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Non-Neoplastic Breast Disorder

MedGen UID:
233231
•Concept ID:
C1334998
•
Disease or Syndrome
Synonyms: Non-Neoplastic Breast Disease; Non-Neoplastic Disease of Breast; Non-Neoplastic Disease of the Breast

Definition

A non-neoplastic disorder that affects the breast. Representative examples include fibrocystic disease, gynecomastia, mastitis, and adenosis. [from NCI]

Professional guidelines

PubMed

Cost in the United States of FDA-approved small molecule protein kinase inhibitors used in the treatment of neoplastic and non-neoplastic diseases.
Roskoski R Jr
Pharmacol Res 2024 Jan;199:107036. Epub 2023 Dec 12 doi: 10.1016/j.phrs.2023.107036. PMID: 38096958
Oral contraceptives, menopausal hormone replacement treatment and breast cancer risk.
Levi F, Lucchini F, Pasche C, La Vecchia C
Eur J Cancer Prev 1996 Aug;5(4):259-66. doi: 10.1097/00008469-199608000-00006. PMID: 8894563
Hormone replacement treatment and breast cancer risk: a cooperative Italian study.
La Vecchia C, Negri E, Franceschi S, Favero A, Nanni O, Filiberti R, Conti E, Montella M, Veronesi A, Ferraroni M
Br J Cancer 1995 Jul;72(1):244-8. doi: 10.1038/bjc.1995.310. PMID: 7599060Free PMC Article

Recent clinical studies

Etiology

INFLUENCE OF IONIZING RADIATION ON THE DEVELOPMENT OF BREAST CANCER.
Bazyka DA, Lytvynenko OO, Litvinenko OO
Probl Radiac Med Radiobiol 2023 Dec;28:22-48. doi: 10.33145/2304-8336-2023-28-22-48. PMID: 38155113
Metabolic pathways in obesity-related breast cancer.
Brown KA
Nat Rev Endocrinol 2021 Jun;17(6):350-363. Epub 2021 Apr 29 doi: 10.1038/s41574-021-00487-0. PMID: 33927368Free PMC Article
Mediterranean Diet and Breast Cancer Risk.
Turati F, Carioli G, Bravi F, Ferraroni M, Serraino D, Montella M, Giacosa A, Toffolutti F, Negri E, Levi F, La Vecchia C
Nutrients 2018 Mar 8;10(3) doi: 10.3390/nu10030326. PMID: 29518016Free PMC Article
How to approach breast lesions in children and adolescents.
Gao Y, Saksena MA, Brachtel EF, terMeulen DC, Rafferty EA
Eur J Radiol 2015 Jul;84(7):1350-64. Epub 2015 Apr 27 doi: 10.1016/j.ejrad.2015.04.011. PMID: 25958188
Antiestrogens--tamoxifen, SERMs and beyond.
Dhingra K
Invest New Drugs 1999;17(3):285-311. doi: 10.1023/a:1006348907994. PMID: 10665480

Diagnosis

Lipocalin-2: Structure, function, distribution and role in metabolic disorders.
Jaberi SA, Cohen A, D'Souza C, Abdulrazzaq YM, Ojha S, Bastaki S, Adeghate EA
Biomed Pharmacother 2021 Oct;142:112002. Epub 2021 Aug 27 doi: 10.1016/j.biopha.2021.112002. PMID: 34463264
"The unusual suspects"-Mammographic, sonographic, and histopathologic appearance of atypical breast masses.
Naeem M, Zulfiqar M, Ballard DH, Billadello L, Cao G, Winter A, Lowdermilk M
Clin Imaging 2020 Oct;66:111-120. Epub 2020 May 3 doi: 10.1016/j.clinimag.2020.04.039. PMID: 32470708Free PMC Article
Endocrine pathology: past, present and future.
Asa SL, Mete O
Pathology 2018 Jan;50(1):111-118. Epub 2017 Nov 11 doi: 10.1016/j.pathol.2017.09.003. PMID: 29132721
How to approach breast lesions in children and adolescents.
Gao Y, Saksena MA, Brachtel EF, terMeulen DC, Rafferty EA
Eur J Radiol 2015 Jul;84(7):1350-64. Epub 2015 Apr 27 doi: 10.1016/j.ejrad.2015.04.011. PMID: 25958188
MicroRNAs as biomarkers in pituitary tumors.
Di Ieva A, Butz H, Niamah M, Rotondo F, De Rosa S, Sav A, Yousef GM, Kovacs K, Cusimano MD
Neurosurgery 2014 Aug;75(2):181-9; discussion 188-9. doi: 10.1227/NEU.0000000000000369. PMID: 24739366

Therapy

Cost in the United States of FDA-approved small molecule protein kinase inhibitors used in the treatment of neoplastic and non-neoplastic diseases.
Roskoski R Jr
Pharmacol Res 2024 Jan;199:107036. Epub 2023 Dec 12 doi: 10.1016/j.phrs.2023.107036. PMID: 38096958
Mechanism-Based Sonodynamic-Chemo Combinations against Triple-Negative Breast Cancer.
Feng X, Wu C, Yang W, Wu J, Wang P
Int J Mol Sci 2022 Jul 20;23(14) doi: 10.3390/ijms23147981. PMID: 35887326Free PMC Article
Properties of FDA-approved small molecule protein kinase inhibitors: A 2020 update.
Roskoski R Jr
Pharmacol Res 2020 Feb;152:104609. Epub 2019 Dec 17 doi: 10.1016/j.phrs.2019.104609. PMID: 31862477
Achieving Reliable Diagnosis in Late Breast Implant Seromas: From Reactive to Anaplastic Large Cell Lymphoma.
Di Napoli A
Plast Reconstr Surg 2019 Mar;143(3S A Review of Breast Implant-Associated Anaplastic Large Cell Lymphoma):15S-22S. doi: 10.1097/PRS.0000000000005565. PMID: 30817552
Antiestrogens--tamoxifen, SERMs and beyond.
Dhingra K
Invest New Drugs 1999;17(3):285-311. doi: 10.1023/a:1006348907994. PMID: 10665480

Prognosis

Rosai-Dorfman disease of the breast: a clinicoradiologic and pathologic study.
Wang Q, Bradley K, Zhang M, Li S, Li X
Hum Pathol 2023 Nov;141:30-42. Epub 2023 Sep 9 doi: 10.1016/j.humpath.2023.08.009. PMID: 37673345
microRNA-140: A miRNA with diverse roles in human diseases.
Ghafouri-Fard S, Bahroudi Z, Shoorei H, Abak A, Ahin M, Taheri M
Biomed Pharmacother 2021 Mar;135:111256. Epub 2021 Feb 1 doi: 10.1016/j.biopha.2021.111256. PMID: 33434855
Endocrine pathology: past, present and future.
Asa SL, Mete O
Pathology 2018 Jan;50(1):111-118. Epub 2017 Nov 11 doi: 10.1016/j.pathol.2017.09.003. PMID: 29132721
MicroRNAs as biomarkers in pituitary tumors.
Di Ieva A, Butz H, Niamah M, Rotondo F, De Rosa S, Sav A, Yousef GM, Kovacs K, Cusimano MD
Neurosurgery 2014 Aug;75(2):181-9; discussion 188-9. doi: 10.1227/NEU.0000000000000369. PMID: 24739366
Mucins in the pathogenesis of breast cancer: implications in diagnosis, prognosis and therapy.
Mukhopadhyay P, Chakraborty S, Ponnusamy MP, Lakshmanan I, Jain M, Batra SK
Biochim Biophys Acta 2011 Apr;1815(2):224-40. Epub 2011 Jan 26 doi: 10.1016/j.bbcan.2011.01.001. PMID: 21277939Free PMC Article

Clinical prediction guides

microRNA-140: A miRNA with diverse roles in human diseases.
Ghafouri-Fard S, Bahroudi Z, Shoorei H, Abak A, Ahin M, Taheri M
Biomed Pharmacother 2021 Mar;135:111256. Epub 2021 Feb 1 doi: 10.1016/j.biopha.2021.111256. PMID: 33434855
Mediterranean Diet and Breast Cancer Risk.
Turati F, Carioli G, Bravi F, Ferraroni M, Serraino D, Montella M, Giacosa A, Toffolutti F, Negri E, Levi F, La Vecchia C
Nutrients 2018 Mar 8;10(3) doi: 10.3390/nu10030326. PMID: 29518016Free PMC Article
Endocrine pathology: past, present and future.
Asa SL, Mete O
Pathology 2018 Jan;50(1):111-118. Epub 2017 Nov 11 doi: 10.1016/j.pathol.2017.09.003. PMID: 29132721
MicroRNAs as biomarkers in pituitary tumors.
Di Ieva A, Butz H, Niamah M, Rotondo F, De Rosa S, Sav A, Yousef GM, Kovacs K, Cusimano MD
Neurosurgery 2014 Aug;75(2):181-9; discussion 188-9. doi: 10.1227/NEU.0000000000000369. PMID: 24739366
How many molecular subtypes? Implications of the unique tumor principle in personalized medicine.
Ogino S, Fuchs CS, Giovannucci E
Expert Rev Mol Diagn 2012 Jul;12(6):621-8. doi: 10.1586/erm.12.46. PMID: 22845482Free PMC Article

Recent systematic reviews

Ki-67 assessment of pancreatic neuroendocrine neoplasms: Systematic review and meta-analysis of manual vs. digital pathology scoring.
Luchini C, Pantanowitz L, Adsay V, Asa SL, Antonini P, Girolami I, Veronese N, Nottegar A, Cingarlini S, Landoni L, Brosens LA, Verschuur AV, Mattiolo P, Pea A, Mafficini A, Milella M, Niazi MK, Gurcan MN, Eccher A, Cree IA, Scarpa A
Mod Pathol 2022 Jun;35(6):712-720. Epub 2022 Mar 5 doi: 10.1038/s41379-022-01055-1. PMID: 35249100Free PMC Article

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