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Uterine body mixed cancer

MedGen UID:
233163
•Concept ID:
C1334628
•
Neoplastic Process
Synonyms: Malignant Body of Uterus Mixed Neoplasm; malignant body of uterus mixed neoplasm; Malignant Body of Uterus Mixed Tumor; malignant body of uterus mixed tumor; malignant body of uterus mixed tumour; Malignant Corpus Uteri Mixed Neoplasm; malignant corpus uteri mixed neoplasm; Malignant Corpus Uteri Mixed Tumor; malignant corpus uteri mixed tumor; malignant corpus uteri mixed tumour; Malignant Mixed Neoplasm of Body of Uterus; malignant mixed neoplasm of body of uterus; Malignant Mixed Neoplasm of Corpus Uteri; malignant mixed neoplasm of corpus uteri; Malignant Mixed Neoplasm of the Body of Uterus; malignant mixed neoplasm of the body of uterus; Malignant Mixed Neoplasm of the Corpus Uteri; malignant mixed neoplasm of the corpus uteri; Malignant Mixed Neoplasm of the Uterine Body; malignant mixed neoplasm of the uterine body; Malignant Mixed Neoplasm of the Uterine Corpus; malignant mixed neoplasm of the uterine corpus; Malignant Mixed Neoplasm of Uterine Body; malignant mixed neoplasm of uterine body; Malignant Mixed Neoplasm of Uterine Corpus; malignant mixed neoplasm of uterine corpus; Malignant Mixed Tumor of Body of Uterus; malignant mixed tumor of body of uterus; Malignant Mixed Tumor of Corpus Uteri; malignant mixed tumor of corpus uteri; Malignant Mixed Tumor of the Body of Uterus; malignant mixed tumor of the body of uterus; Malignant Mixed Tumor of the Corpus Uteri; malignant mixed tumor of the corpus uteri; Malignant Mixed Tumor of the Uterine Body; malignant mixed tumor of the uterine body; Malignant Mixed Tumor of the Uterine Corpus; malignant mixed tumor of the uterine corpus; Malignant Mixed Tumor of Uterine Body; malignant mixed tumor of uterine body; Malignant Mixed Tumor of Uterine Corpus; malignant mixed tumor of uterine corpus; malignant mixed tumour of body of uterus; malignant mixed tumour of corpus uteri; malignant mixed tumour of the body of uterus; malignant mixed tumour of the corpus uteri; malignant mixed tumour of the uterine body; malignant mixed tumour of the uterine corpus; malignant mixed tumour of uterine body; malignant mixed tumour of uterine corpus; Malignant Uterine Body Mixed Neoplasm; malignant uterine body mixed neoplasm; Malignant Uterine Body Mixed Tumor; malignant uterine body mixed tumor; malignant uterine body mixed tumour; Malignant Uterine Corpus Mixed Epithelial and Mesenchymal Neoplasm; malignant uterine corpus mixed epithelial and mesenchymal neoplasm; Malignant Uterine Corpus Mixed Tumor; malignant uterine corpus mixed tumor; malignant uterine corpus mixed tumour; uterine body mixed cancer
 
Monarch Initiative: MONDO:0002879

Definition

A primary malignant neoplasm of the uterine corpus characterized by the presence of an epithelial and a mesenchymal component. This category includes carcinosarcoma, carcinofibroma, and adenosarcoma. [from NCI]

Professional guidelines

PubMed

Uterine fibroid management: Today and tomorrow.
Dolmans MM, Donnez J, Fellah L
J Obstet Gynaecol Res 2019 Jul;45(7):1222-1229. Epub 2019 May 29 doi: 10.1111/jog.14002. PMID: 31141843

Recent clinical studies

Etiology

Urinary phytoestrogens and the risk of uterine leiomyomata in US women.
Yang F, Chen Y
BMC Womens Health 2023 May 13;23(1):261. doi: 10.1186/s12905-023-02381-5. PMID: 37179289Free PMC Article
Dietary omega-3 fatty acids and endometrial cancer risk in the Epidemiology of Endometrial Cancer Consortium: An individual-participant meta-analysis.
Brasky TM, Hade EM, Cohn DE, Newton AM, Petruzella S, O'Connell K, Bertrand KA, Cook LS, De Vivo I, Du M, Freudenheim JL, Friedenreich CM, Goodman MT, Gorzelitz J, Ibiebele TI, Krogh V, Liao LM, Lipworth L, Lu L, McCann S, O'Mara TA, Palmer JR, Ponte J, Prizment A, Risch H, Sandin S, Schouten LJ, Setiawan VW, Shu XO, Trabert B, van den Brandt PA, Webb PM, Wentzensen N, Wilkens LR, Wolk A, Yu H, Neuhouser ML
Gynecol Oncol 2023 Feb;169:137-146. Epub 2022 Oct 28 doi: 10.1016/j.ygyno.2022.10.015. PMID: 36934308Free PMC Article
Vitamin D and uterine fibroid growth, incidence, and loss: a prospective ultrasound study.
Harmon QE, Patchel SA, Denslow S, LaPorte F, Cooper T, Wise LA, Wegienka G, Baird DD
Fertil Steril 2022 Dec;118(6):1127-1136. Epub 2022 Sep 21 doi: 10.1016/j.fertnstert.2022.08.851. PMID: 36150919Free PMC Article
Body size and composition and risk of site-specific cancers in the UK Biobank and large international consortia: A mendelian randomisation study.
Vithayathil M, Carter P, Kar S, Mason AM, Burgess S, Larsson SC
PLoS Med 2021 Jul;18(7):e1003706. Epub 2021 Jul 29 doi: 10.1371/journal.pmed.1003706. PMID: 34324486Free PMC Article
Obesity and screening for breast, cervical, and colorectal cancer in women: a review.
Cohen SS, Palmieri RT, Nyante SJ, Koralek DO, Kim S, Bradshaw P, Olshan AF
Cancer 2008 May 1;112(9):1892-904. doi: 10.1002/cncr.23408. PMID: 18361400

Diagnosis

Vitamin D and uterine fibroid growth, incidence, and loss: a prospective ultrasound study.
Harmon QE, Patchel SA, Denslow S, LaPorte F, Cooper T, Wise LA, Wegienka G, Baird DD
Fertil Steril 2022 Dec;118(6):1127-1136. Epub 2022 Sep 21 doi: 10.1016/j.fertnstert.2022.08.851. PMID: 36150919Free PMC Article
"A lot can happen in five years": Women's attitudes to extending cervical screening intervals.
Kola-Palmer S, Rogers M, Halliday A, Rickford R
Eur J Cancer Care (Engl) 2022 Nov;31(6):e13655. Epub 2022 Jul 15 doi: 10.1111/ecc.13655. PMID: 35838304Free PMC Article
'I thought I had fibroids, and now I don't': a mixed method study on health-related quality of life in uterine sarcoma patients.
den Hollander D, Lidington E, Singer S, Sodergren SC, Salah S, Fiore M, Benson C, Desar IME, Burgers VWG, Husson O, van der Graaf WTA
Health Qual Life Outcomes 2022 Apr 20;20(1):65. doi: 10.1186/s12955-022-01971-5. PMID: 35443673Free PMC Article
Obesity and screening for breast, cervical, and colorectal cancer in women: a review.
Cohen SS, Palmieri RT, Nyante SJ, Koralek DO, Kim S, Bradshaw P, Olshan AF
Cancer 2008 May 1;112(9):1892-904. doi: 10.1002/cncr.23408. PMID: 18361400
Uterine neoplasms: MR imaging.
Worthington JL, Balfe DM, Lee JK, Gersell DJ, Heiken JP, Ling D, Glazer HS, Jacobs AJ, Kao MS, McClennan BL
Radiology 1986 Jun;159(3):725-30. doi: 10.1148/radiology.159.3.3010375. PMID: 3010375

Therapy

Effects of different types of hysterectomies on postoperative urodynamics and lower urinary tract symptoms.
Shin JH, Gwak CH, Park MU, Choo MS
Investig Clin Urol 2022 Mar;63(2):207-213. doi: 10.4111/icu.20210393. PMID: 35244995Free PMC Article
Population Pharmacokinetics of Elagolix in Combination with Low-Dose Estradiol/Norethindrone Acetate in Women with Uterine Fibroids.
Beck D, Winzenborg I, Liu M, Degner J, Mostafa NM, Noertersheuser P, Shebley M
Clin Pharmacokinet 2022 Apr;61(4):577-587. Epub 2021 Dec 8 doi: 10.1007/s40262-021-01096-w. PMID: 34878624Free PMC Article
Body size and composition and risk of site-specific cancers in the UK Biobank and large international consortia: A mendelian randomisation study.
Vithayathil M, Carter P, Kar S, Mason AM, Burgess S, Larsson SC
PLoS Med 2021 Jul;18(7):e1003706. Epub 2021 Jul 29 doi: 10.1371/journal.pmed.1003706. PMID: 34324486Free PMC Article
Insufficient Leiomyoma Infarction in Uterine Artery Embolization: Relationship with Tumor Location.
Katsumori T, Yoshikawa T, Miura H
J Vasc Interv Radiol 2019 May;30(5):668-675.e1. Epub 2019 Apr 2 doi: 10.1016/j.jvir.2018.11.041. PMID: 30952521
Survivors of uterine cancer empowered by exercise and healthy diet (SUCCEED): a randomized controlled trial.
von Gruenigen V, Frasure H, Kavanagh MB, Janata J, Waggoner S, Rose P, Lerner E, Courneya KS
Gynecol Oncol 2012 Jun;125(3):699-704. Epub 2012 Mar 28 doi: 10.1016/j.ygyno.2012.03.042. PMID: 22465522

Prognosis

Religious and traditional beliefs and practices as predictors of mental and physical health outcomes and the role of religious affiliation in health outcomes and risk taking.
Wüthrich-Grossenbacher U, Midzi N, Mutsaka-Makuvaza MJ, Mutsinze A
BMC Public Health 2023 Nov 6;23(1):2170. doi: 10.1186/s12889-023-17030-7. PMID: 37932702Free PMC Article
Body size and composition and risk of site-specific cancers in the UK Biobank and large international consortia: A mendelian randomisation study.
Vithayathil M, Carter P, Kar S, Mason AM, Burgess S, Larsson SC
PLoS Med 2021 Jul;18(7):e1003706. Epub 2021 Jul 29 doi: 10.1371/journal.pmed.1003706. PMID: 34324486Free PMC Article
MDCT evaluation of synchronous breast carcinoma and other solid malignancies.
El-Badrawy A
Breast Dis 2021;40(4):275-281. doi: 10.3233/BD-201065. PMID: 34120894
Insufficient Leiomyoma Infarction in Uterine Artery Embolization: Relationship with Tumor Location.
Katsumori T, Yoshikawa T, Miura H
J Vasc Interv Radiol 2019 May;30(5):668-675.e1. Epub 2019 Apr 2 doi: 10.1016/j.jvir.2018.11.041. PMID: 30952521
Paratesticular mesothelial proliferations.
Churg A
Semin Diagn Pathol 2003 Nov;20(4):272-8. doi: 10.1053/j.semdp.2003.08.003. PMID: 14694980

Clinical prediction guides

Cancer in Ecuadorian subjects with Laron syndrome (ELS).
Guevara-Aguirre J, Peña G, Pazmiño G, Acosta W, Saavedra J, Lescano D, Guevara A, Gavilanes AWD
Endocr Relat Cancer 2023 Jun 1;30(6) Epub 2023 May 11 doi: 10.1530/ERC-22-0389. PMID: 36971780
Dietary omega-3 fatty acids and endometrial cancer risk in the Epidemiology of Endometrial Cancer Consortium: An individual-participant meta-analysis.
Brasky TM, Hade EM, Cohn DE, Newton AM, Petruzella S, O'Connell K, Bertrand KA, Cook LS, De Vivo I, Du M, Freudenheim JL, Friedenreich CM, Goodman MT, Gorzelitz J, Ibiebele TI, Krogh V, Liao LM, Lipworth L, Lu L, McCann S, O'Mara TA, Palmer JR, Ponte J, Prizment A, Risch H, Sandin S, Schouten LJ, Setiawan VW, Shu XO, Trabert B, van den Brandt PA, Webb PM, Wentzensen N, Wilkens LR, Wolk A, Yu H, Neuhouser ML
Gynecol Oncol 2023 Feb;169:137-146. Epub 2022 Oct 28 doi: 10.1016/j.ygyno.2022.10.015. PMID: 36934308Free PMC Article
Body size and composition and risk of site-specific cancers in the UK Biobank and large international consortia: A mendelian randomisation study.
Vithayathil M, Carter P, Kar S, Mason AM, Burgess S, Larsson SC
PLoS Med 2021 Jul;18(7):e1003706. Epub 2021 Jul 29 doi: 10.1371/journal.pmed.1003706. PMID: 34324486Free PMC Article
Obesity and screening for breast, cervical, and colorectal cancer in women: a review.
Cohen SS, Palmieri RT, Nyante SJ, Koralek DO, Kim S, Bradshaw P, Olshan AF
Cancer 2008 May 1;112(9):1892-904. doi: 10.1002/cncr.23408. PMID: 18361400
Body size in relation to cancer of the uterine corpus in 1 million Norwegian women.
Bjørge T, Engeland A, Tretli S, Weiderpass E
Int J Cancer 2007 Jan 15;120(2):378-83. doi: 10.1002/ijc.22260. PMID: 17066451

Recent systematic reviews

Evidence on the prevalence, incidence, mortality and trends of human papilloma virus-associated cancers in sub-Saharan Africa: systematic scoping review.
Lekoane KMB, Kuupiel D, Mashamba-Thompson TP, Ginindza TG
BMC Cancer 2019 Jun 11;19(1):563. doi: 10.1186/s12885-019-5781-3. PMID: 31185951Free PMC Article
Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action.
Pecquet AM, Martinez JM, Vincent M, Erraguntla N, Dourson M
J Appl Toxicol 2018 Jun;38(6):862-878. Epub 2018 Feb 13 doi: 10.1002/jat.3594. PMID: 29441599Free PMC Article

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