Stage IIB includes: (T2-3, N0, M0, G2-3, Tumor location: Upper, middle); (T1-2, N1, M0, Any G, Tumor location: Any). T2: Tumor invades muscularis propria. T3: Tumor invades adventitia. T1: Tumor invades lamina propria, muscularis mucosae, or submucosa. N0: No regional lymph node metastasis. N1: Metastasis in 1-2 regional lymph nodes. M0: No distant metastasis. G2: Moderately differentiated. G3: Poorly differentiated. Tumor location: Location of the primary cancer site is defined by the position of the upper (proximal) edge of the tumor in the esophagus. (AJCC 7th ed.) [from
NCI]