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Metachronous kidney Wilms tumor

MedGen UID:
233696
•Concept ID:
C1334705
•
Neoplastic Process
Synonym: Metachronous kidney Wilms' tumor
 
Monarch Initiative: MONDO:0003317

Definition

Wilms tumor arising in the remaining kidney following treatment of the original Wilms tumor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetachronous kidney Wilms tumor

Professional guidelines

PubMed

Management of bilateral Wilms tumours.
Millar AJW, Cox S, Davidson A
Pediatr Surg Int 2017 Jul;33(7):737-745. Epub 2017 May 17 doi: 10.1007/s00383-017-4091-6. PMID: 28516188
Management of bilateral Wilms tumours.
Millar AJ, Cox S, Davidson A
Pediatr Surg Int 2017 Apr;33(4):461-469. Epub 2017 Jan 4 doi: 10.1007/s00383-016-4047-2. PMID: 28054101
Is partial nephrectomy appropriate treatment for unilateral Wilms' tumor?
Moorman-Voestermans CG, Aronson DC, Staalman CR, Delemarre JF, de Kraker J
J Pediatr Surg 1998 Feb;33(2):165-70. doi: 10.1016/s0022-3468(98)90425-0. PMID: 9498380

Recent clinical studies

Etiology

Clinical characteristics and outcomes of children with WAGR syndrome and Wilms tumor and/or nephroblastomatosis: The 30-year SIOP-RTSG experience.
Hol JA, Jongmans MCJ, Sudour-Bonnange H, Ramírez-Villar GL, Chowdhury T, Rechnitzer C, Pal N, Schleiermacher G, Karow A, Kuiper RP, de Camargo B, Avcin S, Redzic D, Wachtel A, Segers H, Vujanic GM, van Tinteren H, Bergeron C, Pritchard-Jones K, Graf N, van den Heuvel-Eibrink MM; International Society of Pediatric Oncology Renal Tumor Study Group (SIOP-RTSG)
Cancer 2021 Feb 15;127(4):628-638. Epub 2020 Nov 4 doi: 10.1002/cncr.33304. PMID: 33146894Free PMC Article
Neonatal renal tumours.
Powis M
Early Hum Dev 2010 Oct;86(10):607-12. doi: 10.1016/j.earlhumdev.2010.08.018. PMID: 20888153
Metachronous bilateral Wilms' tumor: the importance of time interval to the development of a second tumor.
Paulino AC, Thakkar B, Henderson WG
Cancer 1998 Jan 15;82(2):415-20. PMID: 9445201
Bilateral Wilms' tumor: long-term survival and some epidemiological features.
Coppes MJ, de Kraker J, van Dijken PJ, Perry HJ, Delemarre JF, Tournade MF, Lemerle J, Voûte PA
J Clin Oncol 1989 Mar;7(3):310-5. doi: 10.1200/JCO.1989.7.3.310. PMID: 2537383
Metachronous bilateral Wilms' tumor, National Wilms' Tumor Study.
Jones B, Hrabovsky E, Kiviat N, Breslow N
Am J Clin Oncol 1982 Oct;5(5):545-50. PMID: 6295133

Diagnosis

Clinical characteristics and outcomes of children with WAGR syndrome and Wilms tumor and/or nephroblastomatosis: The 30-year SIOP-RTSG experience.
Hol JA, Jongmans MCJ, Sudour-Bonnange H, Ramírez-Villar GL, Chowdhury T, Rechnitzer C, Pal N, Schleiermacher G, Karow A, Kuiper RP, de Camargo B, Avcin S, Redzic D, Wachtel A, Segers H, Vujanic GM, van Tinteren H, Bergeron C, Pritchard-Jones K, Graf N, van den Heuvel-Eibrink MM; International Society of Pediatric Oncology Renal Tumor Study Group (SIOP-RTSG)
Cancer 2021 Feb 15;127(4):628-638. Epub 2020 Nov 4 doi: 10.1002/cncr.33304. PMID: 33146894Free PMC Article
Management of bilateral Wilms tumours.
Millar AJW, Cox S, Davidson A
Pediatr Surg Int 2017 Jul;33(7):737-745. Epub 2017 May 17 doi: 10.1007/s00383-017-4091-6. PMID: 28516188
Neonatal renal tumours.
Powis M
Early Hum Dev 2010 Oct;86(10):607-12. doi: 10.1016/j.earlhumdev.2010.08.018. PMID: 20888153
Bilateral Wilms' tumor.
Kullendorff CM, Wiebe T
Pediatr Surg Int 1999;15(1):46-9. doi: 10.1007/s003830050510. PMID: 9914355
Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms' tumor.
Beckwith JB, Kiviat NB, Bonadio JF
Pediatr Pathol 1990;10(1-2):1-36. doi: 10.3109/15513819009067094. PMID: 2156243

Therapy

Management of bilateral Wilms tumours.
Millar AJ, Cox S, Davidson A
Pediatr Surg Int 2017 Apr;33(4):461-469. Epub 2017 Jan 4 doi: 10.1007/s00383-016-4047-2. PMID: 28054101
Bilateral Wilms' tumors: single-center experience with 22 cases and literature review.
Sarhan OM, El-Baz M, Sarhan MM, Ghali AM, Ghoneim MA
Urology 2010 Oct;76(4):946-51. Epub 2010 Aug 13 doi: 10.1016/j.urology.2010.03.055. PMID: 20708784
Bilateral Wilms' tumor.
Kullendorff CM, Wiebe T
Pediatr Surg Int 1999;15(1):46-9. doi: 10.1007/s003830050510. PMID: 9914355
Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms' tumor.
Beckwith JB, Kiviat NB, Bonadio JF
Pediatr Pathol 1990;10(1-2):1-36. doi: 10.3109/15513819009067094. PMID: 2156243
Metachronous bilateral Wilms' tumor, National Wilms' Tumor Study.
Jones B, Hrabovsky E, Kiviat N, Breslow N
Am J Clin Oncol 1982 Oct;5(5):545-50. PMID: 6295133

Prognosis

Synchronous bilateral Wilms' tumor with liver metastasis.
Sereke SG, Sahal AO, Mboizi V, Bongomin F
BMC Urol 2021 Jun 10;21(1):91. doi: 10.1186/s12894-021-00859-8. PMID: 34112148Free PMC Article
Management of bilateral Wilms tumours.
Millar AJW, Cox S, Davidson A
Pediatr Surg Int 2017 Jul;33(7):737-745. Epub 2017 May 17 doi: 10.1007/s00383-017-4091-6. PMID: 28516188
Management of bilateral Wilms tumours.
Millar AJ, Cox S, Davidson A
Pediatr Surg Int 2017 Apr;33(4):461-469. Epub 2017 Jan 4 doi: 10.1007/s00383-016-4047-2. PMID: 28054101
Metachronous bilateral Wilms' tumor: the importance of time interval to the development of a second tumor.
Paulino AC, Thakkar B, Henderson WG
Cancer 1998 Jan 15;82(2):415-20. PMID: 9445201
Metachronous bilateral Wilms' tumor, National Wilms' Tumor Study.
Jones B, Hrabovsky E, Kiviat N, Breslow N
Am J Clin Oncol 1982 Oct;5(5):545-50. PMID: 6295133

Clinical prediction guides

Wilms Tumor Associated With the 9q22.3 Microdeletion Syndrome: 2 New Case Reports and a Review of The Literature.
Cayrol J, Nightingale M, Challis J, Campbell M, Sullivan M, Heloury Y
J Pediatr Hematol Oncol 2019 Nov;41(8):e517-e520. doi: 10.1097/MPH.0000000000001322. PMID: 30371535
Clinical Outcome and Biological Predictors of Relapse After Nephrectomy Only for Very Low-risk Wilms Tumor: A Report From Children's Oncology Group AREN0532.
Fernandez CV, Perlman EJ, Mullen EA, Chi YY, Hamilton TE, Gow KW, Ferrer FA, Barnhart DC, Ehrlich PF, Khanna G, Kalapurakal JA, Bocking T, Huff V, Tian J, Geller JI, Grundy PE, Anderson JR, Dome JS, Shamberger RC
Ann Surg 2017 Apr;265(4):835-840. doi: 10.1097/SLA.0000000000001716. PMID: 27811504Free PMC Article
Experience with retroperitoneal partial nephrectomy in bilateral Wilms tumor.
Lim II, Honeyman JN, Fialkowski EA, Murphy JM, Price AP, Abramson SJ, Quaglia MP, Heaton TE
Eur J Pediatr Surg 2015 Feb;25(1):113-7. Epub 2014 Sep 2 doi: 10.1055/s-0034-1387944. PMID: 25181295Free PMC Article
Clinical relevance of mutations in the Wilms tumor suppressor 1 gene WT1 and the cadherin-associated protein beta1 gene CTNNB1 for patients with Wilms tumors: results of long-term surveillance of 71 patients from International Society of Pediatric Oncology Study 9/Society for Pediatric Oncology.
Royer-Pokora B, Weirich A, Schumacher V, Uschkereit C, Beier M, Leuschner I, Graf N, Autschbach F, Schneider D, von Harrach M
Cancer 2008 Sep 1;113(5):1080-9. doi: 10.1002/cncr.23672. PMID: 18618575
Is partial nephrectomy appropriate treatment for unilateral Wilms' tumor?
Moorman-Voestermans CG, Aronson DC, Staalman CR, Delemarre JF, de Kraker J
J Pediatr Surg 1998 Feb;33(2):165-70. doi: 10.1016/s0022-3468(98)90425-0. PMID: 9498380

Recent systematic reviews

The role of liver resection in metastatic nephroblastoma: a systematic review and Meta-regression analysis.
Fuchs J, Murtha-Lemekhova A, Kessler M, Günther P, Hoffmann K
BMC Cancer 2022 Jan 18;22(1):76. doi: 10.1186/s12885-022-09182-3. PMID: 35038991Free PMC Article

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