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Non-Neoplastic Retinal Disorder

MedGen UID:: 233241
•Concept ID:: C1335039
•: Disease or Syndrome

Definition

A non-neoplastic disorder that affects the retina. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVNon-Neoplastic Retinal Disorder

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Disorder by Site
      - Disorder of orbital region
        Non-Neoplastic Eye Disorder
        Non-Neoplastic Retinal Disorder
        Congenital hypertrophy of retinal pigment epithelium
        Grouped congenital hypertrophy of retinal pigment epithelium
        Multiple bilateral congenital hypertrophy of retinal pigment epithelium
        Solitary congenital hypertrophy of retinal pigment epithelium
        Macular edema
        Cystoid macular edema
        Macular hole
        Full-thickness macular hole
        Nodular and Massive Retinal Gliosis
        Preretinal fibrosis
        Reactive Hyperplasia of the Retinal Pigment Epithelium
        Retinal degeneration
        Macular degeneration
        Age-related macular degeneration
        Cystoid macular degeneration
        Foveal degeneration
        Geographic atrophy
        Stargardt disease
        Vitelliform macular dystrophy
        Wet macular degeneration
        Peripheral retinal degeneration
        Lattice retinal degeneration
        Peripheral cystoid retinal degeneration
        Retinal atrophy
        Macular atrophy
        Peripheral retinal atrophy
        Retinal pigment epithelial atrophy
        Retinal drusen
        Retinal dystrophy
        Chorioretinal dystrophy
        Cone-rod dystrophy
        Cone-rod dystrophy 21
        Genetic Macular Dystrophy
        Hereditary retinal dystrophy
        Pattern dystrophy of the retina
        Retinitis pigmentosa
        Rod-cone dystrophy
        Retinitis pigmentosa inversa
        Retinoschisis
        Foveoschisis
        Retinal Detachment and Defect
        Retinal Defect
        Retinal fold
        Retinal detachment
        Exudative retinal detachment
        Peripheral retinal detachment
        Retinal nonattachment
        Rhegmatogenous retinal detachment
        Tractional retinal detachment
        Retinal hamartoma
        Combined hamartoma of the retinal pigment epithelium and retina
        Retinal astrocytic hamartoma
        Retinal racemose hemangioma
        Simple Hamartoma of the Retinal Pigment Epithelium
        Retinal vascular disorder
        Diabetic retinopathy
        Background diabetic retinopathy
        Proliferative diabetic retinopathy
        Retinal vascular occlusion
        Retinal arterial occlusion
        Retinal vein occlusion
        Retinitis
        Acute retinal necrosis syndrome
        Chorioretinitis
        Birdshot chorioretinopathy
        Cytomegalovirus retinitis
        Retinopathy
        Angioid streaks
        Central serous chorioretinopathy
        Cone dystrophy
        Color vision deficiency
        Exudative retinopathy
        Exudative vitreoretinopathy 1
        Familial exudative vitreoretinopathy
        Hypertensive retinopathy
        Retinal arterial macroaneurysms
        Leber congenital amaurosis
        Leber congenital amaurosis 1
        Leber congenital amaurosis 2
        Leber congenital amaurosis 3
        Leber congenital amaurosis 4
        Leber congenital amaurosis 5
        Leber congenital amaurosis 6
        Leber congenital amaurosis 7
        Leber congenital amaurosis 8
        Leber congenital amaurosis 9
        Leber congenital amaurosis 10
        Leber congenital amaurosis 11
        Leber congenital amaurosis 12
        Leber congenital amaurosis 13
        Leber congenital amaurosis 14
        Leber congenital amaurosis 15
        Leber congenital amaurosis 16
        Proliferative retinopathy
        Bilateral Proliferative Retinopathy
        Proliferative vitreoretinopathy
        Radiation retinopathy
        Retina neoplasm
        Benign neoplasm of retina
        Malignant tumor of retina
        Retinal capillary hemangioma
        Retinal cell neoplasm
        Retinoblastoma
        Retinal dysplasia
        Retinal hemorrhage
        Intraretinal hemorrhage
        Sub-inner limiting membrane hemorrhage
        Subretinal hemorrhage
        Subretinal pigment epithelium hemorrhage
        Retinal neovascularization
        Peripheral retinal neovascularization
        Posterior retinal neovascularization
        Retinal perforation
        Retinal hole
        Retinal vasculitis
        Retinal arteritis
        Retinopathy of prematurity
        Retinopathy of prematurity plus
        Retinopathy of prematurity pre-plus
        Retinopathy of prematurity prethreshold
        Retinopathy of prematurity stage 1
        Retinopathy of prematurity stage 2
        Retinopathy of prematurity stage 3
        Retinopathy of prematurity stage 4
        Retinopathy of prematurity stage 5
        Retinopathy of prematurity threshold
        Retinopathy of Prematurity with Plus Disease
        Retinopathy of prematurity zone I
        Retinopathy of prematurity zone II
        Retinopathy of prematurity zone III

Professional guidelines

PubMed

SER recommendations for the treatment of uveitis.

Beltrán Catalán E, Brito García N, Pato Cour E, Muñoz Fernández S, Gómez Gómez A, Díaz Valle D, Hernández Garfella M, Francisco Hernández FM, Trujillo Martín MDM, Silva Fernández L, Villanueva G, Suárez Cuba J, Blanco R
Reumatol Clin (Engl Ed) 2023 Nov;19(9):465-477. Epub 2023 Oct 13 doi: 10.1016/j.reumae.2023.07.003. PMID: 37839964

See all (1)

Recent clinical studies

Etiology

Vitrectomy and tumor endoresection for the diagnosis and treatment of focal nodular retinal gliosis.

Ferreira CC, João D, Furtado A, Sousa-Neves F, Fonseca S, Sepúlveda P, Bilhoto M
Digit J Ophthalmol 2023;29(3):83-87. Epub 2023 Sep 30 doi: 10.5693/djo.02.2023.07.004. PMID: 37780040 Free PMC Article

Neurofibromatosis type 1-associated optic pathway gliomas: pathogenesis and emerging treatments.

Amato A, Imbimbo BP, Falsini B
Eur Rev Med Pharmacol Sci 2023 Jun;27(12):5636-5653. doi: 10.26355/eurrev_202306_32804. PMID: 37401302

A unique telomere DNA expansion phenotype in human retinal rod photoreceptors associated with aging and disease.

Bell WR, Meeker AK, Rizzo A, Rajpara S, Rosenthal IM, Flores Bellver M, Aparicio Domingo S, Zhong X, Barber JR, Joshu CE, Canto-Soler MV, Eberhart CG, Heaphy CM
Brain Pathol 2019 Jan;29(1):45-52. Epub 2018 May 23 doi: 10.1111/bpa.12618. PMID: 29668072 Free PMC Article

Cause-specific mortality in long-term survivors of retinoblastoma.

Yu CL, Tucker MA, Abramson DH, Furukawa K, Seddon JM, Stovall M, Fraumeni JF Jr, Kleinerman RA
J Natl Cancer Inst 2009 Apr 15;101(8):581-91. Epub 2009 Apr 7 doi: 10.1093/jnci/djp046. PMID: 19351917 Free PMC Article

Retinoblastoma: expression of HLA-G.

Adithi M, Kandalam M, Ramkumar HL, Subramanian A, Venkatesan N, Krishnakumar S
Ocul Immunol Inflamm 2006 Aug;14(4):207-13. doi: 10.1080/09273940600826497. PMID: 16911982

See all (14)

Diagnosis

Vitrectomy and tumor endoresection for the diagnosis and treatment of focal nodular retinal gliosis.

Neurofibromatosis type 1-associated optic pathway gliomas: pathogenesis and emerging treatments.

Amato A, Imbimbo BP, Falsini B
Eur Rev Med Pharmacol Sci 2023 Jun;27(12):5636-5653. doi: 10.26355/eurrev_202306_32804. PMID: 37401302

Therapeutic and toxicologic evaluation of anti-lipogenic agents in cancer cells compared with non-neoplastic cells.

Deepa PR, Vandhana S, Jayanthi U, Krishnakumar S
Basic Clin Pharmacol Toxicol 2012 Jun;110(6):494-503. Epub 2012 Jan 16 doi: 10.1111/j.1742-7843.2011.00844.x. PMID: 22151915

Cause-specific mortality in long-term survivors of retinoblastoma.

Tumors and pseudotumors of the optic disc.

Shields JA
Acta Ophthalmol Scand 2000 Apr;78(2):156-63. doi: 10.1034/j.1600-0420.2000.078002156.x. PMID: 10794248

See all (15)

Therapy

Vitrectomy and tumor endoresection for the diagnosis and treatment of focal nodular retinal gliosis.

Neurofibromatosis type 1-associated optic pathway gliomas: pathogenesis and emerging treatments.

Amato A, Imbimbo BP, Falsini B
Eur Rev Med Pharmacol Sci 2023 Jun;27(12):5636-5653. doi: 10.26355/eurrev_202306_32804. PMID: 37401302

Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review.

Plantone D, Koudriavtseva T
Clin Drug Investig 2018 Aug;38(8):653-671. doi: 10.1007/s40261-018-0656-y. PMID: 29737455

Radiation therapy: posterior segment complications.

Seregard S, Pelayes DE, Singh AD
Dev Ophthalmol 2013;52:114-23. Epub 2013 Aug 26 doi: 10.1159/000351088. PMID: 23989132

Proliferative vitreoretinopathy and chemotherapeutic agents.

Peyman GA, Schulman J
Surv Ophthalmol 1985 May-Jun;29(6):434-42. doi: 10.1016/0039-6257(85)90208-5. PMID: 3892742

See all (9)

Prognosis

Autoimmune retinopathies: a report of 3 cases.

Oray M, Kir N, Tuncer S, Onal S, Tugal-Tutkun I
Ocul Immunol Inflamm 2013 Dec;21(6):424-33. Epub 2013 Jun 3 doi: 10.3109/09273948.2013.799215. PMID: 23730997

Comparative proteomic analysis of differentially expressed proteins in primary retinoblastoma tumors.

Mallikarjuna K, Sundaram CS, Sharma Y, Deepa PR, Khetan V, Gopal L, Biswas J, Sharma T, Krishnakumar S
Proteomics Clin Appl 2010 Apr;4(4):449-63. Epub 2010 Jan 4 doi: 10.1002/prca.200900069. PMID: 21137063

Cause-specific mortality in long-term survivors of retinoblastoma.

Expression of high mobility group A2 protein in retinoblastoma and its association with clinicopathologic features.

Venkatesan N, Kandalam M, Pasricha G, Sumantran V, Manfioletti G, Ono SJ, Reddy MA, Krishnakumar S
J Pediatr Hematol Oncol 2009 Mar;31(3):209-14. doi: 10.1097/MPH.0b013e318197978d. PMID: 19262251

See all (4)

Clinical prediction guides

A unique telomere DNA expansion phenotype in human retinal rod photoreceptors associated with aging and disease.

Targeting HSP90/Survivin using a cell permeable structure based peptido-mimetic shepherdin in retinoblastoma.

Venkatesan N, Kanwar JR, Deepa PR, Navaneethakrishnan S, Joseph C, Krishnakumar S
Chem Biol Interact 2016 May 25;252:141-9. Epub 2016 Apr 7 doi: 10.1016/j.cbi.2016.04.011. PMID: 27062892

Comparative proteomic analysis of differentially expressed proteins in primary retinoblastoma tumors.

Tumor-associated retinal astrocytes promote retinoblastoma cell proliferation through production of IGFBP-5.

Xu XL, Lee TC, Offor N, Cheng C, Liu A, Fang Y, Jhanwar SC, Abramson DH, Cobrinik D
Am J Pathol 2010 Jul;177(1):424-35. Epub 2010 May 27 doi: 10.2353/ajpath.2010.090512. PMID: 20508032 Free PMC Article

Retinoblastoma: expression of HLA-G.

Adithi M, Kandalam M, Ramkumar HL, Subramanian A, Venkatesan N, Krishnakumar S
Ocul Immunol Inflamm 2006 Aug;14(4):207-13. doi: 10.1080/09273940600826497. PMID: 16911982

See all (7)

MedGen

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Non-Neoplastic Retinal Disorder

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Supplemental Content

Table of contents

Practice guidelines

Related information

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