows Arch 2022 Jan;480(1):109-126. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03174-7. PMID: 34458945Free PMC Article
Genotype-phenotype associations in breast pathology: Achievements of the past quarter century.
Muller KE, Marotti JD
Breast J 2020 Jun;26(6):1123-1131. Epub 2020 May 4 doi: 10.1111/tbj.13861. PMID: 32367572

Recent clinical studies

Etiology

Clinical characteristics and outcomes of benign, atypical, and malignant breast adenomyoepithelioma: a single institution's experience.
Wiens N, Hoffman DI, Huang CY, Nayak A, Tchou J
Am J Surg 2020 Apr;219(4):651-654. Epub 2019 Apr 1 doi: 10.1016/j.amjsurg.2019.03.026. PMID: 30982573

Diagnosis

Clinical characteristics and outcomes of benign, atypical, and malignant breast adenomyoepithelioma: a single institution's experience.
Wiens N, Hoffman DI, Huang CY, Nayak A, Tchou J
Am J Surg 2020 Apr;219(4):651-654. Epub 2019 Apr 1 doi: 10.1016/j.amjsurg.2019.03.026. PMID: 30982573

Prognosis

Clinical characteristics and outcomes of benign, atypical, and malignant breast adenomyoepithelioma: a single institution's experience.
Wiens N, Hoffman DI, Huang CY, Nayak A, Tchou J
Am J Surg 2020 Apr;219(4):651-654. Epub 2019 Apr 1 doi: 10.1016/j.amjsurg.2019.03.026. PMID: 30982573
A Case of Metastatic Malignant Breast Adenomyoepithelioma With a Codon-61 Mutation of HRAS.
Watanabe S, Otani T, Iwasa T, Takahama T, Takeda M, Sakai K, Nishio K, Ito A, Nakagawa K
Clin Breast Cancer 2019 Oct;19(5):e589-e592. Epub 2019 Jun 20 doi: 10.1016/j.clbc.2019.05.001. PMID: 31301988

Clinical prediction guides

Clinical characteristics and outcomes of benign, atypical, and malignant breast adenomyoepithelioma: a single institution's experience.
Wiens N, Hoffman DI, Huang CY, Nayak A, Tchou J
Am J Surg 2020 Apr;219(4):651-654. Epub 2019 Apr 1 doi: 10.1016/j.amjsurg.2019.03.026. PMID: 30982573

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