U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ovarian Leydig Cell Tumor, Not Otherwise Specified

MedGen UID:
233807
Concept ID:
C1335164
Neoplastic Process
Synonyms: Leydig Cell Neoplasm of Ovary; Leydig Cell Neoplasm of the Ovary; Leydig Cell Tumor of Ovary; Leydig Cell Tumor of the Ovary; Ovarian Leydig Cell Neoplasm; Ovarian Leydig Cell Tumor

Definition

A rare, benign steroid tumor that arises from the ovary and is composed of Leydig cells that contain Reinke crystals. It usually affects postmenopausal women and in most cases, is associated with androgenic manifestations. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian Leydig Cell Tumor, Not Otherwise Specified

Professional guidelines

PubMed

Han LM, Weiel JJ, Longacre TA, Folkins AK
Adv Anat Pathol 2022 Sep 1;29(5):297-308. Epub 2022 Jul 1 doi: 10.1097/PAP.0000000000000351. PMID: 35778792
Rojewska P, Meczekalski B, Bala G, Luisi S, Podfigurna A
Gynecol Endocrinol 2022 Jul;38(7):537-542. Epub 2022 Jun 1 doi: 10.1080/09513590.2022.2083104. PMID: 35647677
Gershenson DM
Gynecol Oncol 1994 Dec;55(3 Pt 2):S62-72. PMID: 7530680

Recent clinical studies

Etiology

Fresneau B, Orbach D, Faure-Conter C, Verité C, Castex MP, Kalfa N, Martelli H, Patte C
Pediatr Blood Cancer 2015 Dec;62(12):2114-9. Epub 2015 Jul 23 doi: 10.1002/pbc.25614. PMID: 26206391
McCluggage WG, McKenna M, McBride HA
Int J Gynecol Pathol 2007 Jul;26(3):322-7. doi: 10.1097/01.pgp.0000236947.59463.87. PMID: 17581419
Hayes MC, Scully RE
Am J Surg Pathol 1987 Nov;11(11):835-45. doi: 10.1097/00000478-198711000-00002. PMID: 2823622

Diagnosis

Bouzidi L, Triki M, Charfi S, Ameur HB, Dhaou MB, Bouaziz T, Boudawara T
Pediatr Dev Pathol 2021 Mar-Apr;24(2):137-141. Epub 2021 Jan 12 doi: 10.1177/1093526620980614. PMID: 33433255
Fresneau B, Orbach D, Faure-Conter C, Verité C, Castex MP, Kalfa N, Martelli H, Patte C
Pediatr Blood Cancer 2015 Dec;62(12):2114-9. Epub 2015 Jul 23 doi: 10.1002/pbc.25614. PMID: 26206391
McCluggage WG, McKenna M, McBride HA
Int J Gynecol Pathol 2007 Jul;26(3):322-7. doi: 10.1097/01.pgp.0000236947.59463.87. PMID: 17581419
Wang PH, Chao HT, Lee RC, Lai CR, Lee WL, Kwok CF, Yuan CC, Ng HT
Eur J Radiol 1998 Feb;26(3):269-73. doi: 10.1016/s0720-048x(96)01133-3. PMID: 9587754

Therapy

Fresneau B, Orbach D, Faure-Conter C, Verité C, Castex MP, Kalfa N, Martelli H, Patte C
Pediatr Blood Cancer 2015 Dec;62(12):2114-9. Epub 2015 Jul 23 doi: 10.1002/pbc.25614. PMID: 26206391

Prognosis

Fresneau B, Orbach D, Faure-Conter C, Verité C, Castex MP, Kalfa N, Martelli H, Patte C
Pediatr Blood Cancer 2015 Dec;62(12):2114-9. Epub 2015 Jul 23 doi: 10.1002/pbc.25614. PMID: 26206391
Hayes MC, Scully RE
Am J Surg Pathol 1987 Nov;11(11):835-45. doi: 10.1097/00000478-198711000-00002. PMID: 2823622

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...