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Mediastinal schwannoma

MedGen UID:
233688
•Concept ID:
C1334679
•
Neoplastic Process
Synonyms: Benign Mediastinal Neurilemmoma; benign mediastinal neurilemmoma; Benign Mediastinal Schwannoma; benign mediastinal schwannoma; Benign Neurilemmoma of Mediastinum; benign neurilemmoma of mediastinum; Benign Neurilemmoma of the Mediastinum; benign neurilemmoma of the mediastinum; Benign Schwannoma of Mediastinum; benign schwannoma of mediastinum; Benign Schwannoma of the Mediastinum; benign schwannoma of the mediastinum; Mediastinal Neurilemmoma; mediastinal neurilemmoma; Mediastinal Schwannoma; mediastinal schwannoma; mediastinum schwannoma; Neurilemmoma of Mediastinum; neurilemmoma of mediastinum; Neurilemmoma of the Mediastinum; neurilemmoma of the mediastinum; Schwannoma of Mediastinum; schwannoma of mediastinum; Schwannoma of the Mediastinum; schwannoma of the mediastinum
 
Monarch Initiative: MONDO:0004398

Definition

A schwannoma that arises from the posterior mediastinum. It is the most common neurogenic tumor of the mediastinum. Excision is usually curative. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMediastinal schwannoma

Professional guidelines

PubMed

Surgical treatment of neurogenic tumors of the chest.
Yamaguchi M, Yoshino I, Fukuyama S, Osoegawa A, Kameyama T, Tagawa T, Maehara Y
Ann Thorac Cardiovasc Surg 2004 Jun;10(3):148-51. PMID: 15312009
Diagnostic imaging and surgical treatment of dumbbell tumors of the mediastinum.
Ricci C, Rendina EA, Venuta F, Pescarmona EO, Gagliardi F
Ann Thorac Surg 1990 Oct;50(4):586-9. doi: 10.1016/0003-4975(90)90194-b. PMID: 2222047

Recent clinical studies

Etiology

Intraoperative neuromonitoring in thoracoscopic excision of brachial plexus schwannoma.
Femia F, Junemann C, Ruffini E, Guerrera F
Interact Cardiovasc Thorac Surg 2022 Jan 6;34(1):156-158. Epub 2021 Aug 18 doi: 10.1093/icvts/ivab206. PMID: 34999804Free PMC Article
Successful excision of a giant mediastinal vagal schwannoma causing severe tracheal stenosis through a median sternotomy.
Ishibashi H, Takahashi K, Kumazawa S, Okubo K
Ann Thorac Surg 2014 Jul;98(1):336-8. doi: 10.1016/j.athoracsur.2013.09.028. PMID: 24996720
Cervico-mediastinal schwannoma of the vagus nerve: resection with intraoperative nerve monitoring.
Imperatori A, Dionigi G, De Monte L, Conti V, Rotolo N
Updates Surg 2011 Mar;63(1):59-61. Epub 2011 Jan 6 doi: 10.1007/s13304-010-0040-9. PMID: 21210273

Diagnosis

Huge mediastinal ancient schwannoma causing acute respiratory failure: a case report.
Huang HY, Lo CM, Lu HI, Chang JP
J Cardiothorac Surg 2024 Mar 15;19(1):131. doi: 10.1186/s13019-024-02605-1. PMID: 38491470Free PMC Article
Resection of a schwannoma originating from vagus nerve in the right superior mediastinum.
Zhang M, Shi H, Tu X, Li W, Wei Z
J Cardiothorac Surg 2023 Feb 10;18(1):69. doi: 10.1186/s13019-023-02177-6. PMID: 36759886Free PMC Article
Endobronchial ultrasound-guided transbronchial needle aspiration as a diagnostic modality for schwannoma: A case report.
Liu W, Li Y, Chen L, Liu Z, Zhang W
Medicine (Baltimore) 2022 Jul 22;101(29):e29669. doi: 10.1097/MD.0000000000029669. PMID: 35866820Free PMC Article
Primary mediastinal melanotic schwannian tumors: A clinicopathological and immunohistochemical study of 5 cases.
Lindholm K, Moran CA
Ann Diagn Pathol 2018 Dec;37:103-106. Epub 2018 Oct 3 doi: 10.1016/j.anndiagpath.2018.10.001. PMID: 30316045
Posterior mediastinal schwannoma.
Fierro N, D'ermo G, Di Cola G, Gallinaro LS, Galassi G, Galassi G
Asian Cardiovasc Thorac Ann 2003 Mar;11(1):72-3. doi: 10.1177/021849230301100118. PMID: 12692029

Therapy

Acute shingles after resection of thoracic schwannoma.
Muesse JL, Blackmon SH, Harris RL, Kim MP
Tex Heart Inst J 2012;39(2):265-7. PMID: 22740749Free PMC Article
Thoracoscopic removal of middle mediastinal schwannoma originating from recurrent nerve.
Sasaki K, Kohno T, Mun M, Yoshiya T
Thorac Cardiovasc Surg 2008 Sep;56(6):375-7. doi: 10.1055/s-2008-1038471. PMID: 18704866

Prognosis

Huge mediastinal ancient schwannoma causing acute respiratory failure: a case report.
Huang HY, Lo CM, Lu HI, Chang JP
J Cardiothorac Surg 2024 Mar 15;19(1):131. doi: 10.1186/s13019-024-02605-1. PMID: 38491470Free PMC Article
Giant mediastinal schwannoma located in the lower right side of the chest.
Wu Y, Zhang J, Chai Y
Niger J Clin Pract 2016 Sep-Oct;19(5):678-80. doi: 10.4103/1119-3077.188701. PMID: 27538560
Massive hemoptysis: a rare presentation of posterior mediastinal, giant, benign vagal schwannoma.
Das A, Choudhury S, Basuthakur S, Mukhopadhyay A, Mukherjee S
Arch Iran Med 2014 Nov;17(11):779-82. PMID: 25365621
Successful excision of a giant mediastinal vagal schwannoma causing severe tracheal stenosis through a median sternotomy.
Ishibashi H, Takahashi K, Kumazawa S, Okubo K
Ann Thorac Surg 2014 Jul;98(1):336-8. doi: 10.1016/j.athoracsur.2013.09.028. PMID: 24996720
Mediastinal schwannoma diagnosed preoperatively as a cyst.
Taguchi S, Mori A, Suzuki R, Hasegawa I, Sato H, Sugiura H, Irie R
Tex Heart Inst J 2014 Feb;41(1):76-9. doi: 10.14503/THIJ-12-2760. PMID: 24512408Free PMC Article

Clinical prediction guides

Middle mediastinal schwannoma concealed by asthma and GORD.
Dy P, Lajom C, Sanchez J
BMJ Case Rep 2018 Mar 13;2018 doi: 10.1136/bcr-2017-223795. PMID: 29535096Free PMC Article
Mediastinal schwannoma diagnosed preoperatively as a cyst.
Taguchi S, Mori A, Suzuki R, Hasegawa I, Sato H, Sugiura H, Irie R
Tex Heart Inst J 2014 Feb;41(1):76-9. doi: 10.14503/THIJ-12-2760. PMID: 24512408Free PMC Article

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