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Thymic sarcomatoid carcinoma

MedGen UID:
234772
•Concept ID:
C1335924
•
Neoplastic Process
Synonyms: Sarcomatoid Carcinoma of the Thymus; sarcomatoid carcinoma of the Thymus; Sarcomatoid Carcinoma of Thymus; sarcomatoid carcinoma of Thymus; Thymic Carcinosarcoma; thymic carcinosarcoma; Thymic Sarcomatoid Carcinoma; thymic sarcomatoid carcinoma; Thymic Spindle Cell Carcinoma; thymic spindle cell carcinoma; Thymus Sarcomatoid Carcinoma; Thymus sarcomatoid carcinoma; thymus sarcomatoid carcinoma
 
Monarch Initiative: MONDO:0006452

Definition

A rare, usually aggressive, primary thymic carcinoma, characterized by the presence of tumor cells morphologically resembling soft tissue sarcoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThymic sarcomatoid carcinoma

Professional guidelines

PubMed

Treatment of Oligometastatic Non-Small Cell Lung Cancer: An ASTRO/ESTRO Clinical Practice Guideline.
Iyengar P, All S, Berry MF, Boike TP, Bradfield L, Dingemans AC, Feldman J, Gomez DR, Hesketh PJ, Jabbour SK, Jeter M, Josipovic M, Lievens Y, McDonald F, Perez BA, Ricardi U, Ruffini E, De Ruysscher D, Saeed H, Schneider BJ, Senan S, Widder J, Guckenberger M
Pract Radiat Oncol 2023 Sep-Oct;13(5):393-412. Epub 2023 Apr 25 doi: 10.1016/j.prro.2023.04.004. PMID: 37294262
Chinese expert consensus on the diagnosis and treatment of thymic epithelial tumors.
Xu C, Zhang Y, Wang W, Wang Q, Li Z, Song Z, Wang J, Yu J, Liu J, Zhang S, Cai X, Wu M, Zhan P, Liu H, Lv T, Miao L, Min L, Li J, Liu B, Yuan J, Jiang Z, Lin G, Chen X, Pu X, Rao C, Lv D, Yu Z, Li X, Tang C, Zhou C, Zhang J, Guo H, Chu Q, Meng R, Liu X, Wu J, Hu X, Fang M, Zhou J, Zhu Z, Chen X, Pan W, Pang F, Zhou Y, Jian Q, Wang K, Wang L, Zhu Y, Yang G, Lin X, Cai J, Liang L, Feng H, Wang L, Du Y, Yao W, Shi X, Niu X, Yuan D, Yao Y, Huang J, Zhang Y, Sun P, Wang H, Ye M, Wang D, Wang Z, Hao Y, Wang Z, Wan B, Lv D, Yu G, Li A, Kang J, Zhang J, Zhang C, Chen H, Shi L, Ye L, Wang G, Wang Y, Gao F, Zhou W, Hu C, Wei J, Li B, Li Z, Li Y, Liu Z, Yang N, Wu L, Wang Q, Huang W, Hong Z, Wang G, Fang M, Fang Y, Zhu X, Du K, Ji J, Shen Y, Zhang Y, Ma S, Song Y, Lu Y, Liu A, Fang W, Zhong W
Thorac Cancer 2023 Apr;14(12):1102-1117. Epub 2023 Mar 16 doi: 10.1111/1759-7714.14847. PMID: 36924056Free PMC Article
Lung and thymic carcinoids: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up(☆).
Baudin E, Caplin M, Garcia-Carbonero R, Fazio N, Ferolla P, Filosso PL, Frilling A, de Herder WW, Hörsch D, Knigge U, Korse CM, Lim E, Lombard-Bohas C, Pavel M, Scoazec JY, Sundin A, Berruti A; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2021 Apr;32(4):439-451. Epub 2021 Jan 19 doi: 10.1016/j.annonc.2021.01.003. PMID: 33482246

Recent clinical studies

Diagnosis

Malignant Transformation of Metaplastic Thymoma into High-Grade Sarcomatoid Carcinoma: A Case Report.
Piao ZH, Chen JP, Chen HR, Zhou XC
Int J Surg Pathol 2022 Aug;30(5):564-568. Epub 2021 Dec 31 doi: 10.1177/10668969211070484. PMID: 34970930
Four cases of invasive anterior mediastinal tumors definitively diagnosed by the chamberlain procedure.
Shimizu J, Kamesui T, Moriya M, Murata S, Nakanishi I, Sasaki M, Minato H
Ann Thorac Cardiovasc Surg 2014;20 Suppl:434-40. Epub 2013 Apr 11 doi: 10.5761/atcs.cr.12.02185. PMID: 23574996

Prognosis

Four cases of invasive anterior mediastinal tumors definitively diagnosed by the chamberlain procedure.
Shimizu J, Kamesui T, Moriya M, Murata S, Nakanishi I, Sasaki M, Minato H
Ann Thorac Cardiovasc Surg 2014;20 Suppl:434-40. Epub 2013 Apr 11 doi: 10.5761/atcs.cr.12.02185. PMID: 23574996
Thymic sarcomatoid carcinoma with skeletal muscle differentiation: report of two cases, one with cytogenetic analysis.
Eimoto T, Kitaoka M, Ogawa H, Niwa H, Murase T, Tateyama H, Inagaki H, Soji T, Wang HJ
Histopathology 2002 Jan;40(1):46-57. doi: 10.1046/j.1365-2559.2002.01310.x. PMID: 11903597

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