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Mixed hepatoblastoma

MedGen UID:
233194
•Concept ID:
C1334784
•
Neoplastic Process
Synonyms: Hepatoblastoma, mixed epithelial-mesenchymal; Mixed Epithelial and Mesenchymal Hepatoblastoma; mixed epithelial and mesenchymal hepatoblastoma; Mixed epithelial-mesenchymal hepatoblastoma; mixed hepatoblastoma
SNOMED CT: Hepatoblastoma, mixed epithelial-mesenchymal (734033006); Mixed epithelial-mesenchymal hepatoblastoma (734033006)
 
Monarch Initiative: MONDO:0003650

Definition

A subtype of hepatoblastoma characterized by the presence of epithelial and mesenchymal components. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMixed hepatoblastoma

Professional guidelines

PubMed

Navigating relapsed hepatoblastoma: Predictive factors and surgical treatment strategy.
Espinoza AF, Patel KR, Shetty PB, Whitlock RS, Sumazin P, Yu X, Sarabia SF, Urbicain M, Heczey A, Masand P, Woodfield SE, López-Terrada DH, Vasudevan SA
Cancer Med 2023 Dec;12(23):21270-21278. Epub 2023 Nov 14 doi: 10.1002/cam4.6705. PMID: 37962078Free PMC Article
Diagnosis, histopathologic correlation and management of hepatoblastoma: What the radiologist needs to know.
Baheti AD, Chapman T, Rudzinski E, Albert CM, Stanescu AL
Clin Imaging 2018 Nov-Dec;52:273-279. Epub 2018 Aug 18 doi: 10.1016/j.clinimag.2018.08.009. PMID: 30172849
Changing treatment and outcome of children with hepatoblastoma: analysis of a single center experience over the last 20 years.
Ismail H, Broniszczak D, Kaliciński P, Dembowska-Bagińska B, Perek D, Teisseyre J, Kluge P, Kościesza A, Lembas A, Markiewicz M
J Pediatr Surg 2012 Jul;47(7):1331-9. doi: 10.1016/j.jpedsurg.2011.11.073. PMID: 22813792

Recent clinical studies

Etiology

Hepatoblastoma in adult age. A case report and literature review.
Remes-Troche JM, Montaño-Loza A, Meza-Junco J, García-Leiva J, Torre-Delgadillo A
Ann Hepatol 2006 Jul-Sep;5(3):179-81. PMID: 17060878
Epithelial and mixed hepatoblastoma in the adult. Histological observations and general considerations.
Altmann HW
Pathol Res Pract 1992 Feb;188(1-2):16-26. doi: 10.1016/s0344-0338(11)81151-9. PMID: 1317555

Diagnosis

Growing teratoma syndrome in mixed hepatoblastoma with teratoid features.
Khera S, Singh V, Parikh B, Chand K
BMJ Case Rep 2021 Mar 17;14(3) doi: 10.1136/bcr-2020-241197. PMID: 33731392Free PMC Article
Mixed hepatoblastoma in an adult.
Kasper HU, Longerich T, Stippel DL, Kern MA, Drebber U, Schirmacher P
Arch Pathol Lab Med 2005 Feb;129(2):234-7. doi: 10.5858/2005-129-234-MHIAA. PMID: 15679429
Mixed hepatoblastoma in an adult--a case report and literature review.
Ahn HJ, Kwon KW, Choi YJ, Kim HJ, Hong SP, Oh D, Chung JS
J Korean Med Sci 1997 Aug;12(4):369-73. doi: 10.3346/jkms.1997.12.4.369. PMID: 9288639Free PMC Article
Epithelial and mixed hepatoblastoma in the adult. Histological observations and general considerations.
Altmann HW
Pathol Res Pract 1992 Feb;188(1-2):16-26. doi: 10.1016/s0344-0338(11)81151-9. PMID: 1317555
Mixed hepatoblastoma in the adult: case report and review of the literature.
Honan RP, Haqqani MT
J Clin Pathol 1980 Nov;33(11):1058-63. doi: 10.1136/jcp.33.11.1058. PMID: 6255014Free PMC Article

Therapy

The effect of chemotherapy on hepatoblastoma.
Forouhar FA, Quinn JJ, Cooke R, Foster JH
Arch Pathol Lab Med 1984 Apr;108(4):311-4. PMID: 6322723

Prognosis

Hepatoblastoma in adult age. A case report and literature review.
Remes-Troche JM, Montaño-Loza A, Meza-Junco J, García-Leiva J, Torre-Delgadillo A
Ann Hepatol 2006 Jul-Sep;5(3):179-81. PMID: 17060878
Mixed hepatoblastoma in an adult--a case report and literature review.
Ahn HJ, Kwon KW, Choi YJ, Kim HJ, Hong SP, Oh D, Chung JS
J Korean Med Sci 1997 Aug;12(4):369-73. doi: 10.3346/jkms.1997.12.4.369. PMID: 9288639Free PMC Article

Clinical prediction guides

Recurrence of hepatocellular carcinoma as a mixed hepatoblastoma after liver transplantation.
Dumortier J, Bizollon T, Chevallier M, Ducerf C, Baulieux J, Scoazec JY, Trepo C
Gut 1999 Oct;45(4):622-5. doi: 10.1136/gut.45.4.622. PMID: 10486376Free PMC Article
Epithelial and mixed hepatoblastoma in the adult. Histological observations and general considerations.
Altmann HW
Pathol Res Pract 1992 Feb;188(1-2):16-26. doi: 10.1016/s0344-0338(11)81151-9. PMID: 1317555
Mixed hepatoblastoma in the adult: morphological and immunohistochemical findings.
Slugen I, Fiala P, Pauer M, Majercík M, Ondrias F, Cernák P
Bratisl Lek Listy 1990 Jul;91(7):507-15. PMID: 1698519

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