U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Squamous cell breast carcinoma

MedGen UID:
233465
•Concept ID:
C1336079
•
Neoplastic Process
Synonyms: breast primary squamous cell carcinoma; Breast Squamous Cell Carcinoma; breast squamous cell carcinoma; metaplastic squamous cell carcinoma; Primary Squamous Cell Breast Carcinoma; primary squamous cell breast carcinoma; Primary Squamous Cell Carcinoma of Breast; primary squamous cell carcinoma of breast; Primary Squamous Cell Carcinoma of the Breast; primary squamous cell carcinoma of the breast; SCC of Breast; scc of breast; SCC of the Breast; scc of the breast; Squamous Breast Carcinoma; squamous breast carcinoma; Squamous Carcinoma of Breast; squamous carcinoma of breast; Squamous Carcinoma of the Breast; squamous carcinoma of the breast; Squamous Cell Breast Carcinoma; squamous cell breast carcinoma; Squamous Cell Carcinoma of Breast; squamous cell carcinoma of breast; Squamous Cell Carcinoma of the Breast; squamous cell carcinoma of the breast
 
Monarch Initiative: MONDO:0006056

Definition

A rare carcinoma that arises from the breast parenchyma and is entirely composed of squamous cells. [from NCI]

Professional guidelines

PubMed

Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation.
Mousset A, Lecorgne E, Bourget I, Lopez P, Jenovai K, Cherfils-Vicini J, Dominici C, Rios G, Girard-Riboulleau C, Liu B, Spector DL, Ehmsen S, Renault S, Hego C, Mechta-Grigoriou F, Bidard FC, Terp MG, Egeblad M, Gaggioli C, Albrengues J
Cancer Cell 2023 Apr 10;41(4):757-775.e10. doi: 10.1016/j.ccell.2023.03.008. PMID: 37037615Free PMC Article
Mechanisms, Diagnosis and Treatment of Bone Metastases.
Ban J, Fock V, Aryee DNT, Kovar H
Cells 2021 Oct 29;10(11) doi: 10.3390/cells10112944. PMID: 34831167Free PMC Article
A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer.
Bassez A, Vos H, Van Dyck L, Floris G, Arijs I, Desmedt C, Boeckx B, Vanden Bempt M, Nevelsteen I, Lambein K, Punie K, Neven P, Garg AD, Wildiers H, Qian J, Smeets A, Lambrechts D
Nat Med 2021 May;27(5):820-832. Epub 2021 May 6 doi: 10.1038/s41591-021-01323-8. PMID: 33958794

Recent clinical studies

Diagnosis

Neoadjuvant therapy for HER2-positive acantholytic squamous cell breast carcinoma: a case report.
Cong J, Jo H, Zou N, Kong L, Ri H
J Int Med Res 2023 Aug;51(8):3000605231187936. doi: 10.1177/03000605231187936. PMID: 37534455Free PMC Article
Breast abscess as the initial manifestation of primary pure squamous cell carcinoma: a rare presentation and literature review.
Salemis NS
Breast Dis 2011;33(3):125-31. doi: 10.3233/BD-2012-0335. PMID: 22571936
A case of HER-2(+) squamous cell breast carcinoma: an unusual presentation of an unusual clinical entity.
Karamouzis MV, Fida A, Apostolikas N, Rigatos G
Eur J Surg Oncol 2006 Dec;32(10):1250-1. Epub 2006 Jun 21 doi: 10.1016/j.ejso.2006.05.008. PMID: 16797157
Squamous cell carcinoma of the breast diagnosis by vacuum-assisted core biopsy.
Guerriero G, Zagami MG, Montesano M, Primavera A, Carino R, Battista C, Rabitti C, Altomare V
Tumori 2005 Sep-Oct;91(5):418-20. doi: 10.1177/030089160509100507. PMID: 16459639
A pure primary squamous cell breast carcinoma presenting as a breast abscess: case report and review of literature.
Cappellani A, Di Vita M, Zanghì A, De Luca A, Tomarchio G, La Porta D, Lanzafame S, Alfano G
Ann Ital Chir 2004 Mar-Apr;75(2):259-62; discussion 262-3. PMID: 15387000

Therapy

Neoadjuvant therapy for HER2-positive acantholytic squamous cell breast carcinoma: a case report.
Cong J, Jo H, Zou N, Kong L, Ri H
J Int Med Res 2023 Aug;51(8):3000605231187936. doi: 10.1177/03000605231187936. PMID: 37534455Free PMC Article

Prognosis

Breast abscess as the initial manifestation of primary pure squamous cell carcinoma: a rare presentation and literature review.
Salemis NS
Breast Dis 2011;33(3):125-31. doi: 10.3233/BD-2012-0335. PMID: 22571936

Clinical prediction guides

A pure primary squamous cell breast carcinoma presenting as a breast abscess: case report and review of literature.
Cappellani A, Di Vita M, Zanghì A, De Luca A, Tomarchio G, La Porta D, Lanzafame S, Alfano G
Ann Ital Chir 2004 Mar-Apr;75(2):259-62; discussion 262-3. PMID: 15387000

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...