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Colon neuroendocrine neoplasm

MedGen UID:
234162
Concept ID:
C1333097
Neoplastic Process
Synonyms: colon NET; Colon Neuroendocrine Neoplasm; colon neuroendocrine neoplasm; colon neuroendocrine tumor; colon neuroendocrine tumor, well differentiated, low or intermediate grade; colon neuroendocrine tumour; Colonic NET; Colonic Neuroendocrine Neoplasm; colonic neuroendocrine neoplasm; colonic neuroendocrine tumor; colonic neuroendocrine tumour; NET of the colon; Neuroendocrine neoplasm of colon; Neuroendocrine Neoplasm of Colon; neuroendocrine neoplasm of colon; Neuroendocrine Neoplasm of the Colon; Neuroendocrine neoplasm of the colon; neuroendocrine neoplasm of the colon; neuroendocrine tumor of the colon; Neuroendocrine tumor of the colon; neuroendocrine tumour of the colon
SNOMED CT: Neuroendocrine neoplasm of colon (1162856006)
 
Monarch Initiative: MONDO:0002882
Orphanet: ORPHA100080

Definition

A rare epithelial tumor of the large intestine, arising from enterochromaffin cells, most commonly in the cecum or ascending colon. The tumor is usually slow-growing and can be diagnosed as an incidental finding in an asymptomatic patient, while in the later stages patients can present with abdominal pain, palpable abdominal mass, changes in bowel habits, signs of bowel obstruction, gastrointestinal bleeding, anorexia, weight loss or, rarely, carcinoid syndrome (facial flushing, diarrhea, tachycardia, hypo- and hypertension, cardiac abnormalities). [from ORDO]

Professional guidelines

PubMed

Singh V, Sheikh A, Abourehab MAS, Kesharwani P
Biosensors (Basel) 2022 Aug 8;12(8) doi: 10.3390/bios12080617. PMID: 36005013Free PMC Article
Gonzalez RS
Surg Pathol Clin 2020 Sep;13(3):377-397. doi: 10.1016/j.path.2020.04.002. PMID: 32773190
Miller KD, Siegel RL, Lin CC, Mariotto AB, Kramer JL, Rowland JH, Stein KD, Alteri R, Jemal A
CA Cancer J Clin 2016 Jul;66(4):271-89. Epub 2016 Jun 2 doi: 10.3322/caac.21349. PMID: 27253694

Recent clinical studies

Etiology

Xu R, Zhou B, Hu P, Xue B, Gu D, Li X, Tang Q
World J Surg Oncol 2021 Aug 7;19(1):233. doi: 10.1186/s12957-021-02338-8. PMID: 34364382Free PMC Article

Diagnosis

AlSaffar A, Wood S, AlRabiy F, Hamie D, Termos S
Am J Case Rep 2022 Jan 11;23:e933792. doi: 10.12659/AJCR.933792. PMID: 35013091Free PMC Article
Xu R, Zhou B, Hu P, Xue B, Gu D, Li X, Tang Q
World J Surg Oncol 2021 Aug 7;19(1):233. doi: 10.1186/s12957-021-02338-8. PMID: 34364382Free PMC Article

Therapy

Xu R, Zhou B, Hu P, Xue B, Gu D, Li X, Tang Q
World J Surg Oncol 2021 Aug 7;19(1):233. doi: 10.1186/s12957-021-02338-8. PMID: 34364382Free PMC Article

Prognosis

Xu R, Zhou B, Hu P, Xue B, Gu D, Li X, Tang Q
World J Surg Oncol 2021 Aug 7;19(1):233. doi: 10.1186/s12957-021-02338-8. PMID: 34364382Free PMC Article

Clinical prediction guides

Xu R, Zhou B, Hu P, Xue B, Gu D, Li X, Tang Q
World J Surg Oncol 2021 Aug 7;19(1):233. doi: 10.1186/s12957-021-02338-8. PMID: 34364382Free PMC Article

Supplemental Content

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