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Vaginal yolk sac tumor

MedGen UID:
234985
•Concept ID:
C1336945
•
Neoplastic Process
Synonyms: Vaginal Endodermal Sinus Neoplasm; vaginal endodermal sinus neoplasm; Vaginal Endodermal Sinus Tumor; vaginal endodermal sinus tumor; vaginal endodermal sinus tumour; Vaginal Yolk Sac Neoplasm; vaginal yolk Sac neoplasm; Vaginal Yolk Sac Tumor; vaginal yolk sac tumor; vaginal yolk Sac tumor; vaginal yolk Sac tumour; yolk sac tumor; yolk sac tumour
 
Monarch Initiative: MONDO:0002143

Definition

A rare yolk sac tumor that arises from the vagina. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVaginal yolk sac tumor

Professional guidelines

PubMed

Pediatric Vaginal Yolk Sac Tumor: Reappraisal of Treatment Strategy in a Rare Tumor at a Unique Location.
Rajagopal R, Ariffin H, Krishnan S, Abdullah WA, Lin HP
J Pediatr Hematol Oncol 2015 Jul;37(5):391-5. doi: 10.1097/MPH.0000000000000344. PMID: 25929614

Recent clinical studies

Etiology

Vaginal Yolk Sac Tumor: A Case Series and Review of the Literature.
Mayhew AC, Rytting H, Olson TA, Smith E, Childress KJ
J Pediatr Adolesc Gynecol 2021 Feb;34(1):54-60.e4. Epub 2020 Jul 3 doi: 10.1016/j.jpag.2020.06.020. PMID: 32628992
Endoscopic surgery combining chemotherapy for vaginal yolk-sac tumor: a case report.
Fang X, Du W, Wang Q, Zhao X
Eur J Gynaecol Oncol 2015;36(3):335-8. PMID: 26189265
Pediatric Vaginal Yolk Sac Tumor: Reappraisal of Treatment Strategy in a Rare Tumor at a Unique Location.
Rajagopal R, Ariffin H, Krishnan S, Abdullah WA, Lin HP
J Pediatr Hematol Oncol 2015 Jul;37(5):391-5. doi: 10.1097/MPH.0000000000000344. PMID: 25929614

Diagnosis

Vaginal Yolk Sac Tumor: A Case Series and Review of the Literature.
Mayhew AC, Rytting H, Olson TA, Smith E, Childress KJ
J Pediatr Adolesc Gynecol 2021 Feb;34(1):54-60.e4. Epub 2020 Jul 3 doi: 10.1016/j.jpag.2020.06.020. PMID: 32628992
A Rare Case of Pediatric Vaginal Yolk Sac Tumor.
Lightfoot MA, Bilgutay AN, Kirsch AJ
Urology 2018 Sep;119:137-139. Epub 2018 Mar 13 doi: 10.1016/j.urology.2018.01.007. PMID: 29548872
Vaginal Yolk Sac Tumor in an Infant.
Waqas M, Malik SN, Shohab D, Tariq N, Hussain I, Iqbal Y
J Coll Physicians Surg Pak 2017 Sep;27(9):S112-S113. PMID: 28969744
Prognosis of eight Chinese cases of primary vaginal yolk sac tumor with a review of the literature.
Tang QL, Jiang XF, Yuan XP, Liu Y, Zhang L, Tang XF, Zhou JJ, Li HG, Fang JP, Xue L
Asian Pac J Cancer Prev 2014;15(21):9395-404. doi: 10.7314/apjcp.2014.15.21.9395. PMID: 25422231
Vaginal yolk sac tumor causing infantile hydrometra: use of multidetector-row computed tomography.
Wani NA, Robbani I, Andrabi AH, Iqbal A, Qayum A
J Pediatr Adolesc Gynecol 2010 Jun;23(3):e115-8. Epub 2009 Dec 5 doi: 10.1016/j.jpag.2009.10.005. PMID: 19963410

Therapy

Vaginal Yolk Sac Tumor in an Infant.
Waqas M, Malik SN, Shohab D, Tariq N, Hussain I, Iqbal Y
J Coll Physicians Surg Pak 2017 Sep;27(9):S112-S113. PMID: 28969744
Endoscopic surgery combining chemotherapy for vaginal yolk-sac tumor: a case report.
Fang X, Du W, Wang Q, Zhao X
Eur J Gynaecol Oncol 2015;36(3):335-8. PMID: 26189265
Pediatric Vaginal Yolk Sac Tumor: Reappraisal of Treatment Strategy in a Rare Tumor at a Unique Location.
Rajagopal R, Ariffin H, Krishnan S, Abdullah WA, Lin HP
J Pediatr Hematol Oncol 2015 Jul;37(5):391-5. doi: 10.1097/MPH.0000000000000344. PMID: 25929614

Prognosis

A Rare Case of Pediatric Vaginal Yolk Sac Tumor.
Lightfoot MA, Bilgutay AN, Kirsch AJ
Urology 2018 Sep;119:137-139. Epub 2018 Mar 13 doi: 10.1016/j.urology.2018.01.007. PMID: 29548872
Pediatric Vaginal Yolk Sac Tumor: Reappraisal of Treatment Strategy in a Rare Tumor at a Unique Location.
Rajagopal R, Ariffin H, Krishnan S, Abdullah WA, Lin HP
J Pediatr Hematol Oncol 2015 Jul;37(5):391-5. doi: 10.1097/MPH.0000000000000344. PMID: 25929614
Prognosis of eight Chinese cases of primary vaginal yolk sac tumor with a review of the literature.
Tang QL, Jiang XF, Yuan XP, Liu Y, Zhang L, Tang XF, Zhou JJ, Li HG, Fang JP, Xue L
Asian Pac J Cancer Prev 2014;15(21):9395-404. doi: 10.7314/apjcp.2014.15.21.9395. PMID: 25422231

Clinical prediction guides

Vaginal yolk sac tumor in a nine-month-old female child.
Catipović M, Crnojević-Ivanusić R, Dujsin M, Batinica S, Cacić M, Markoja I
Croat Med J 1998 Mar;39(1):66-8. PMID: 9475811

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