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Bile duct adenocarcinoma

MedGen UID:
234585
•Concept ID:
C1370800
•
Neoplastic Process
Synonyms: Bile Duct Adenocarcinoma; bile duct adenocarcinoma
SNOMED CT: Bile duct adenocarcinoma (70179006)
 
Monarch Initiative: MONDO:0003193

Definition

An adenocarcinoma arising from the intrahepatic or extrahepatic bile ducts. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBile duct adenocarcinoma

Professional guidelines

PubMed

The utility of villin and mammaglobin in the differential diagnosis between intrahepatic cholangiocarcinoma and breast cancer.
Yang Z
Appl Immunohistochem Mol Morphol 2015 Jan;23(1):19-25. doi: 10.1097/PAI.0000000000000035. PMID: 25153498

Recent clinical studies

Etiology

Endoscopic sphincterotomy and endoscopic biliary stenting do not affect the sensitivity of transpapillary forceps biopsy for the diagnosis of bile duct adenocarcinoma.
Aoki T, Ohno E, Ishikawa T, Mizutani Y, Iida T, Yamao K, Yamamura T, Furukawa K, Nakamura M, Honda T, Ishigami M, Yatsuya H, Kawashima H
BMC Gastroenterol 2022 Jul 5;22(1):329. doi: 10.1186/s12876-022-02402-x. PMID: 35790908Free PMC Article
Surgical outcomes and prognostic factors of distal common bile duct adenocarcinoma: chronological analysis in a single high-volume institutional experience.
Jung JH, Yoon SJ, Lee OJ, Shin SH, Han IW, Heo JS
BMC Surg 2022 Jul 4;22(1):258. doi: 10.1186/s12893-022-01649-1. PMID: 35787702Free PMC Article
Differentiation grade for extrahepatic bile duct adenocarcinoma: Assessed by diffusion-weighted imaging at 3.0-T MR.
Huang XQ, Shu J, Luo L, Jin ML, Lu XF, Yang SG
Eur J Radiol 2016 Nov;85(11):1980-1986. Epub 2016 Sep 9 doi: 10.1016/j.ejrad.2016.09.004. PMID: 27776649
Review of the investigation and surgical management of resectable ampullary adenocarcinoma.
Askew J, Connor S
HPB (Oxford) 2013 Nov;15(11):829-38. Epub 2013 Jan 10 doi: 10.1111/hpb.12038. PMID: 23458317Free PMC Article
Experience with 647 consecutive tumors of the duodenum, ampulla, head of the pancreas, and distal common bile duct.
Michelassi F, Erroi F, Dawson PJ, Pietrabissa A, Noda S, Handcock M, Block GE
Ann Surg 1989 Oct;210(4):544-54; discussion 554-6. doi: 10.1097/00000658-198910000-00015. PMID: 2679459Free PMC Article

Diagnosis

Endoscopic sphincterotomy and endoscopic biliary stenting do not affect the sensitivity of transpapillary forceps biopsy for the diagnosis of bile duct adenocarcinoma.
Aoki T, Ohno E, Ishikawa T, Mizutani Y, Iida T, Yamao K, Yamamura T, Furukawa K, Nakamura M, Honda T, Ishigami M, Yatsuya H, Kawashima H
BMC Gastroenterol 2022 Jul 5;22(1):329. doi: 10.1186/s12876-022-02402-x. PMID: 35790908Free PMC Article
Genome-Derived Classification Signature for Ampullary Adenocarcinoma to Improve Clinical Cancer Care.
Chakraborty S, Ecker BL, Seier K, Aveson VG, Balachandran VP, Drebin JA, D'Angelica MI, Kingham TP, Sigel CS, Soares KC, Vakiani E, Wei AC, Chandwani R, Gonen M, Shen R, Jarnagin WR
Clin Cancer Res 2021 Nov 1;27(21):5891-5899. Epub 2021 Aug 25 doi: 10.1158/1078-0432.CCR-21-1906. PMID: 34433650Free PMC Article
Differentiation grade for extrahepatic bile duct adenocarcinoma: Assessed by diffusion-weighted imaging at 3.0-T MR.
Huang XQ, Shu J, Luo L, Jin ML, Lu XF, Yang SG
Eur J Radiol 2016 Nov;85(11):1980-1986. Epub 2016 Sep 9 doi: 10.1016/j.ejrad.2016.09.004. PMID: 27776649
Review of the investigation and surgical management of resectable ampullary adenocarcinoma.
Askew J, Connor S
HPB (Oxford) 2013 Nov;15(11):829-38. Epub 2013 Jan 10 doi: 10.1111/hpb.12038. PMID: 23458317Free PMC Article
Cholangioscopic findings in bile duct tumors.
Seo DW, Lee SK, Yoo KS, Kang GH, Kim MH, Suh DJ, Min YI
Gastrointest Endosc 2000 Nov;52(5):630-4. doi: 10.1067/mge.2000.108667. PMID: 11060187

Therapy

Endoscopic sphincterotomy and endoscopic biliary stenting do not affect the sensitivity of transpapillary forceps biopsy for the diagnosis of bile duct adenocarcinoma.
Aoki T, Ohno E, Ishikawa T, Mizutani Y, Iida T, Yamao K, Yamamura T, Furukawa K, Nakamura M, Honda T, Ishigami M, Yatsuya H, Kawashima H
BMC Gastroenterol 2022 Jul 5;22(1):329. doi: 10.1186/s12876-022-02402-x. PMID: 35790908Free PMC Article
New staining method using methionyl-tRNA synthetase 1 antibody for brushing cytology of bile duct cancer.
Jang SI, Kwon NH, Lim BJ, Nahm JH, Park JS, Kang CM, Park SR, Lee Sd SY, Kang BS, Kim S, Lee DK
Gastrointest Endosc 2020 Aug;92(2):310-319.e6. Epub 2019 Dec 24 doi: 10.1016/j.gie.2019.12.017. PMID: 31874158
Analysis of intrahepatic sarcomatoid cholangiocarcinoma: Experience from 11 cases within 17 years.
Kim DK, Kim BR, Jeong JS, Baek YH
World J Gastroenterol 2019 Feb 7;25(5):608-621. doi: 10.3748/wjg.v25.i5.608. PMID: 30774275Free PMC Article
Extrahepatic bile duct adenocarcinoma: patients at high-risk for local recurrence treated with surgery and adjuvant chemoradiation have an equivalent overall survival to patients with standard-risk treated with surgery alone.
Borghero Y, Crane CH, Szklaruk J, Oyarzo M, Curley S, Pisters PW, Evans D, Abdalla EK, Thomas MB, Das P, Wistuba II, Krishnan S, Vauthey JN
Ann Surg Oncol 2008 Nov;15(11):3147-56. Epub 2008 Aug 27 doi: 10.1245/s10434-008-9998-7. PMID: 18754070
Radiochemotherapy followed by gemcitabine and capecitabine in extrahepatic bile duct cancer: a phase I/II trial.
Schoppmeyer K, Miethe S, Wiedmann M, Liebmann A, Hauss J, Mossner J, Caca K, Witzigmann H, Hildebrandt G
Am J Clin Oncol 2006 Dec;29(6):576-82. doi: 10.1097/01.coc.0000239167.17922.82. PMID: 17148994

Prognosis

Surgical outcomes and prognostic factors of distal common bile duct adenocarcinoma: chronological analysis in a single high-volume institutional experience.
Jung JH, Yoon SJ, Lee OJ, Shin SH, Han IW, Heo JS
BMC Surg 2022 Jul 4;22(1):258. doi: 10.1186/s12893-022-01649-1. PMID: 35787702Free PMC Article
Genome-Derived Classification Signature for Ampullary Adenocarcinoma to Improve Clinical Cancer Care.
Chakraborty S, Ecker BL, Seier K, Aveson VG, Balachandran VP, Drebin JA, D'Angelica MI, Kingham TP, Sigel CS, Soares KC, Vakiani E, Wei AC, Chandwani R, Gonen M, Shen R, Jarnagin WR
Clin Cancer Res 2021 Nov 1;27(21):5891-5899. Epub 2021 Aug 25 doi: 10.1158/1078-0432.CCR-21-1906. PMID: 34433650Free PMC Article
Differentiation grade for extrahepatic bile duct adenocarcinoma: Assessed by diffusion-weighted imaging at 3.0-T MR.
Huang XQ, Shu J, Luo L, Jin ML, Lu XF, Yang SG
Eur J Radiol 2016 Nov;85(11):1980-1986. Epub 2016 Sep 9 doi: 10.1016/j.ejrad.2016.09.004. PMID: 27776649
Review of the investigation and surgical management of resectable ampullary adenocarcinoma.
Askew J, Connor S
HPB (Oxford) 2013 Nov;15(11):829-38. Epub 2013 Jan 10 doi: 10.1111/hpb.12038. PMID: 23458317Free PMC Article
Intracellular localization of mesothelin predicts patient prognosis of extrahepatic bile duct cancer.
Kawamata F, Kamachi H, Einama T, Homma S, Tahara M, Miyazaki M, Tanaka S, Kamiyama T, Nishihara H, Taketomi A, Todo S
Int J Oncol 2012 Dec;41(6):2109-18. Epub 2012 Oct 15 doi: 10.3892/ijo.2012.1662. PMID: 23064529

Clinical prediction guides

Surgical outcomes and prognostic factors of distal common bile duct adenocarcinoma: chronological analysis in a single high-volume institutional experience.
Jung JH, Yoon SJ, Lee OJ, Shin SH, Han IW, Heo JS
BMC Surg 2022 Jul 4;22(1):258. doi: 10.1186/s12893-022-01649-1. PMID: 35787702Free PMC Article
Genome-Derived Classification Signature for Ampullary Adenocarcinoma to Improve Clinical Cancer Care.
Chakraborty S, Ecker BL, Seier K, Aveson VG, Balachandran VP, Drebin JA, D'Angelica MI, Kingham TP, Sigel CS, Soares KC, Vakiani E, Wei AC, Chandwani R, Gonen M, Shen R, Jarnagin WR
Clin Cancer Res 2021 Nov 1;27(21):5891-5899. Epub 2021 Aug 25 doi: 10.1158/1078-0432.CCR-21-1906. PMID: 34433650Free PMC Article
Analysis of intrahepatic sarcomatoid cholangiocarcinoma: Experience from 11 cases within 17 years.
Kim DK, Kim BR, Jeong JS, Baek YH
World J Gastroenterol 2019 Feb 7;25(5):608-621. doi: 10.3748/wjg.v25.i5.608. PMID: 30774275Free PMC Article
Differentiation grade for extrahepatic bile duct adenocarcinoma: Assessed by diffusion-weighted imaging at 3.0-T MR.
Huang XQ, Shu J, Luo L, Jin ML, Lu XF, Yang SG
Eur J Radiol 2016 Nov;85(11):1980-1986. Epub 2016 Sep 9 doi: 10.1016/j.ejrad.2016.09.004. PMID: 27776649
Radiochemotherapy followed by gemcitabine and capecitabine in extrahepatic bile duct cancer: a phase I/II trial.
Schoppmeyer K, Miethe S, Wiedmann M, Liebmann A, Hauss J, Mossner J, Caca K, Witzigmann H, Hildebrandt G
Am J Clin Oncol 2006 Dec;29(6):576-82. doi: 10.1097/01.coc.0000239167.17922.82. PMID: 17148994

Recent systematic reviews

Review of the investigation and surgical management of resectable ampullary adenocarcinoma.
Askew J, Connor S
HPB (Oxford) 2013 Nov;15(11):829-38. Epub 2013 Jan 10 doi: 10.1111/hpb.12038. PMID: 23458317Free PMC Article

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