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Intermediate cell type ciliary body melanoma

MedGen UID:
233563
•Concept ID:
C1334209
•
Neoplastic Process
Synonyms: Ciliary Body Intermediate Cell Type Melanoma; ciliary body intermediate cell type uveal melanoma; Intermediate Cell Type Ciliary Body Melanoma; intermediate cell type ciliary body melanoma; intermediate cell type uveal melanoma of ciliary body
 
Monarch Initiative: MONDO:0004066

Definition

Ciliary body melanoma characterized by the presence of intermediate cells which are similar to but smaller than epithelioid cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntermediate cell type ciliary body melanoma

Recent clinical studies

Etiology

Adding the Cancer Genome Atlas Chromosome Classes to American Joint Committee on Cancer System Offers More Precise Prognostication in Uveal Melanoma.
Gelmi MC, Bas Z, Malkani K, Ganguly A, Shields CL, Jager MJ
Ophthalmology 2022 Apr;129(4):431-437. Epub 2021 Nov 16 doi: 10.1016/j.ophtha.2021.11.018. PMID: 34793831

Diagnosis

Microcirculation and tumor-infiltrating macrophages in choroidal and ciliary body melanoma and corresponding metastases.
Toivonen P, Mäkitie T, Kujala E, Kivelä T
Invest Ophthalmol Vis Sci 2004 Jan;45(1):1-6. doi: 10.1167/iovs.03-0622. PMID: 14691146
Choroidal schwannoma: immunohistochemical and electron-microscopic study.
Matsuo T, Notohara K
Ophthalmologica 2000;214(2):156-60. doi: 10.1159/000027488. PMID: 10720924

Prognosis

Adding the Cancer Genome Atlas Chromosome Classes to American Joint Committee on Cancer System Offers More Precise Prognostication in Uveal Melanoma.
Gelmi MC, Bas Z, Malkani K, Ganguly A, Shields CL, Jager MJ
Ophthalmology 2022 Apr;129(4):431-437. Epub 2021 Nov 16 doi: 10.1016/j.ophtha.2021.11.018. PMID: 34793831
Microcirculation and tumor-infiltrating macrophages in choroidal and ciliary body melanoma and corresponding metastases.
Toivonen P, Mäkitie T, Kujala E, Kivelä T
Invest Ophthalmol Vis Sci 2004 Jan;45(1):1-6. doi: 10.1167/iovs.03-0622. PMID: 14691146
Biologic determinants of uveal melanoma metastatic phenotype: role of intermediate filaments as predictive markers.
Hendrix MJ, Seftor EA, Seftor RE, Gardner LM, Boldt HC, Meyer M, Pe'er J, Folberg R
Lab Invest 1998 Feb;78(2):153-63. PMID: 9484713

Clinical prediction guides

Adding the Cancer Genome Atlas Chromosome Classes to American Joint Committee on Cancer System Offers More Precise Prognostication in Uveal Melanoma.
Gelmi MC, Bas Z, Malkani K, Ganguly A, Shields CL, Jager MJ
Ophthalmology 2022 Apr;129(4):431-437. Epub 2021 Nov 16 doi: 10.1016/j.ophtha.2021.11.018. PMID: 34793831
Microcirculation and tumor-infiltrating macrophages in choroidal and ciliary body melanoma and corresponding metastases.
Toivonen P, Mäkitie T, Kujala E, Kivelä T
Invest Ophthalmol Vis Sci 2004 Jan;45(1):1-6. doi: 10.1167/iovs.03-0622. PMID: 14691146
Structure, development and function of cytoskeletal elements in non-neuronal cells of the human eye.
Kivelä T, Uusitalo M
Prog Retin Eye Res 1998 Jul;17(3):385-428. doi: 10.1016/s1350-9462(98)00001-9. PMID: 9695798
Biologic determinants of uveal melanoma metastatic phenotype: role of intermediate filaments as predictive markers.
Hendrix MJ, Seftor EA, Seftor RE, Gardner LM, Boldt HC, Meyer M, Pe'er J, Folberg R
Lab Invest 1998 Feb;78(2):153-63. PMID: 9484713

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