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Mediastinal Mixed Embryonal Carcinoma and Teratoma

MedGen UID:
233172
Concept ID:
C1334670
Neoplastic Process
Synonyms: Mediastinal Teratocarcinoma; Mixed Embryonal Carcinoma and Teratoma of Mediastinum; Mixed Embryonal Carcinoma and Teratoma of the Mediastinum; Teratocarcinoma of Mediastinum; Teratocarcinoma of the Mediastinum

Definition

An extragonadal non-seminomatous malignant germ cell tumor that arises from the mediastinum and contains teratoma and embryonal carcinoma components. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMediastinal Mixed Embryonal Carcinoma and Teratoma

Professional guidelines

PubMed

Yang X, Zhao K, Mei J, Wei S, Xia L, Pu Y, Liu L
J Surg Res 2021 Nov;267:25-36. Epub 2021 Jun 11 doi: 10.1016/j.jss.2021.04.022. PMID: 34126390
Rougemont AL, Tille JC
Hum Pathol 2018 Nov;81:26-36. Epub 2018 May 16 doi: 10.1016/j.humpath.2018.04.025. PMID: 29753846
McKenney JK, Heerema-McKenney A, Rouse RV
Adv Anat Pathol 2007 Mar;14(2):69-92. doi: 10.1097/PAP.0b013e31803240e6. PMID: 17471115

Recent clinical studies

Etiology

Wu P, Yang Y, Yu Z, Zhao L, Feng S
J Surg Res 2023 Aug;288:362-371. Epub 2023 Apr 14 doi: 10.1016/j.jss.2023.03.018. PMID: 37062232
Yang X, Zhao K, Mei J, Wei S, Xia L, Pu Y, Liu L
J Surg Res 2021 Nov;267:25-36. Epub 2021 Jun 11 doi: 10.1016/j.jss.2021.04.022. PMID: 34126390
Yalçın B, Demir HA, Tanyel FC, Akçören Z, Varan A, Akyüz C, Kutluk T, Büyükpamukçu M
Pediatr Hematol Oncol 2012 Oct;29(7):633-42. Epub 2012 Aug 9 doi: 10.3109/08880018.2012.713084. PMID: 22877235
McKenney JK, Heerema-McKenney A, Rouse RV
Adv Anat Pathol 2007 Mar;14(2):69-92. doi: 10.1097/PAP.0b013e31803240e6. PMID: 17471115
Woodward PJ, Sohaey R, O'Donoghue MJ, Green DE
Radiographics 2002 Jan-Feb;22(1):189-216. doi: 10.1148/radiographics.22.1.g02ja14189. PMID: 11796908

Diagnosis

Ren C, Zhao J, Kang L, Di Y, Qiu G, Wang Q
Medicine (Baltimore) 2021 Oct 29;100(43):e27617. doi: 10.1097/MD.0000000000027617. PMID: 34713845Free PMC Article
El-Zaatari ZM, Ro JY
Adv Anat Pathol 2021 Sep 1;28(5):335-350. doi: 10.1097/PAP.0000000000000304. PMID: 34029275
Yalçın B, Demir HA, Tanyel FC, Akçören Z, Varan A, Akyüz C, Kutluk T, Büyükpamukçu M
Pediatr Hematol Oncol 2012 Oct;29(7):633-42. Epub 2012 Aug 9 doi: 10.3109/08880018.2012.713084. PMID: 22877235
Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ Jr
Radiographics 2002 Oct;22 Spec No:S61-78. doi: 10.1148/radiographics.22.suppl_1.g02oc08s61. PMID: 12376601
Weidner N
Semin Diagn Pathol 1999 Feb;16(1):42-50. PMID: 10355653

Therapy

Ren C, Zhao J, Kang L, Di Y, Qiu G, Wang Q
Medicine (Baltimore) 2021 Oct 29;100(43):e27617. doi: 10.1097/MD.0000000000027617. PMID: 34713845Free PMC Article
Detti B, Livi L, Scoccianti S, Meattini I, Gacci M, Lapini A, Biti G
Tumori 2007 Sep-Oct;93(5):428-31. doi: 10.1177/030089160709300504. PMID: 18038873
Mardiak J, Sálek T, Sycová-Milá Z, Obertová J, Recková M, Mego M, Hlavatá Z, Brozmanová K, Risnyovzská Z, Svetlovská D, Koza I
Neoplasma 2007;54(3):240-5. PMID: 17447857
Gerl A, Clemm C, Schmeller N, Hentrich M, Lamerz R, Wilmanns W
Ann Oncol 1997 Jan;8(1):41-7. doi: 10.1023/a:1008253323854. PMID: 9093706
Cox JD
Cancer 1975 Sep;36(3):1162-8. doi: 10.1002/1097-0142(197509)36:3<1162::aid-cncr2820360351>3.0.co;2-0. PMID: 1237349

Prognosis

Wu P, Yang Y, Yu Z, Zhao L, Feng S
J Surg Res 2023 Aug;288:362-371. Epub 2023 Apr 14 doi: 10.1016/j.jss.2023.03.018. PMID: 37062232
Ren C, Zhao J, Kang L, Di Y, Qiu G, Wang Q
Medicine (Baltimore) 2021 Oct 29;100(43):e27617. doi: 10.1097/MD.0000000000027617. PMID: 34713845Free PMC Article
Yang X, Zhao K, Mei J, Wei S, Xia L, Pu Y, Liu L
J Surg Res 2021 Nov;267:25-36. Epub 2021 Jun 11 doi: 10.1016/j.jss.2021.04.022. PMID: 34126390
Weidner N
Semin Diagn Pathol 1999 Feb;16(1):42-50. PMID: 10355653
Moran CA, Travis WD, Carter D, Koss MN
Arch Pathol Lab Med 1993 Jun;117(6):641-4. PMID: 8135909

Clinical prediction guides

Yang X, Zhao K, Mei J, Wei S, Xia L, Pu Y, Liu L
J Surg Res 2021 Nov;267:25-36. Epub 2021 Jun 11 doi: 10.1016/j.jss.2021.04.022. PMID: 34126390
Rougemont AL, Tille JC
Hum Pathol 2018 Nov;81:26-36. Epub 2018 May 16 doi: 10.1016/j.humpath.2018.04.025. PMID: 29753846
Xiao GQ, Li F, Unger PD, Katerji H, Yang Q, McMahon L, Burstein DE
Mod Pathol 2016 Jun;29(6):591-8. Epub 2016 Feb 26 doi: 10.1038/modpathol.2016.46. PMID: 26916077
McKenney JK, Heerema-McKenney A, Rouse RV
Adv Anat Pathol 2007 Mar;14(2):69-92. doi: 10.1097/PAP.0b013e31803240e6. PMID: 17471115
Woodward PJ, Sohaey R, O'Donoghue MJ, Green DE
Radiographics 2002 Jan-Feb;22(1):189-216. doi: 10.1148/radiographics.22.1.g02ja14189. PMID: 11796908

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