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Paraganglioma-Like Dermal Melanocytic Tumor

MedGen UID:
233838
Concept ID:
C1335334
Neoplastic Process

Definition

A benign primary melanocytic tumor of the skin that presents as a dermal nodule. Morphologically, it is characterized by the presence of paraganglioma-like features that include a nested growth pattern of the tumor cells. The nests are composed of epithelioid cells and are separated by delicate fibrous strands. Cytoplasmic melanin is not present; however immunohistochemical studies have confirmed the melanocytic lineage of the tumor cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParaganglioma-Like Dermal Melanocytic Tumor

Recent clinical studies

Diagnosis

Kashima J, Motoi T, Nishimaki M, Hayashi Y, Ogawa M, Kato I, Yamada R, Tonooka A, Horiguchi SI, Funata N, Hishima T, Yoshino K
Pathol Int 2019 Aug;69(8):496-501. Epub 2019 Jul 5 doi: 10.1111/pin.12826. PMID: 31276279
Cimpean AM, Ceauşu R, Raica M
Int J Clin Exp Pathol 2009 Nov 20;3(2):222-5. PMID: 20126591Free PMC Article
Deyrup AT, Althof P, Zhou M, Morgan M, Solomon AR, Bridge JA, Weiss SW
Am J Surg Pathol 2004 Dec;28(12):1579-86. doi: 10.1097/00000478-200412000-00005. PMID: 15577676

Prognosis

Kashima J, Motoi T, Nishimaki M, Hayashi Y, Ogawa M, Kato I, Yamada R, Tonooka A, Horiguchi SI, Funata N, Hishima T, Yoshino K
Pathol Int 2019 Aug;69(8):496-501. Epub 2019 Jul 5 doi: 10.1111/pin.12826. PMID: 31276279
Deyrup AT, Althof P, Zhou M, Morgan M, Solomon AR, Bridge JA, Weiss SW
Am J Surg Pathol 2004 Dec;28(12):1579-86. doi: 10.1097/00000478-200412000-00005. PMID: 15577676

Supplemental Content

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