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Childhood anaplastic large cell lymphoma

MedGen UID:
234120
•Concept ID:
C1332942
•
Neoplastic Process
Synonyms: Childhood Anaplastic Large Cell Lymphoma; Childhood CD30+ Anaplastic Large Cell Lymphoma; Childhood K-1+ Anaplastic Large Cell Lymphoma; Pediatric Anaplastic Large Cell Lymphoma; Pediatric CD30+ Anaplastic Large Cell Lymphoma; Pediatric K-1+ Anaplastic Large Cell Lymphoma

Definition

An anaplastic large cell lymphoma that occurs during childhood. [from NCI]

Professional guidelines

PubMed

Relapses of childhood anaplastic large-cell lymphoma: treatment results in a series of 41 children--a report from the French Society of Pediatric Oncology.
Brugières L, Quartier P, Le Deley MC, Pacquement H, Perel Y, Bergeron C, Schmitt C, Landmann J, Patte C, Terrier-Lacombe MJ, Delsol G, Hartmann O
Ann Oncol 2000 Jan;11(1):53-8. doi: 10.1023/a:1008352726155. PMID: 10690387

Recent clinical studies

Etiology

Outcome and prognosis of anaplastic large cell lymphoma in children: a report from the Taiwan Pediatric Oncology Group.
Chen SH, Chen JS, Jou ST, Wu KH, Hung IJ, Sheen JM, Lu MY, Chen BW, Jaing TH, Wang SC, Lin MT, Chang TK, Liu HC, Yang CP
Leuk Lymphoma 2019 Aug;60(8):1942-1949. Epub 2019 Jan 15 doi: 10.1080/10428194.2018.1562182. PMID: 30646784
Limited stage I disease is not necessarily indicative of an excellent prognosis in childhood anaplastic large cell lymphoma.
Attarbaschi A, Mann G, Rosolen A, Williams D, Uyttebroeck A, Marky I, Lamant L, Horibe K, Wrobel G, Beishuizen A, Wössmann W, Reiter A, Mauguen A, Le Deley MC, Brugières L; European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) ALCL99 Trial
Blood 2011 May 26;117(21):5616-9. Epub 2011 Mar 28 doi: 10.1182/blood-2010-12-324012. PMID: 21444917
Prognostic factors in childhood anaplastic large cell lymphoma: results of a large European intergroup study.
Le Deley MC, Reiter A, Williams D, Delsol G, Oschlies I, McCarthy K, Zimmermann M, Brugières L; European Intergroup for Childhood Non-Hodgkin Lymphoma
Blood 2008 Feb 1;111(3):1560-6. Epub 2007 Oct 23 doi: 10.1182/blood-2007-07-100958. PMID: 17957029
Recurrent childhood anaplastic large cell lymphoma: a retrospective analysis of registered cases in Japan.
Mori T, Takimoto T, Katano N, Kikuchi A, Tabuchi K, Kobayashi R, Ayukawa H, Kumagai MA, Horibe K, Tsurusawa M
Br J Haematol 2006 Mar;132(5):594-7. doi: 10.1111/j.1365-2141.2005.05910.x. PMID: 16445832
Childhood anaplastic large cell lymphoma Ki-1/CD30: clinicopathologic features of 19 cases.
Rubie H, Gladieff L, Robert A, Gaubert I, Huguet F, Rochaix P, Pein F, Michel G, Hoerni B, Sommelet D
Med Pediatr Oncol 1994;22(3):155-61. doi: 10.1002/mpo.2950220302. PMID: 8272005

Diagnosis

Outcome and prognosis of anaplastic large cell lymphoma in children: a report from the Taiwan Pediatric Oncology Group.
Chen SH, Chen JS, Jou ST, Wu KH, Hung IJ, Sheen JM, Lu MY, Chen BW, Jaing TH, Wang SC, Lin MT, Chang TK, Liu HC, Yang CP
Leuk Lymphoma 2019 Aug;60(8):1942-1949. Epub 2019 Jan 15 doi: 10.1080/10428194.2018.1562182. PMID: 30646784
Recurrent childhood anaplastic large cell lymphoma: a retrospective analysis of registered cases in Japan.
Mori T, Takimoto T, Katano N, Kikuchi A, Tabuchi K, Kobayashi R, Ayukawa H, Kumagai MA, Horibe K, Tsurusawa M
Br J Haematol 2006 Mar;132(5):594-7. doi: 10.1111/j.1365-2141.2005.05910.x. PMID: 16445832
Anaplastic large cell lymphoma treated with a leukemia-like therapy: report of the Italian Association of Pediatric Hematology and Oncology (AIEOP) LNH-92 protocol.
Rosolen A, Pillon M, Garaventa A, Burnelli R, d'Amore ES, Giuliano M, Comis M, Cesaro S, Tettoni K, Moleti ML, Tamaro P, Visintin G, Zanesco L
Cancer 2005 Nov 15;104(10):2133-40. doi: 10.1002/cncr.21438. PMID: 16211546
CD30(+) anaplastic large-cell lymphoma in children: analysis of 82 patients enrolled in two consecutive studies of the French Society of Pediatric Oncology.
Brugières L, Deley MC, Pacquement H, Meguerian-Bedoyan Z, Terrier-Lacombe MJ, Robert A, Pondarré C, Leverger G, Devalck C, Rodary C, Delsol G, Hartmann O
Blood 1998 Nov 15;92(10):3591-8. PMID: 9808552
Childhood anaplastic large cell lymphoma Ki-1/CD30: clinicopathologic features of 19 cases.
Rubie H, Gladieff L, Robert A, Gaubert I, Huguet F, Rochaix P, Pein F, Michel G, Hoerni B, Sommelet D
Med Pediatr Oncol 1994;22(3):155-61. doi: 10.1002/mpo.2950220302. PMID: 8272005

Therapy

Limited stage I disease is not necessarily indicative of an excellent prognosis in childhood anaplastic large cell lymphoma.
Attarbaschi A, Mann G, Rosolen A, Williams D, Uyttebroeck A, Marky I, Lamant L, Horibe K, Wrobel G, Beishuizen A, Wössmann W, Reiter A, Mauguen A, Le Deley MC, Brugières L; European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) ALCL99 Trial
Blood 2011 May 26;117(21):5616-9. Epub 2011 Mar 28 doi: 10.1182/blood-2010-12-324012. PMID: 21444917
Safety assessment of intensive induction therapy in childhood anaplastic large cell lymphoma: report of the ALCL99 randomised trial.
Wrobel G, Mauguen A, Rosolen A, Reiter A, Williams D, Horibe K, Brugières L, Le Deley MC; European Inter-Group for Childhood, Non-Hodgkin Lymphoma (EICNHL)
Pediatr Blood Cancer 2011 Jul 1;56(7):1071-7. Epub 2011 Jan 28 doi: 10.1002/pbc.22940. PMID: 21280197
Recurrent childhood anaplastic large cell lymphoma: a retrospective analysis of registered cases in Japan.
Mori T, Takimoto T, Katano N, Kikuchi A, Tabuchi K, Kobayashi R, Ayukawa H, Kumagai MA, Horibe K, Tsurusawa M
Br J Haematol 2006 Mar;132(5):594-7. doi: 10.1111/j.1365-2141.2005.05910.x. PMID: 16445832
Anaplastic large cell lymphoma treated with a leukemia-like therapy: report of the Italian Association of Pediatric Hematology and Oncology (AIEOP) LNH-92 protocol.
Rosolen A, Pillon M, Garaventa A, Burnelli R, d'Amore ES, Giuliano M, Comis M, Cesaro S, Tettoni K, Moleti ML, Tamaro P, Visintin G, Zanesco L
Cancer 2005 Nov 15;104(10):2133-40. doi: 10.1002/cncr.21438. PMID: 16211546
Childhood anaplastic large cell lymphoma Ki-1/CD30: clinicopathologic features of 19 cases.
Rubie H, Gladieff L, Robert A, Gaubert I, Huguet F, Rochaix P, Pein F, Michel G, Hoerni B, Sommelet D
Med Pediatr Oncol 1994;22(3):155-61. doi: 10.1002/mpo.2950220302. PMID: 8272005

Prognosis

Outcome and prognosis of anaplastic large cell lymphoma in children: a report from the Taiwan Pediatric Oncology Group.
Chen SH, Chen JS, Jou ST, Wu KH, Hung IJ, Sheen JM, Lu MY, Chen BW, Jaing TH, Wang SC, Lin MT, Chang TK, Liu HC, Yang CP
Leuk Lymphoma 2019 Aug;60(8):1942-1949. Epub 2019 Jan 15 doi: 10.1080/10428194.2018.1562182. PMID: 30646784
Limited stage I disease is not necessarily indicative of an excellent prognosis in childhood anaplastic large cell lymphoma.
Attarbaschi A, Mann G, Rosolen A, Williams D, Uyttebroeck A, Marky I, Lamant L, Horibe K, Wrobel G, Beishuizen A, Wössmann W, Reiter A, Mauguen A, Le Deley MC, Brugières L; European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) ALCL99 Trial
Blood 2011 May 26;117(21):5616-9. Epub 2011 Mar 28 doi: 10.1182/blood-2010-12-324012. PMID: 21444917
Prognostic factors in childhood anaplastic large cell lymphoma: results of a large European intergroup study.
Le Deley MC, Reiter A, Williams D, Delsol G, Oschlies I, McCarthy K, Zimmermann M, Brugières L; European Intergroup for Childhood Non-Hodgkin Lymphoma
Blood 2008 Feb 1;111(3):1560-6. Epub 2007 Oct 23 doi: 10.1182/blood-2007-07-100958. PMID: 17957029
Recurrent childhood anaplastic large cell lymphoma: a retrospective analysis of registered cases in Japan.
Mori T, Takimoto T, Katano N, Kikuchi A, Tabuchi K, Kobayashi R, Ayukawa H, Kumagai MA, Horibe K, Tsurusawa M
Br J Haematol 2006 Mar;132(5):594-7. doi: 10.1111/j.1365-2141.2005.05910.x. PMID: 16445832
Anaplastic large cell lymphoma treated with a leukemia-like therapy: report of the Italian Association of Pediatric Hematology and Oncology (AIEOP) LNH-92 protocol.
Rosolen A, Pillon M, Garaventa A, Burnelli R, d'Amore ES, Giuliano M, Comis M, Cesaro S, Tettoni K, Moleti ML, Tamaro P, Visintin G, Zanesco L
Cancer 2005 Nov 15;104(10):2133-40. doi: 10.1002/cncr.21438. PMID: 16211546

Clinical prediction guides

Two Relapsed Stage III Childhood Anaplastic Large Cell Lymphoma Patients with NPM-ALK Fusion in Bone Marrow from Initial Diagnosis.
Kanazawa Y, Yamashita Y, Fujiwara M, Muraoka M, Washio K, Kanamitsu K, Ishida H, Nakano T, Yamada M, Horibe K, Tanaka T, Yoshino T, Shimada A
Acta Med Okayama 2016 Dec;70(6):503-506. doi: 10.18926/AMO/54815. PMID: 28003677
Monoallelic mutations of the perforin gene may represent a predisposing factor to childhood anaplastic large cell lymphoma.
Ciambotti B, Mussolin L, d'Amore ES, Pillon M, Sieni E, Coniglio ML, Ros MD, Cetica V, Aricò M, Rosolen A
J Pediatr Hematol Oncol 2014 Aug;36(6):e359-65. doi: 10.1097/MPH.0000000000000073. PMID: 24309606
Germline mutations of the perforin gene are a frequent occurrence in childhood anaplastic large cell lymphoma.
Cannella S, Santoro A, Bruno G, Pillon M, Mussolin L, Mangili G, Rosolen A, Aricò M
Cancer 2007 Jun 15;109(12):2566-71. doi: 10.1002/cncr.22718. PMID: 17477373
CD30(+) anaplastic large-cell lymphoma in children: analysis of 82 patients enrolled in two consecutive studies of the French Society of Pediatric Oncology.
Brugières L, Deley MC, Pacquement H, Meguerian-Bedoyan Z, Terrier-Lacombe MJ, Robert A, Pondarré C, Leverger G, Devalck C, Rodary C, Delsol G, Hartmann O
Blood 1998 Nov 15;92(10):3591-8. PMID: 9808552

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