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Gastric T-Cell Non-Hodgkin Lymphoma

MedGen UID:
233872
•Concept ID:
C1335484
•
Neoplastic Process
Synonyms: Gastric T-Cell Non-Hodgkin's Lymphoma; Primary Gastric T-Cell Lymphoma; Primary Gastric T-Cell Non-Hodgkin's Lymphoma; Primary T-Cell Lymphoma of Stomach; Primary T-Cell Lymphoma of the Stomach

Definition

A rare, extranodal T-cell non-Hodgkin lymphoma that arises from the stomach with the bulk of the mass located in the stomach. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastric T-Cell Non-Hodgkin Lymphoma

Professional guidelines

PubMed

Clinical Implications and Management of Non-BIA-ALCL Breast Implant Capsular Pathology.
Vorstenbosch J, Chu JJ, Ariyan CE, McCarthy CM, Disa JJ, Nelson JA
Plast Reconstr Surg 2023 Jan 1;151(1):20e-30e. Epub 2022 Oct 4 doi: 10.1097/PRS.0000000000009780. PMID: 36194076Free PMC Article
Diagnosis and management of rare gastrointestinal lymphomas.
Hawkes EA, Wotherspoon A, Cunningham D
Leuk Lymphoma 2012 Dec;53(12):2341-50. Epub 2012 Jun 21 doi: 10.3109/10428194.2012.695780. PMID: 22616672
Management of non-Hodgkin lymphomas arising at extranodal sites.
Zucca E, Gregorini A, Cavalli F
Ther Umsch 2010 Oct;67(10):517-25. doi: 10.1024/0040-5930/a000088. PMID: 20886458

Recent clinical studies

Etiology

Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
CT features of peripheral T-cell lymphoma in the gastrointestinal tract in Chinese population and literature review.
Zhu L, Wu G, Ghimire P, Xu L
J Med Imaging Radiat Oncol 2012 Apr;56(2):143-50. doi: 10.1111/j.1754-9485.2011.02329.x. PMID: 22498185
Enteropathy-type T-cell lymphoma.
Zettl A, deLeeuw R, Haralambieva E, Mueller-Hermelink HK
Am J Clin Pathol 2007 May;127(5):701-6. doi: 10.1309/nw2bk1dxb0eqg55h. PMID: 17511112
Therapy of non-Hodgkin's lymphoma.
Coffey J, Hodgson DC, Gospodarowicz MK
Eur J Nucl Med Mol Imaging 2003 Jun;30 Suppl 1:S28-36. Epub 2003 Apr 12 doi: 10.1007/s00259-003-1157-6. PMID: 12692688
Gastrointestinal lymphoma.
Isaacson PG
Hum Pathol 1994 Oct;25(10):1020-9. doi: 10.1016/0046-8177(94)90060-4. PMID: 7927306

Diagnosis

Platinum-based chemotherapy in combination with PD-1/PD-L1 inhibitors: preclinical and clinical studies and mechanism of action.
Xue Y, Gao S, Gou J, Yin T, He H, Wang Y, Zhang Y, Tang X, Wu R
Expert Opin Drug Deliv 2021 Feb;18(2):187-203. Epub 2020 Oct 5 doi: 10.1080/17425247.2021.1825376. PMID: 32954856
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
The recognition and classification of lymphoproliferative disorders of the gut.
O'Malley DP, Goldstein NS, Banks PM
Hum Pathol 2014 May;45(5):899-916. Epub 2013 Dec 18 doi: 10.1016/j.humpath.2013.12.001. PMID: 24613566
FGF receptors: cancer biology and therapeutics.
Katoh M, Nakagama H
Med Res Rev 2014 Mar;34(2):280-300. Epub 2013 May 21 doi: 10.1002/med.21288. PMID: 23696246
Enteropathy-type T-cell lymphoma.
Zettl A, deLeeuw R, Haralambieva E, Mueller-Hermelink HK
Am J Clin Pathol 2007 May;127(5):701-6. doi: 10.1309/nw2bk1dxb0eqg55h. PMID: 17511112

Therapy

Odronextamab, a human CD20×CD3 bispecific antibody in patients with CD20-positive B-cell malignancies (ELM-1): results from the relapsed or refractory non-Hodgkin lymphoma cohort in a single-arm, multicentre, phase 1 trial.
Bannerji R, Arnason JE, Advani RH, Brown JR, Allan JN, Ansell SM, Barnes JA, O'Brien SM, Chávez JC, Duell J, Rosenwald A, Crombie JL, Ufkin M, Li J, Zhu M, Ambati SR, Chaudhry A, Lowy I, Topp MS
Lancet Haematol 2022 May;9(5):e327-e339. Epub 2022 Apr 1 doi: 10.1016/S2352-3026(22)00072-2. PMID: 35366963
Estimating the global burden of Epstein-Barr virus-related cancers.
Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104Free PMC Article
Platinum-based chemotherapy in combination with PD-1/PD-L1 inhibitors: preclinical and clinical studies and mechanism of action.
Xue Y, Gao S, Gou J, Yin T, He H, Wang Y, Zhang Y, Tang X, Wu R
Expert Opin Drug Deliv 2021 Feb;18(2):187-203. Epub 2020 Oct 5 doi: 10.1080/17425247.2021.1825376. PMID: 32954856
Precision medicine for human cancers with Notch signaling dysregulation (Review).
Katoh M, Katoh M
Int J Mol Med 2020 Feb;45(2):279-297. Epub 2019 Dec 4 doi: 10.3892/ijmm.2019.4418. PMID: 31894255Free PMC Article
FGF receptors: cancer biology and therapeutics.
Katoh M, Nakagama H
Med Res Rev 2014 Mar;34(2):280-300. Epub 2013 May 21 doi: 10.1002/med.21288. PMID: 23696246

Prognosis

The epidemiology and prognosis of patients with primary gastric T-cell lymphoma in the SEER program.
Zhang M, Xiao F, Lin M, Chen M, Hou J, Huang H
Cancer Med 2023 Jan;12(1):84-98. Epub 2022 Jun 13 doi: 10.1002/cam4.4936. PMID: 35698430Free PMC Article
Peripheral T-cell lymphoma with gastrointestinal involvement and indolent T-lymphoproliferative disorders of the gastrointestinal tract.
Kohri M, Tsukasaki K, Akuzawa Y, Tanae K, Takahashi N, Saeki T, Okamura D, Ishikawa M, Maeda T, Kawai N, Matsuda A, Arai E, Arai S, Asou N
Leuk Res 2020 Apr;91:106336. Epub 2020 Feb 29 doi: 10.1016/j.leukres.2020.106336. PMID: 32151888
Incidence rates and clinical characteristics of primary gastrointestinal non-Hodgkin lymphoma: a population study.
Dizengof V, Levi I, Etzion O, Fich A, Blum A, Chertok IRA, Ben-Yakov G, Rouvio O, Greenbaum U
Eur J Gastroenterol Hepatol 2020 May;32(5):569-574. doi: 10.1097/MEG.0000000000001651. PMID: 31895909
Pancreatic T/histiocyte-rich large B-cell lymphoma: A case report and review of literature.
Zheng SM, Zhou DJ, Chen YH, Jiang R, Wang YX, Zhang Y, Xue HL, Wang HQ, Mou D, Zeng WZ
World J Gastroenterol 2017 Jun 28;23(24):4467-4472. doi: 10.3748/wjg.v23.i24.4467. PMID: 28706431Free PMC Article
Gastrointestinal lymphoma.
Isaacson PG
Hum Pathol 1994 Oct;25(10):1020-9. doi: 10.1016/0046-8177(94)90060-4. PMID: 7927306

Clinical prediction guides

Odronextamab, a human CD20×CD3 bispecific antibody in patients with CD20-positive B-cell malignancies (ELM-1): results from the relapsed or refractory non-Hodgkin lymphoma cohort in a single-arm, multicentre, phase 1 trial.
Bannerji R, Arnason JE, Advani RH, Brown JR, Allan JN, Ansell SM, Barnes JA, O'Brien SM, Chávez JC, Duell J, Rosenwald A, Crombie JL, Ufkin M, Li J, Zhu M, Ambati SR, Chaudhry A, Lowy I, Topp MS
Lancet Haematol 2022 May;9(5):e327-e339. Epub 2022 Apr 1 doi: 10.1016/S2352-3026(22)00072-2. PMID: 35366963
Estimating the global burden of Epstein-Barr virus-related cancers.
Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104Free PMC Article
Platinum-based chemotherapy in combination with PD-1/PD-L1 inhibitors: preclinical and clinical studies and mechanism of action.
Xue Y, Gao S, Gou J, Yin T, He H, Wang Y, Zhang Y, Tang X, Wu R
Expert Opin Drug Deliv 2021 Feb;18(2):187-203. Epub 2020 Oct 5 doi: 10.1080/17425247.2021.1825376. PMID: 32954856
Monomorphic Epitheliotropic Intestinal T-cell Lymphoma of the Stomach: Two Case Reports and a Literature Review.
Lu S, Zhou G, Chen M, Liu W, Zhao S
Int J Surg Pathol 2021 Jun;29(4):410-419. Epub 2020 Aug 28 doi: 10.1177/1066896920953906. PMID: 32856508
Exposing Hidden Targets: Combining epigenetic and immunotherapy to overcome cancer resistance.
Olino K, Park T, Ahuja N
Semin Cancer Biol 2020 Oct;65:114-122. Epub 2020 Jan 3 doi: 10.1016/j.semcancer.2020.01.001. PMID: 31911188

Recent systematic reviews

Association between HTLV-1 infection and adverse health outcomes: a systematic review and meta-analysis of epidemiological studies.
Schierhout G, McGregor S, Gessain A, Einsiedel L, Martinello M, Kaldor J
Lancet Infect Dis 2020 Jan;20(1):133-143. Epub 2019 Oct 21 doi: 10.1016/S1473-3099(19)30402-5. PMID: 31648940
Gastrosplenic fistula occurring in lymphoma patients: Systematic review with a new case of extranodal NK/T-cell lymphoma.
Kang DH, Huh J, Lee JH, Jeong YK, Cha HJ
World J Gastroenterol 2017 Sep 21;23(35):6491-6499. doi: 10.3748/wjg.v23.i35.6491. PMID: 29085199Free PMC Article

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