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Eccrine sweat gland cancer

MedGen UID:
233660
•Concept ID:
C1334577
•
Neoplastic Process
Synonyms: cancer of eccrine sweat gland; eccrine sweat gland cancer; Malignant Eccrine Neoplasm; malignant eccrine neoplasm; Malignant Eccrine Neoplasm of Skin; malignant eccrine neoplasm of skin; Malignant Eccrine Neoplasm of the Skin; malignant eccrine neoplasm of the skin; Malignant Eccrine Skin Neoplasm; malignant eccrine skin neoplasm; Malignant Eccrine Skin Tumor; malignant eccrine skin tumor; malignant eccrine skin tumour; malignant eccrine sweat gland neoplasm; Malignant Eccrine Tumor; malignant eccrine tumor; Malignant Eccrine Tumor of Skin; malignant eccrine tumor of skin; Malignant Eccrine Tumor of the Skin; malignant eccrine tumor of the skin; malignant eccrine tumour; malignant eccrine tumour of skin; malignant eccrine tumour of the skin; malignant neoplasm of eccrine sweat gland
 
Monarch Initiative: MONDO:0005506

Definition

A malignant neoplasm involving the eccrine glands. [from NCI]

Professional guidelines

PubMed

Current Diagnosis and Treatment Options for Cutaneous Adnexal Neoplasms with Apocrine and Eccrine Differentiation.
Płachta I, Kleibert M, Czarnecka AM, Spałek M, Szumera-Ciećkiewicz A, Rutkowski P
Int J Mol Sci 2021 May 11;22(10) doi: 10.3390/ijms22105077. PMID: 34064849Free PMC Article
Challenges in diagnosis and management of a spiradenocarcinoma: a comprehensive literature review.
Wagner K, Jassal K, Lee JC, Ban EJ, Cameron R, Serpell J
ANZ J Surg 2021 Oct;91(10):1996-2001. Epub 2021 Feb 1 doi: 10.1111/ans.16626. PMID: 33522696
Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends.
Kallini JR, Hamed N, Khachemoune A
Int J Dermatol 2015 Feb;54(2):130-40. Epub 2014 Nov 27 doi: 10.1111/ijd.12553. PMID: 25428226

Recent clinical studies

Etiology

SARS-CoV-2 and Skin: New Insights and Perspectives.
Cazzato G, Cascardi E, Colagrande A, Foti C, Stellacci A, Marrone M, Ingravallo G, Arezzo F, Loizzi V, Solimando AG, Parente P, Maiorano E, Cormio G, Vacca A, Resta L
Biomolecules 2022 Aug 31;12(9) doi: 10.3390/biom12091212. PMID: 36139051Free PMC Article
Porocarcinoma: a review.
Joshy J, Mistry K, Levell NJ, van Bodegraven B, Vernon S, Rajan N, Craig P, Venables ZC
Clin Exp Dermatol 2022 Jun;47(6):1030-1035. Epub 2022 Mar 20 doi: 10.1111/ced.15126. PMID: 35149987
Squamoid Eccrine Ductal Carcinoma.
Svoboda SA, Rush PS, Garofola CJ, Grider DJ, Prickett KA, Phillips MA
Cutis 2021 Jun;107(6):E5-E9. doi: 10.12788/cutis.0280. PMID: 34314321
Alternative Clinical Indications of Botulinum Toxin.
Alster TS, Harrison IS
Am J Clin Dermatol 2020 Dec;21(6):855-880. doi: 10.1007/s40257-020-00532-0. PMID: 32651806
Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends.
Kallini JR, Hamed N, Khachemoune A
Int J Dermatol 2015 Feb;54(2):130-40. Epub 2014 Nov 27 doi: 10.1111/ijd.12553. PMID: 25428226

Diagnosis

Adnexal and Sebaceous Carcinomas.
Seger EW, Neill BC, Tolkachjov SN
Dermatol Clin 2023 Jan;41(1):117-132. Epub 2022 Oct 28 doi: 10.1016/j.det.2022.07.010. PMID: 36410972
Squamoid Eccrine Ductal Carcinoma.
Svoboda SA, Rush PS, Garofola CJ, Grider DJ, Prickett KA, Phillips MA
Cutis 2021 Jun;107(6):E5-E9. doi: 10.12788/cutis.0280. PMID: 34314321
Apocrine and eccrine hidrocystomas: a clinicopathological study.
Koumaki D, Papadakis M, Lagoudaki E, Manios GA, Kassotakis D, Doxastaki A, Krasagakis K, Manios A
Acta Dermatovenerol Alp Pannonica Adriat 2021 Jun;30(2):53-56. PMID: 34169699
Coccygeal Polypoid Eccrine Nevus.
Charifa A, Ko CJ
Arch Pathol Lab Med 2019 Jul;143(7):890-892. Epub 2018 Dec 28 doi: 10.5858/arpa.2018-0055-RS. PMID: 30605023
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149

Therapy

Alternative Clinical Indications of Botulinum Toxin.
Alster TS, Harrison IS
Am J Clin Dermatol 2020 Dec;21(6):855-880. doi: 10.1007/s40257-020-00532-0. PMID: 32651806
Post-brachytherapy wound.
Gardner S
Br J Nurs 2017 Nov 8;26(Sup20a):S16-S17. doi: 10.12968/bjon.2017.26.Sup20a.S16. PMID: 29144783
Chemotherapy of rare skin adnexal tumors: a review of literature.
De Iuliis F, Amoroso L, Taglieri L, Vendittozzi S, Blasi L, Salerno G, Lanza R, Scarpa S
Anticancer Res 2014 Oct;34(10):5263-8. PMID: 25275018
Angioadnexocentric nevus.
Hashimoto K, Amano M, Setoyama M
J Dermatol 2012 Nov;39(11):909-15. Epub 2012 Jul 4 doi: 10.1111/j.1346-8138.2012.01599.x. PMID: 22762690
Eccrine porocarcinoma.
Brown CW Jr, Dy LC
Dermatol Ther 2008 Nov-Dec;21(6):433-8. doi: 10.1111/j.1529-8019.2008.00243.x. PMID: 19076620

Prognosis

Adnexal and Sebaceous Carcinomas.
Seger EW, Neill BC, Tolkachjov SN
Dermatol Clin 2023 Jan;41(1):117-132. Epub 2022 Oct 28 doi: 10.1016/j.det.2022.07.010. PMID: 36410972
Porocarcinoma: a review.
Joshy J, Mistry K, Levell NJ, van Bodegraven B, Vernon S, Rajan N, Craig P, Venables ZC
Clin Exp Dermatol 2022 Jun;47(6):1030-1035. Epub 2022 Mar 20 doi: 10.1111/ced.15126. PMID: 35149987
Sweat Gland Tumor Microenvironment.
Yuda Handaya A, Anwar SL, Fauzi AR, Werdana VAP
Adv Exp Med Biol 2020;1296:259-274. doi: 10.1007/978-3-030-59038-3_16. PMID: 34185298
Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends.
Kallini JR, Hamed N, Khachemoune A
Int J Dermatol 2015 Feb;54(2):130-40. Epub 2014 Nov 27 doi: 10.1111/ijd.12553. PMID: 25428226
Malignant adnexal neoplasms.
Crowson AN, Magro CM, Mihm MC
Mod Pathol 2006 Feb;19 Suppl 2:S93-S126. doi: 10.1038/modpathol.3800511. PMID: 16446719

Clinical prediction guides

NECTIN4 expression in sebaceous and sweat gland carcinoma.
Ito T, Hashimoto H, Tanaka Y, Tanegashima K, Murata M, Oda Y, Kaku-Ito Y
Eur J Dermatol 2022 Apr 1;32(2):181-186. doi: 10.1684/ejd.2022.4241. PMID: 35866909
Apocrine and eccrine hidrocystomas: a clinicopathological study.
Koumaki D, Papadakis M, Lagoudaki E, Manios GA, Kassotakis D, Doxastaki A, Krasagakis K, Manios A
Acta Dermatovenerol Alp Pannonica Adriat 2021 Jun;30(2):53-56. PMID: 34169699
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149
Syringometaplasia: variants and underlying mechanisms.
Abbas O, Bhawan J
Int J Dermatol 2016 Feb;55(2):142-8. Epub 2015 Oct 13 doi: 10.1111/ijd.13040. PMID: 26460811
Eccrine porocarcinoma.
Akiyoshi E, Nogita T, Yamaguchi R, Toyoda H, Kawashima M, Hidano A
Dermatologica 1991;182(4):239-42. doi: 10.1159/000247804. PMID: 1653154

Recent systematic reviews

Dermoscopy of cutaneous adnexal tumours: a systematic review of the literature.
Lai M, Muscianese M, Piana S, Chester J, Borsari S, Paolino G, Pellacani G, Longo C, Pampena R
J Eur Acad Dermatol Venereol 2022 Sep;36(9):1524-1540. Epub 2022 May 25 doi: 10.1111/jdv.18210. PMID: 35536546Free PMC Article
The role of postoperative radiotherapy in eccrine porocarcinoma: a multidisciplinary systematic review.
Fionda B, Di Stefani A, Lancellotta V, Gentileschi S, Caretto AA, Casà C, Federico F, Rembielak A, Rossi E, Morganti AG, Schinzari G, Peris K, Tagliaferri L
Eur Rev Med Pharmacol Sci 2022 Mar;26(5):1695-1700. doi: 10.26355/eurrev_202203_28238. PMID: 35302218
A systematic review of periungual eccrine neoplasms.
Rao EM, Knackstedt TJ
Int J Dermatol 2022 Jul;61(7):812-820. Epub 2021 Sep 8 doi: 10.1111/ijd.15893. PMID: 34494261
Eccrine Porocarcinoma: New Insights and a Systematic Review of the Literature.
Nazemi A, Higgins S, Swift R, In G, Miller K, Wysong A
Dermatol Surg 2018 Oct;44(10):1247-1261. doi: 10.1097/DSS.0000000000001566. PMID: 29894433
Reference values for skin microanatomy: A systematic review and meta-analysis of ex vivo studies.
Xu H, Fonseca M, Wolner Z, Chung E, Wu X, Geller S, Dusza SW, DeRosa AP, Marghoob AA, Busam KJ, Halpern AC, Marchetti MA
J Am Acad Dermatol 2017 Dec;77(6):1133-1144.e4. Epub 2017 Jul 14 doi: 10.1016/j.jaad.2017.06.009. PMID: 28716435Free PMC Article

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