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Cervical clear cell adenocarcinoma

MedGen UID:
234113
Concept ID:
C1332912
Neoplastic Process
Synonyms: Cervical Clear Cell Adenocarcinoma; cervical clear cell adenocarcinoma; Cervical Clear Cell Carcinoma; cervical clear cell carcinoma; Cervix Clear Cell Adenocarcinoma; cervix clear cell adenocarcinoma; Cervix Clear Cell Carcinoma; cervix clear cell carcinoma; Cervix Uteri Clear Cell Adenocarcinoma; cervix uteri clear cell adenocarcinoma; Cervix Uteri Clear Cell Carcinoma; cervix uteri clear cell carcinoma; Clear Cell Adenocarcinoma of Cervix; clear cell adenocarcinoma of cervix; Clear Cell Adenocarcinoma of Cervix Uteri; clear cell adenocarcinoma of cervix uteri; Clear Cell Adenocarcinoma of the Cervix; clear cell adenocarcinoma of the cervix; Clear Cell Adenocarcinoma of the Cervix Uteri; clear cell adenocarcinoma of the cervix uteri; Clear Cell Adenocarcinoma of the Uterine Cervix; clear cell adenocarcinoma of the uterine cervix; Clear Cell Adenocarcinoma of Uterine Cervix; clear cell adenocarcinoma of uterine cervix; Clear Cell Carcinoma of Cervix; Clear cell carcinoma of cervix; clear cell carcinoma of cervix; Clear Cell Carcinoma of Cervix Uteri; clear cell carcinoma of cervix uteri; Clear Cell Carcinoma of the Cervix; clear cell carcinoma of the cervix; Clear Cell Carcinoma of the Cervix Uteri; clear cell carcinoma of the cervix uteri; Clear Cell Carcinoma of the Uterine Cervix; clear cell carcinoma of the uterine cervix; Clear Cell Carcinoma of Uterine Cervix; clear cell carcinoma of uterine cervix; HPV- Independent Cervical Adenocarcinoma, Clear Cell Type; HPV- Independent Cervical Adenocarcinoma, Clear Cell-Type; Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell Type; Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type; Uterine Cervix Clear Cell Adenocarcinoma; uterine cervix clear cell adenocarcinoma; Uterine Cervix Clear Cell Carcinoma; uterine cervix clear cell carcinoma
 
HPO: HP:0031522
Monarch Initiative: MONDO:0006135

Definition

A type of adenocarcinoma originating in the cervix and characterized by large cells with moderate to abundant clear cytoplasm. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCervical clear cell adenocarcinoma

Professional guidelines

PubMed

Griesinger LM, Szczepanski JM, McMullen ER, Skala SL
Arch Pathol Lab Med 2021 Jul 1;145(7):891-902. doi: 10.5858/arpa.2020-0327-RA. PMID: 33091926
Stolnicu S, Barsan I, Hoang L, Patel P, Terinte C, Pesci A, Aviel-Ronen S, Kiyokawa T, Alvarado-Cabrero I, Pike MC, Oliva E, Park KJ, Soslow RA
Am J Surg Pathol 2018 Feb;42(2):214-226. doi: 10.1097/PAS.0000000000000986. PMID: 29135516Free PMC Article
Skálová A, Stenman G, Simpson RHW, Hellquist H, Slouka D, Svoboda T, Bishop JA, Hunt JL, Nibu KI, Rinaldo A, Vander Poorten V, Devaney KO, Steiner P, Ferlito A
Am J Surg Pathol 2018 Feb;42(2):e11-e27. doi: 10.1097/PAS.0000000000000980. PMID: 29076877

Recent clinical studies

Etiology

Liu Y, Shi X, Yang J, Zhou H, Peng P, Cao D
Technol Cancer Res Treat 2023 Jan-Dec;22:15330338221149297. doi: 10.1177/15330338221149297. PMID: 36718531Free PMC Article
Huo D, Anderson D, Palmer JR, Herbst AL
Gynecol Oncol 2017 Sep;146(3):566-571. Epub 2017 Jul 6 doi: 10.1016/j.ygyno.2017.06.028. PMID: 28689666
Guo Y, Song L, Liu H
J Pediatr Adolesc Gynecol 2014 Feb;27(1):e1-3. Epub 2013 Jul 10 doi: 10.1016/j.jpag.2013.04.007. PMID: 23849091
Wilkinson EJ
Curr Opin Obstet Gynecol 1991 Aug;3(4):553-60. PMID: 1678972
IARC Monogr Eval Carcinog Risk Chem Hum 1979 Dec;21:173-231. PMID: 397181

Diagnosis

Liu Y, Shi X, Yang J, Zhou H, Peng P, Cao D
Technol Cancer Res Treat 2023 Jan-Dec;22:15330338221149297. doi: 10.1177/15330338221149297. PMID: 36718531Free PMC Article
Huo D, Anderson D, Palmer JR, Herbst AL
Gynecol Oncol 2017 Sep;146(3):566-571. Epub 2017 Jul 6 doi: 10.1016/j.ygyno.2017.06.028. PMID: 28689666
Guo Y, Song L, Liu H
J Pediatr Adolesc Gynecol 2014 Feb;27(1):e1-3. Epub 2013 Jul 10 doi: 10.1016/j.jpag.2013.04.007. PMID: 23849091
Hanselaar AG, Van Leusen ND, De Wilde PC, Vooijs GP
Cancer 1991 Apr 1;67(7):1971-8. doi: 10.1002/1097-0142(19910401)67:7<1971::aid-cncr2820670725>3.0.co;2-x. PMID: 2004313
Wilkinson EJ
Curr Opin Obstet Gynecol 1991 Aug;3(4):553-60. PMID: 1678972

Therapy

Huo D, Anderson D, Palmer JR, Herbst AL
Gynecol Oncol 2017 Sep;146(3):566-571. Epub 2017 Jul 6 doi: 10.1016/j.ygyno.2017.06.028. PMID: 28689666
Guo Y, Song L, Liu H
J Pediatr Adolesc Gynecol 2014 Feb;27(1):e1-3. Epub 2013 Jul 10 doi: 10.1016/j.jpag.2013.04.007. PMID: 23849091
Hanselaar AG, Boss EA, Massuger LF, Bernheim JL
Gynecol Oncol 1999 Dec;75(3):338-44. doi: 10.1006/gyno.1999.5637. PMID: 10600286
Hanselaar AG, Van Leusen ND, De Wilde PC, Vooijs GP
Cancer 1991 Apr 1;67(7):1971-8. doi: 10.1002/1097-0142(19910401)67:7<1971::aid-cncr2820670725>3.0.co;2-x. PMID: 2004313
IARC Monogr Eval Carcinog Risk Chem Hum 1979 Dec;21:173-231. PMID: 397181

Prognosis

Liu Y, Shi X, Yang J, Zhou H, Peng P, Cao D
Technol Cancer Res Treat 2023 Jan-Dec;22:15330338221149297. doi: 10.1177/15330338221149297. PMID: 36718531Free PMC Article
Huo D, Anderson D, Palmer JR, Herbst AL
Gynecol Oncol 2017 Sep;146(3):566-571. Epub 2017 Jul 6 doi: 10.1016/j.ygyno.2017.06.028. PMID: 28689666
Hanselaar AG, Van Leusen ND, De Wilde PC, Vooijs GP
Cancer 1991 Apr 1;67(7):1971-8. doi: 10.1002/1097-0142(19910401)67:7<1971::aid-cncr2820670725>3.0.co;2-x. PMID: 2004313

Clinical prediction guides

Liu Y, Shi X, Yang J, Zhou H, Peng P, Cao D
Technol Cancer Res Treat 2023 Jan-Dec;22:15330338221149297. doi: 10.1177/15330338221149297. PMID: 36718531Free PMC Article

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