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Breast Small Cell Neuroendocrine Carcinoma

MedGen UID:
234053
Concept ID:
C1332638
Neoplastic Process
Synonyms: Breast Small Cell Carcinoma; Small Cell Carcinoma of Breast; Small Cell Carcinoma of the Breast; Small Cell Neuroendocrine Carcinoma of Breast; Small Cell Neuroendocrine Carcinoma of the Breast

Definition

A poorly differentiated neuroendocrine carcinoma that arises from the breast. It is characterized by the presence of small neuroendocrine cells and high mitotic activity. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast Small Cell Neuroendocrine Carcinoma

Professional guidelines

PubMed

Hendriks LE, Kerr KM, Menis J, Mok TS, Nestle U, Passaro A, Peters S, Planchard D, Smit EF, Solomon BJ, Veronesi G, Reck M; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Apr;34(4):339-357. Epub 2023 Jan 23 doi: 10.1016/j.annonc.2022.12.009. PMID: 36872130
Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393
Garcia J, Hurwitz HI, Sandler AB, Miles D, Coleman RL, Deurloo R, Chinot OL
Cancer Treat Rev 2020 Jun;86:102017. Epub 2020 Mar 26 doi: 10.1016/j.ctrv.2020.102017. PMID: 32335505

Recent clinical studies

Etiology

Mosele F, Remon J, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M, Meric-Bernstam F, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Bièche I, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, André F
Ann Oncol 2020 Nov;31(11):1491-1505. Epub 2020 Aug 24 doi: 10.1016/j.annonc.2020.07.014. PMID: 32853681
Shersher DD, Liptay MJ
Cancer J 2015 Jan-Feb;21(1):17-20. doi: 10.1097/PPO.0000000000000089. PMID: 25611775
Trinh VA, Hwu WJ
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Molina Garrido MJ, Guillén Ponce C, Soto Martínez JL, Martínez Y Sevila C, Carrato Mena A
Clin Transl Oncol 2006 May;8(5):330-3. doi: 10.1007/s12094-006-0178-6. PMID: 16760007
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Diagnosis

Katayama R, Sakashita T, Yanagitani N, Ninomiya H, Horiike A, Friboulet L, Gainor JF, Motoi N, Dobashi A, Sakata S, Tambo Y, Kitazono S, Sato S, Koike S, John Iafrate A, Mino-Kenudson M, Ishikawa Y, Shaw AT, Engelman JA, Takeuchi K, Nishio M, Fujita N
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Kwekkeboom DJ, Krenning EP
Semin Nucl Med 2002 Apr;32(2):84-91. doi: 10.1053/snuc.2002.31022. PMID: 11965603
O'Byrne KJ, Carney DN
Anticancer Drugs 1996 Jan;7 Suppl 1:33-44. doi: 10.1097/00001813-199601001-00006. PMID: 8822083
Pinsky SM, Henkin RE
Semin Nucl Med 1976 Oct;6(4):397-409. doi: 10.1016/s0001-2998(76)80017-7. PMID: 185721
Jones SE, Salmon SE
Semin Nucl Med 1976 Oct;6(4):331-46. doi: 10.1016/s0001-2998(76)80012-8. PMID: 62399

Therapy

Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393
Mosele F, Remon J, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M, Meric-Bernstam F, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Bièche I, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, André F
Ann Oncol 2020 Nov;31(11):1491-1505. Epub 2020 Aug 24 doi: 10.1016/j.annonc.2020.07.014. PMID: 32853681
Garcia J, Hurwitz HI, Sandler AB, Miles D, Coleman RL, Deurloo R, Chinot OL
Cancer Treat Rev 2020 Jun;86:102017. Epub 2020 Mar 26 doi: 10.1016/j.ctrv.2020.102017. PMID: 32335505
Gao H, Korn JM, Ferretti S, Monahan JE, Wang Y, Singh M, Zhang C, Schnell C, Yang G, Zhang Y, Balbin OA, Barbe S, Cai H, Casey F, Chatterjee S, Chiang DY, Chuai S, Cogan SM, Collins SD, Dammassa E, Ebel N, Embry M, Green J, Kauffmann A, Kowal C, Leary RJ, Lehar J, Liang Y, Loo A, Lorenzana E, Robert McDonald E 3rd, McLaughlin ME, Merkin J, Meyer R, Naylor TL, Patawaran M, Reddy A, Röelli C, Ruddy DA, Salangsang F, Santacroce F, Singh AP, Tang Y, Tinetto W, Tobler S, Velazquez R, Venkatesan K, Von Arx F, Wang HQ, Wang Z, Wiesmann M, Wyss D, Xu F, Bitter H, Atadja P, Lees E, Hofmann F, Li E, Keen N, Cozens R, Jensen MR, Pryer NK, Williams JA, Sellers WR
Nat Med 2015 Nov;21(11):1318-25. Epub 2015 Oct 19 doi: 10.1038/nm.3954. PMID: 26479923
Crown J, O'Leary M
Lancet 2000 Apr 1;355(9210):1176-8. doi: 10.1016/S0140-6736(00)02074-2. PMID: 10791395

Prognosis

Hendriks LE, Kerr KM, Menis J, Mok TS, Nestle U, Passaro A, Peters S, Planchard D, Smit EF, Solomon BJ, Veronesi G, Reck M; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Apr;34(4):339-357. Epub 2023 Jan 23 doi: 10.1016/j.annonc.2022.12.009. PMID: 36872130
Hendriks LE, Kerr KM, Menis J, Mok TS, Nestle U, Passaro A, Peters S, Planchard D, Smit EF, Solomon BJ, Veronesi G, Reck M; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Apr;34(4):358-376. Epub 2023 Jan 17 doi: 10.1016/j.annonc.2022.12.013. PMID: 36669645
McMahon JT, Faraj RR, Adamson DC
Expert Opin Investig Drugs 2020 Dec;29(12):1389-1406. Epub 2020 Oct 26 doi: 10.1080/13543784.2020.1836154. PMID: 33040640
Zhang Q, Lu S, Li T, Yu L, Zhang Y, Zeng H, Qian X, Bi J, Lin Y
J Exp Clin Cancer Res 2019 Apr 25;38(1):173. doi: 10.1186/s13046-019-1156-5. PMID: 31023337Free PMC Article
Nayak L, Lee EQ, Wen PY
Curr Oncol Rep 2012 Feb;14(1):48-54. doi: 10.1007/s11912-011-0203-y. PMID: 22012633

Clinical prediction guides

Trincado JL, Reixachs-Solé M, Pérez-Granado J, Fugmann T, Sanz F, Yokota J, Eyras E
PLoS Comput Biol 2021 Sep;17(9):e1009411. Epub 2021 Sep 16 doi: 10.1371/journal.pcbi.1009411. PMID: 34529669Free PMC Article
Mosele F, Remon J, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M, Meric-Bernstam F, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Bièche I, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, André F
Ann Oncol 2020 Nov;31(11):1491-1505. Epub 2020 Aug 24 doi: 10.1016/j.annonc.2020.07.014. PMID: 32853681
Zhang Q, Lu S, Li T, Yu L, Zhang Y, Zeng H, Qian X, Bi J, Lin Y
J Exp Clin Cancer Res 2019 Apr 25;38(1):173. doi: 10.1186/s13046-019-1156-5. PMID: 31023337Free PMC Article
Hendry S, Salgado R, Gevaert T, Russell PA, John T, Thapa B, Christie M, van de Vijver K, Estrada MV, Gonzalez-Ericsson PI, Sanders M, Solomon B, Solinas C, Van den Eynden GGGM, Allory Y, Preusser M, Hainfellner J, Pruneri G, Vingiani A, Demaria S, Symmans F, Nuciforo P, Comerma L, Thompson EA, Lakhani S, Kim SR, Schnitt S, Colpaert C, Sotiriou C, Scherer SJ, Ignatiadis M, Badve S, Pierce RH, Viale G, Sirtaine N, Penault-Llorca F, Sugie T, Fineberg S, Paik S, Srinivasan A, Richardson A, Wang Y, Chmielik E, Brock J, Johnson DB, Balko J, Wienert S, Bossuyt V, Michiels S, Ternes N, Burchardi N, Luen SJ, Savas P, Klauschen F, Watson PH, Nelson BH, Criscitiello C, O'Toole S, Larsimont D, de Wind R, Curigliano G, André F, Lacroix-Triki M, van de Vijver M, Rojo F, Floris G, Bedri S, Sparano J, Rimm D, Nielsen T, Kos Z, Hewitt S, Singh B, Farshid G, Loibl S, Allison KH, Tung N, Adams S, Willard-Gallo K, Horlings HM, Gandhi L, Moreira A, Hirsch F, Dieci MV, Urbanowicz M, Brcic I, Korski K, Gaire F, Koeppen H, Lo A, Giltnane J, Rebelatto MC, Steele KE, Zha J, Emancipator K, Juco JW, Denkert C, Reis-Filho J, Loi S, Fox SB
Adv Anat Pathol 2017 Nov;24(6):311-335. doi: 10.1097/PAP.0000000000000161. PMID: 28777143Free PMC Article
Jones SE, Salmon SE
Semin Nucl Med 1976 Oct;6(4):331-46. doi: 10.1016/s0001-2998(76)80012-8. PMID: 62399

Recent systematic reviews

Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393
Tonneau M, Mouttet-Audouard R, Le Tinier F, Mirabel X, Pasquier D
BMC Cancer 2021 Oct 30;21(1):1168. doi: 10.1186/s12885-021-08901-6. PMID: 34717570Free PMC Article
Zhang Y, Cao J, Deng Y, Huang Y, Li R, Lin G, Dong M, Huang Z
Clinics (Sao Paulo) 2020;75:e993. Epub 2020 Feb 27 doi: 10.6061/clinics/2020/e993. PMID: 32130355Free PMC Article
Spano G, Stutz E, Elicin O, Hugi B, Henzen D, Fürholz M, Wieser M, Rhyner D, Dobner S, Pavlicek-Bahlo M, Robson D, Nadel J, Hayward C, Hunziker L, Martinelli M, Schnegg B
Artif Organs 2020 May;44(5):449-456. Epub 2020 Jan 15 doi: 10.1111/aor.13612. PMID: 31769042
Treasure T
Eur J Cardiothorac Surg 2008 Feb;33(2):300-2. Epub 2007 Dec 11 doi: 10.1016/j.ejcts.2007.10.015. PMID: 18065234

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