U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Malignant Submandibular Gland Mixed Tumor

MedGen UID:
233160
Concept ID:
C1334622
Neoplastic Process
Synonyms: Malignant Mixed Neoplasm of Submandibular Gland; Malignant Mixed Neoplasm of the Submandibular Gland; Malignant Mixed Tumor of Submandibular Gland; Malignant Mixed Tumor of the Submandibular Gland; Malignant Submandibular Gland Mixed Neoplasm

Definition

A malignant tumor arising from the submandibular gland. It includes carcinoma ex pleomorphic adenoma, a malignant epithelial tumor arising from a pre-existing pleomorphic adenoma and carcinosarcoma which is characterized by a mixture of malignant epithelial and sarcomatous elements. [from NCI]

Professional guidelines

PubMed

Jesberg P, Monzon A, Gitomer SA, Herrmann BW
Am J Otolaryngol 2023 Sep-Oct;44(5):103948. Epub 2023 Jun 8 doi: 10.1016/j.amjoto.2023.103948. PMID: 37352681
Luksic I, Mamic M, Suton P
Oral Surg Oral Med Oral Pathol Oral Radiol 2022 Sep;134(3):302-309. Epub 2022 Feb 4 doi: 10.1016/j.oooo.2022.01.023. PMID: 35428601
Lee RJ, Tan AP, Tong EL, Satyadev N, Christensen RE
JAMA Otolaryngol Head Neck Surg 2015 Oct;141(10):905-12. doi: 10.1001/jamaoto.2015.1745. PMID: 26378411

Recent clinical studies

Etiology

Jesberg P, Monzon A, Gitomer SA, Herrmann BW
Am J Otolaryngol 2023 Sep-Oct;44(5):103948. Epub 2023 Jun 8 doi: 10.1016/j.amjoto.2023.103948. PMID: 37352681
Wakely PE
Cancer Cytopathol 2022 Aug;130(8):595-608. Epub 2022 Mar 7 doi: 10.1002/cncy.22568. PMID: 35255198
Aro K, Valle J, Tarkkanen J, Mäkitie A, Atula T
Acta Otorhinolaryngol Ital 2019 Jun;39(3):156-161. doi: 10.14639/0392-100X-2307. PMID: 31131834Free PMC Article
Guraya SS, Prayson RA
Ann Diagn Pathol 2016 Aug;23:38-42. Epub 2016 Jun 4 doi: 10.1016/j.anndiagpath.2016.06.001. PMID: 27402223
Auclair PL, Ellis GL
Mod Pathol 1996 Jun;9(6):652-7. PMID: 8782203

Diagnosis

Jeong JS, Cho KJ, Kim D, Lee YS, Song JS
Pathol Res Pract 2021 Dec;228:153678. Epub 2021 Oct 29 doi: 10.1016/j.prp.2021.153678. PMID: 34781210
Guraya SS, Prayson RA
Ann Diagn Pathol 2016 Aug;23:38-42. Epub 2016 Jun 4 doi: 10.1016/j.anndiagpath.2016.06.001. PMID: 27402223
Lee RJ, Tan AP, Tong EL, Satyadev N, Christensen RE
JAMA Otolaryngol Head Neck Surg 2015 Oct;141(10):905-12. doi: 10.1001/jamaoto.2015.1745. PMID: 26378411
Bradley P, McClelland L, Mehta D
ORL J Otorhinolaryngol Relat Spec 2007;69(3):137-45. Epub 2007 Jan 30 doi: 10.1159/000099222. PMID: 17264529
Saunders JR Jr, Hirata RM, Jaques DA
Surg Clin North Am 1986 Feb;66(1):59-81. doi: 10.1016/s0039-6109(16)43829-6. PMID: 3003940

Therapy

Talwar A, Patel E, Tam M, Zhou F, Hu K, Persky M, Vaezi A, Jacobson A, Givi B
Otolaryngol Head Neck Surg 2023 Apr;168(4):775-781. Epub 2023 Jan 29 doi: 10.1177/01945998221120646. PMID: 35998038
Basset CA, Rappa F, Lentini VL, Barone R, Pitruzzella A, Unti E, Cappello F, Conway de Macario E, Macario AJL, Leone A
Acta Histochem 2021 Sep;123(6):151771. Epub 2021 Aug 19 doi: 10.1016/j.acthis.2021.151771. PMID: 34419757
Hu Y, Zheng C, Cao R, Hong W, Zhang Z
J Int Med Res 2020 Jan;48(1):300060519892783. doi: 10.1177/0300060519892783. PMID: 31971033Free PMC Article
Maharshi V, Nagar P
Indian J Pharmacol 2017 Jan-Feb;49(1):130-131. doi: 10.4103/0253-7613.201018. PMID: 28458439Free PMC Article
Sreerama L, Sladek NE
Arch Oral Biol 1996 Jun;41(6):597-605. doi: 10.1016/0003-9969(96)00005-2. PMID: 8937651

Prognosis

Jeong JS, Cho KJ, Kim D, Lee YS, Song JS
Pathol Res Pract 2021 Dec;228:153678. Epub 2021 Oct 29 doi: 10.1016/j.prp.2021.153678. PMID: 34781210
Gilbert MR, Sharma A, Schmitt NC, Johnson JT, Ferris RL, Duvvuri U, Kim S
JAMA Otolaryngol Head Neck Surg 2016 May 1;142(5):489-95. doi: 10.1001/jamaoto.2015.3930. PMID: 26939990Free PMC Article
Wang C, Zhang Z, Ge Y, Liu Z, Sun J, Gao Z, Li L
J Oral Maxillofac Surg 2015 Oct;73(10):1938-45. Epub 2015 Apr 1 doi: 10.1016/j.joms.2015.03.054. PMID: 25896567
Auclair PL, Ellis GL
Mod Pathol 1996 Jun;9(6):652-7. PMID: 8782203
Fitzpatrick PJ, Theriault C
Int J Radiat Oncol Biol Phys 1986 Oct;12(10):1743-7. doi: 10.1016/0360-3016(86)90314-7. PMID: 3759525

Clinical prediction guides

Jesberg P, Monzon A, Gitomer SA, Herrmann BW
Am J Otolaryngol 2023 Sep-Oct;44(5):103948. Epub 2023 Jun 8 doi: 10.1016/j.amjoto.2023.103948. PMID: 37352681
Olejniczak I, Leduchowska A, Kozłowski Z, Pietruszewska W
Otolaryngol Pol 2021 Apr 20;75(4):7-13. doi: 10.5604/01.3001.0014.7889. PMID: 34344837
Wang C, Yu Q, Li S, Sun J, Zhu L, Wang P
Dentomaxillofac Radiol 2021 Oct 1;50(7):20200485. Epub 2021 Jun 23 doi: 10.1259/dmfr.20200485. PMID: 34161740Free PMC Article
Wang C, Zhang Z, Ge Y, Liu Z, Sun J, Gao Z, Li L
J Oral Maxillofac Surg 2015 Oct;73(10):1938-45. Epub 2015 Apr 1 doi: 10.1016/j.joms.2015.03.054. PMID: 25896567
Wright JD, Font RL
Cancer 1979 Nov;44(5):1757-68. doi: 10.1002/1097-0142(197911)44:5<1757::aid-cncr2820440533>3.0.co;2-8. PMID: 227576

Recent systematic reviews

Palicelli A
APMIS 2020 Mar;128(3):191-200. Epub 2020 Jan 3 doi: 10.1111/apm.13009. PMID: 31697865

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...