Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Urothelial hyperplasia

MedGen UID:: 234463
•Concept ID:: C1336895
•: Pathologic Function

Synonyms:	Urothelial Hyperplasia; urothelial hyperplasia; urothelium hyperplasia

Monarch Initiative:	MONDO:0024483

Definition

Hyperplasia of the transitional epithelium of the urinary tract. Morphologically it is subdivided into flat and papillary hyperplasia. -- 2003 [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVUrothelial hyperplasia

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Non-Neoplastic Disorder
      - Non-Neoplastic Disorder by Special Category
        Hyperplasia
        Urothelial hyperplasia
        Flat urothelial hyperplasia
        Papillary urothelial hyperplasia

Professional guidelines

PubMed

Value of multicolour fluorescence in situ hybridisation (UroVysion) in the differential diagnosis of flat urothelial lesions.

Schwarz S, Rechenmacher M, Filbeck T, Knuechel R, Blaszyk H, Hartmann A, Brockhoff G
J Clin Pathol 2008 Mar;61(3):272-7. Epub 2007 Aug 10 doi: 10.1136/jcp.2007.049684. PMID: 17693577

See all (1)

Recent clinical studies

Etiology

Urine Cytology Findings in Cases of Pseudocarcinomatous Urothelial Hyperplasia of the Bladder Often Represent a Diagnostic Challenge.

Velez Torres JM, Gonzalez ML, Duarte EM, Zein-Sabatto B, Aron M, Gupta NS, Kerr DA, Netto GJ, Jorda M, Kryvenko ON
Arch Pathol Lab Med 2023 Jun 1;147(6):716-721. doi: 10.5858/arpa.2022-0125-OA. PMID: 36191340

Tumour-like lesions of the urinary bladder.

Samaratunga H, Delahunt B, Yaxley J, Egevad L
Pathology 2021 Jan;53(1):44-55. Epub 2020 Oct 15 doi: 10.1016/j.pathol.2020.08.005. PMID: 33070959

Gene expression and DNA methylation regulation of arsenic in mouse bladder tissues and in human urothelial cells.

Jou YC, Wang SC, Dai YC, Chen SY, Shen CH, Lee YR, Chen LC, Liu YW
Oncol Rep 2019 Sep;42(3):1005-1016. Epub 2019 Jul 16 doi: 10.3892/or.2019.7235. PMID: 31322264 Free PMC Article

Pseudocarcinomatous urothelial hyperplasia of the bladder: clinical findings and followup of 70 patients.

Kryvenko ON, Epstein JI
J Urol 2013 Jun;189(6):2083-6. Epub 2012 Dec 7 doi: 10.1016/j.juro.2012.12.005. PMID: 23228381

Papillary urothelial hyperplasia: relationship to urothelial neoplasms.

Readal N, Epstein JI
Pathology 2010 Jun;42(4):360-3. doi: 10.3109/00313021003767322. PMID: 20438409

See all (20)

Diagnosis

Flat intraurothelial lesions of the urinary bladder-do hyperplasia, dysplasia, and atypia of unknown significance need to exist as diagnostic entities? and how to handle in routine clinical practice.

Paner GP, Smith SC, Hartmann A, Agarwal PK, Compérat E, Amin MB
Mod Pathol 2022 Oct;35(10):1296-1305. Epub 2022 Apr 25 doi: 10.1038/s41379-022-01087-7. PMID: 35468997

Tumour-like lesions of the urinary bladder.

Samaratunga H, Delahunt B, Yaxley J, Egevad L
Pathology 2021 Jan;53(1):44-55. Epub 2020 Oct 15 doi: 10.1016/j.pathol.2020.08.005. PMID: 33070959

Dysplasia and carcinoma in situ of the urinary bladder.

Lopez-Beltran A, Marques RC, Montironi R, Reymundo C, Fonseca J, Cheng L
Anal Quant Cytopathol Histpathol 2015 Feb;37(1):29-38. PMID: 26072632

Urothelial dysplasia of the bladder: diagnostic features and clinical significance.

Lopez-Beltran A, Montironi R, Vidal A, Scarpelli M, Cheng L
Anal Quant Cytopathol Histpathol 2013 Jun;35(3):121-9. PMID: 24344498

Urothelial dysplasia and other flat lesions of the urinary bladder: clinicopathologic and molecular features.

Hodges KB, Lopez-Beltran A, Davidson DD, Montironi R, Cheng L
Hum Pathol 2010 Feb;41(2):155-62. Epub 2009 Sep 16 doi: 10.1016/j.humpath.2009.07.002. PMID: 19762067

See all (23)

Therapy

DNA damage, DNA repair and carcinogenicity: Tobacco smoke versus electronic cigarette aerosol.

Tang MS, Lee HW, Weng MW, Wang HT, Hu Y, Chen LC, Park SH, Chan HW, Xu J, Wu XR, Wang H, Yang R, Galdane K, Jackson K, Chu A, Halzack E
Mutat Res Rev Mutat Res 2022 Jan-Jun;789:108409. Epub 2021 Dec 20 doi: 10.1016/j.mrrev.2021.108409. PMID: 35690412 Free PMC Article

Temporary Covered Metallic Ureteral Stent Placement for Ureteral Strictures following Kidney Transplantation: Experience in 8 Patients.

Cao C, Kim JW, Shin JH, Li M, Hong B, Kim YH, Chu HH
J Vasc Interv Radiol 2020 Nov;31(11):1795-1800. Epub 2020 Sep 19 doi: 10.1016/j.jvir.2020.04.004. PMID: 32962854

Use of Self-Expanding Metallic Ureteral Stents in the Secondary Treatment of Ureteral Stenosis Following Kidney Transplantation.

Xu G, Li X, He Y, Zhao H, Yang W, Xie Q
J Endourol 2015 Oct;29(10):1199-203. Epub 2015 Jul 23 doi: 10.1089/end.2015.0188. PMID: 25879569

Ureteral metal stents: a tale or a tool?

Liatsikos EN, Kagadis GC, Barbalias GA, Siablis D
J Endourol 2005 Oct;19(8):934-9. doi: 10.1089/end.2005.19.934. PMID: 16253054

Urothelial hyperplasia complicating use of metal stents in malignant ureteral obstruction.

Hekimoğlu B, Men S, Pinar A, Ozmen E, Soylu SO, Conkbayir I, Kaderoğlu H, Tüzün M
Eur Radiol 1996;6(5):675-81. doi: 10.1007/BF00187672. PMID: 8934134

See all (9)

Prognosis

Tumour-like lesions of the urinary bladder.

Samaratunga H, Delahunt B, Yaxley J, Egevad L
Pathology 2021 Jan;53(1):44-55. Epub 2020 Oct 15 doi: 10.1016/j.pathol.2020.08.005. PMID: 33070959

Loss of FOXA1 Drives Sexually Dimorphic Changes in Urothelial Differentiation and Is an Independent Predictor of Poor Prognosis in Bladder Cancer.

Reddy OL, Cates JM, Gellert LL, Crist HS, Yang Z, Yamashita H, Taylor JA 3rd, Smith JA Jr, Chang SS, Cookson MS, You C, Barocas DA, Grabowska MM, Ye F, Wu XR, Yi Y, Matusik RJ, Kaestner KH, Clark PE, DeGraff DJ
Am J Pathol 2015 May;185(5):1385-95. doi: 10.1016/j.ajpath.2015.01.014. PMID: 25907831 Free PMC Article

Pseudocarcinomatous urothelial hyperplasia of the bladder: clinical findings and followup of 70 patients.

Kryvenko ON, Epstein JI
J Urol 2013 Jun;189(6):2083-6. Epub 2012 Dec 7 doi: 10.1016/j.juro.2012.12.005. PMID: 23228381

Papillary urothelial hyperplasia: relationship to urothelial neoplasms.

Readal N, Epstein JI
Pathology 2010 Jun;42(4):360-3. doi: 10.3109/00313021003767322. PMID: 20438409

Prognostic significance of atypical papillary urothelial hyperplasia.

Swierczynski SL, Epstein JI
Hum Pathol 2002 May;33(5):512-7. doi: 10.1053/hupa.2002.124031. PMID: 12094376

See all (11)

Clinical prediction guides

Urine Cytology Findings in Cases of Pseudocarcinomatous Urothelial Hyperplasia of the Bladder Often Represent a Diagnostic Challenge.

Gene expression and DNA methylation regulation of arsenic in mouse bladder tissues and in human urothelial cells.

Jou YC, Wang SC, Dai YC, Chen SY, Shen CH, Lee YR, Chen LC, Liu YW
Oncol Rep 2019 Sep;42(3):1005-1016. Epub 2019 Jul 16 doi: 10.3892/or.2019.7235. PMID: 31322264 Free PMC Article

Value of multicolour fluorescence in situ hybridisation (UroVysion) in the differential diagnosis of flat urothelial lesions.

Schwarz S, Rechenmacher M, Filbeck T, Knuechel R, Blaszyk H, Hartmann A, Brockhoff G
J Clin Pathol 2008 Mar;61(3):272-7. Epub 2007 Aug 10 doi: 10.1136/jcp.2007.049684. PMID: 17693577

Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer.

Chow NH, Cairns P, Eisenberger CF, Schoenberg MP, Taylor DC, Epstein JI, Sidransky D
Int J Cancer 2000 Nov 20;89(6):514-8. PMID: 11102896

Two approaches for assessing human safety of disperse blue 1.

Haws LC, Jackson BA, Turnbull D, Dressler WE
Regul Toxicol Pharmacol 1994 Feb;19(1):80-96. doi: 10.1006/rtph.1994.1007. PMID: 8159817

See all (9)

MedGen

National Center for Biotechnology Information

Send to:

Urothelial hyperplasia

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

Related information

Recent activity