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Testicular Mixed Embryonal Carcinoma and Teratoma with Seminoma

MedGen UID:
234420
Concept ID:
C1336717
Neoplastic Process
Synonyms: Mixed Embryonal Carcinoma and Teratoma with Seminoma of Testis; Mixed Embryonal Carcinoma and Teratoma with Seminoma of the Testis

Definition

A malignant mixed germ cell tumor arising from the testis. It is characterized by the presence of a mixture of embryonal carcinoma, a teratomatous component, and a seminomatous component. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTesticular Mixed Embryonal Carcinoma and Teratoma with Seminoma

Professional guidelines

PubMed

Rougemont AL, Tille JC
Hum Pathol 2018 Nov;81:26-36. Epub 2018 May 16 doi: 10.1016/j.humpath.2018.04.025. PMID: 29753846
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467
Oliver RT
Cancer Surv 1990;9(2):333-68. PMID: 1964626

Recent clinical studies

Etiology

Wu P, Yang Y, Yu Z, Zhao L, Feng S
J Surg Res 2023 Aug;288:362-371. Epub 2023 Apr 14 doi: 10.1016/j.jss.2023.03.018. PMID: 37062232
Gondim DD, Ulbright TM, Cheng L, Idrees MT
Am J Surg Pathol 2017 Jun;41(6):788-794. doi: 10.1097/PAS.0000000000000830. PMID: 28296679
Al-Hussain T, Bakshi N, Akhtar M
Adv Anat Pathol 2015 May;22(3):202-12. doi: 10.1097/PAP.0000000000000066. PMID: 25844678
Sesterhenn IA, Davis CJ Jr
Cancer Control 2004 Nov-Dec;11(6):374-87. doi: 10.1177/107327480401100605. PMID: 15625525
Batata MA, Whitmore WF Jr, Chu FC, Hilaris BS, Loh J, Grabstald H, Golbey R
J Urol 1980 Sep;124(3):382-7. doi: 10.1016/s0022-5347(17)55458-0. PMID: 6107388

Diagnosis

Stang A, Rusner C, Trabert B, Oosterhuis JW, McGlynn KA, Heidinger O
Andrology 2019 Jul;7(4):402-407. Epub 2018 Dec 21 doi: 10.1111/andr.12565. PMID: 30578617Free PMC Article
Gondim DD, Ulbright TM, Cheng L, Idrees MT
Am J Surg Pathol 2017 Jun;41(6):788-794. doi: 10.1097/PAS.0000000000000830. PMID: 28296679
Kao CS, Ulbright TM, Young RH, Idrees MT
Am J Surg Pathol 2014 May;38(5):689-97. doi: 10.1097/PAS.0000000000000171. PMID: 24503753
Young RH
Arch Pathol Lab Med 2008 Apr;132(4):548-64. doi: 10.5858/2008-132-548-TTNAAF. PMID: 18384207
Sesterhenn IA, Davis CJ Jr
Cancer Control 2004 Nov-Dec;11(6):374-87. doi: 10.1177/107327480401100605. PMID: 15625525

Therapy

Pagliaro LC
J Clin Oncol 2017 Apr 1;35(10):1036-1040. Epub 2016 Dec 19 doi: 10.1200/JCO.2016.70.6523. PMID: 27992270
Hassan B, Tung K, Weeks R, Mead GM
Cancer 1999 Feb 15;85(4):912-8. PMID: 10091770
Foster BJ, Javadpour N, Ozols RF
Int J Cell Cloning 1983 Apr;1(1):2-14. doi: 10.1002/stem.5530010103. PMID: 6201566
Batata MA, Chu FC, Hilaris BS, Whitmore WF, Golbey RB
Cancer 1982 Mar 1;49(5):1023-30. doi: 10.1002/1097-0142(19820301)49:5<1023::aid-cncr2820490528>3.0.co;2-m. PMID: 6120755
Kaplan JH, Kudish HG, Sacks SA
Postgrad Med 1981 Dec;70(6):125-7, 130-1. doi: 10.1080/00325481.1981.11715938. PMID: 6796949

Prognosis

Wu P, Yang Y, Yu Z, Zhao L, Feng S
J Surg Res 2023 Aug;288:362-371. Epub 2023 Apr 14 doi: 10.1016/j.jss.2023.03.018. PMID: 37062232
Stang A, Trocchi P, Kajüter H, Trabert B, Oosterhuis JW, McGlynn KA
Andrology 2023 Jan;11(1):65-72. Epub 2022 Sep 12 doi: 10.1111/andr.13282. PMID: 36059277
Gondim DD, Ulbright TM, Cheng L, Idrees MT
Am J Surg Pathol 2017 Jun;41(6):788-794. doi: 10.1097/PAS.0000000000000830. PMID: 28296679
Batata MA, Chu FC, Hilaris BS, Whitmore WF, Golbey RB
Cancer 1982 Mar 1;49(5):1023-30. doi: 10.1002/1097-0142(19820301)49:5<1023::aid-cncr2820490528>3.0.co;2-m. PMID: 6120755
Batata MA, Whitmore WF Jr, Chu FC, Hilaris BS, Loh J, Grabstald H, Golbey R
J Urol 1980 Sep;124(3):382-7. doi: 10.1016/s0022-5347(17)55458-0. PMID: 6107388

Clinical prediction guides

Zhou Y, Rothrock A, Murugan P, Li F, Bu L
Exp Mol Pathol 2022 Jun;126:104761. Epub 2022 Apr 4 doi: 10.1016/j.yexmp.2022.104761. PMID: 35390309
Osterballe L, Clasen-Linde E, Cortes D, Engholm G, Hertzum-Larsen R, Reinhardt S, Thorup J
J Pediatr Surg 2017 Apr;52(4):587-592. Epub 2016 Aug 27 doi: 10.1016/j.jpedsurg.2016.08.006. PMID: 27614808
Lau SK, Weiss LM, Chu PG
Am J Clin Pathol 2010 May;133(5):762-6. doi: 10.1309/AJCPIPU1MPTBM2FQ. PMID: 20395523
Woodward PJ, Sohaey R, O'Donoghue MJ, Green DE
Radiographics 2002 Jan-Feb;22(1):189-216. doi: 10.1148/radiographics.22.1.g02ja14189. PMID: 11796908
Batata MA, Chu FC, Hilaris BS, Whitmore WF, Golbey RB
Cancer 1982 Mar 1;49(5):1023-30. doi: 10.1002/1097-0142(19820301)49:5<1023::aid-cncr2820490528>3.0.co;2-m. PMID: 6120755

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