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Kaposi Sarcoma NCI Grade 3

MedGen UID:
235241
Concept ID:
C1334321
Neoplastic Process
Synonyms: Kaposi's Sarcoma NCI Grade 3; Kaposi's Sarcoma NCI Grade III

Definition

A Kaposi sarcoma with more than 15% necrosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVKaposi Sarcoma NCI Grade 3

Recent clinical studies

Etiology

Ramaswami R, Polizzotto MN, Lurain K, Wyvill KM, Widell A, George J, Goncalves P, Steinberg SM, Whitby D, Uldrick TS, Yarchoan R
Clin Cancer Res 2022 Mar 1;28(5):840-850. doi: 10.1158/1078-0432.CCR-21-3364. PMID: 34862247Free PMC Article
Lurain K, Ramaswami R, Mangusan R, Widell A, Ekwede I, George J, Ambinder R, Cheever M, Gulley JL, Goncalves PH, Wang HW, Uldrick TS, Yarchoan R
J Immunother Cancer 2021 Feb;9(2) doi: 10.1136/jitc-2020-002097. PMID: 33608378Free PMC Article
Polizzotto MN, Uldrick TS, Wyvill KM, Aleman K, Marshall V, Wang V, Whitby D, Pittaluga S, Jaffe ES, Millo C, Tosato G, Little RF, Steinberg SM, Sereti I, Yarchoan R
Clin Infect Dis 2016 Mar 15;62(6):730-738. Epub 2015 Dec 12 doi: 10.1093/cid/civ996. PMID: 26658701Free PMC Article
Herce ME, Kalanga N, Wroe EB, Keck JW, Chingoli F, Tengatenga L, Gopal S, Phiri A, Mailosi B, Bazile J, Beste JA, Elmore SN, Crocker JT, Rigodon J
J Int AIDS Soc 2015;18(1):19929. Epub 2015 May 29 doi: 10.7448/IAS.18.1.19929. PMID: 26028156Free PMC Article
Ziegler JL, Bragg K, Abrams D, Beckstead J, Cogan M, Volberding P, Baer D, Wilkinson L, Rosenbaum E, Grant K
Ann N Y Acad Sci 1984;437:412-9. doi: 10.1111/j.1749-6632.1984.tb37161.x. PMID: 6598309

Diagnosis

Polizzotto MN, Uldrick TS, Wyvill KM, Aleman K, Marshall V, Wang V, Whitby D, Pittaluga S, Jaffe ES, Millo C, Tosato G, Little RF, Steinberg SM, Sereti I, Yarchoan R
Clin Infect Dis 2016 Mar 15;62(6):730-738. Epub 2015 Dec 12 doi: 10.1093/cid/civ996. PMID: 26658701Free PMC Article
Uldrick TS, Wyvill KM, Kumar P, O'Mahony D, Bernstein W, Aleman K, Polizzotto MN, Steinberg SM, Pittaluga S, Marshall V, Whitby D, Little RF, Yarchoan R
J Clin Oncol 2012 May 1;30(13):1476-83. Epub 2012 Mar 19 doi: 10.1200/JCO.2011.39.6853. PMID: 22430271Free PMC Article
Sprinz E, Caldas AP, Mans DR, Cancela A, DiLeone L, Dalla Costa T, Schwartsmann G
Am J Clin Oncol 2001 Apr;24(2):177-84. doi: 10.1097/00000421-200104000-00016. PMID: 11319295
Ragni MV, Belle SH, Jaffe RA, Duerstein SL, Bass DC, McMillan CW, Lovrien EW, Aledort LM, Kisker CT, Stabler SP
Blood 1993 Apr 1;81(7):1889-97. PMID: 8461474
Ziegler JL, Bragg K, Abrams D, Beckstead J, Cogan M, Volberding P, Baer D, Wilkinson L, Rosenbaum E, Grant K
Ann N Y Acad Sci 1984;437:412-9. doi: 10.1111/j.1749-6632.1984.tb37161.x. PMID: 6598309

Therapy

Ramaswami R, Polizzotto MN, Lurain K, Wyvill KM, Widell A, George J, Goncalves P, Steinberg SM, Whitby D, Uldrick TS, Yarchoan R
Clin Cancer Res 2022 Mar 1;28(5):840-850. doi: 10.1158/1078-0432.CCR-21-3364. PMID: 34862247Free PMC Article
Lurain K, Ramaswami R, Mangusan R, Widell A, Ekwede I, George J, Ambinder R, Cheever M, Gulley JL, Goncalves PH, Wang HW, Uldrick TS, Yarchoan R
J Immunother Cancer 2021 Feb;9(2) doi: 10.1136/jitc-2020-002097. PMID: 33608378Free PMC Article
Polizzotto MN, Uldrick TS, Wyvill KM, Aleman K, Peer CJ, Bevans M, Sereti I, Maldarelli F, Whitby D, Marshall V, Goncalves PH, Khetani V, Figg WD, Steinberg SM, Zeldis JB, Yarchoan R
J Clin Oncol 2016 Dec;34(34):4125-4131. Epub 2016 Oct 31 doi: 10.1200/JCO.2016.69.3812. PMID: 27863194Free PMC Article
Polizzotto MN, Uldrick TS, Wyvill KM, Aleman K, Marshall V, Wang V, Whitby D, Pittaluga S, Jaffe ES, Millo C, Tosato G, Little RF, Steinberg SM, Sereti I, Yarchoan R
Clin Infect Dis 2016 Mar 15;62(6):730-738. Epub 2015 Dec 12 doi: 10.1093/cid/civ996. PMID: 26658701Free PMC Article
Herce ME, Kalanga N, Wroe EB, Keck JW, Chingoli F, Tengatenga L, Gopal S, Phiri A, Mailosi B, Bazile J, Beste JA, Elmore SN, Crocker JT, Rigodon J
J Int AIDS Soc 2015;18(1):19929. Epub 2015 May 29 doi: 10.7448/IAS.18.1.19929. PMID: 26028156Free PMC Article

Prognosis

Ramaswami R, Polizzotto MN, Lurain K, Wyvill KM, Widell A, George J, Goncalves P, Steinberg SM, Whitby D, Uldrick TS, Yarchoan R
Clin Cancer Res 2022 Mar 1;28(5):840-850. doi: 10.1158/1078-0432.CCR-21-3364. PMID: 34862247Free PMC Article
Uldrick TS, Gonçalves PH, Wyvill KM, Peer CJ, Bernstein W, Aleman K, Polizzotto MN, Venzon D, Steinberg SM, Marshall V, Whitby D, Little RF, Wright JJ, Rudek MA, Figg WD, Yarchoan R
Oncologist 2017 May;22(5):505-e49. Epub 2017 Mar 24 doi: 10.1634/theoncologist.2016-0486. PMID: 28341759Free PMC Article
Brinker BT, Krown SE, Lee JY, Cesarman E, Chadburn A, Kaplan LD, Henry DH, Von Roenn JH
Cancer 2008 Mar 1;112(5):1083-8. doi: 10.1002/cncr.23108. PMID: 18224669
Sprinz E, Caldas AP, Mans DR, Cancela A, DiLeone L, Dalla Costa T, Schwartsmann G
Am J Clin Oncol 2001 Apr;24(2):177-84. doi: 10.1097/00000421-200104000-00016. PMID: 11319295
Ziegler JL, Bragg K, Abrams D, Beckstead J, Cogan M, Volberding P, Baer D, Wilkinson L, Rosenbaum E, Grant K
Ann N Y Acad Sci 1984;437:412-9. doi: 10.1111/j.1749-6632.1984.tb37161.x. PMID: 6598309

Clinical prediction guides

Uldrick TS, Gonçalves PH, Wyvill KM, Peer CJ, Bernstein W, Aleman K, Polizzotto MN, Venzon D, Steinberg SM, Marshall V, Whitby D, Little RF, Wright JJ, Rudek MA, Figg WD, Yarchoan R
Oncologist 2017 May;22(5):505-e49. Epub 2017 Mar 24 doi: 10.1634/theoncologist.2016-0486. PMID: 28341759Free PMC Article
Uldrick TS, Wyvill KM, Kumar P, O'Mahony D, Bernstein W, Aleman K, Polizzotto MN, Steinberg SM, Pittaluga S, Marshall V, Whitby D, Little RF, Yarchoan R
J Clin Oncol 2012 May 1;30(13):1476-83. Epub 2012 Mar 19 doi: 10.1200/JCO.2011.39.6853. PMID: 22430271Free PMC Article
Brinker BT, Krown SE, Lee JY, Cesarman E, Chadburn A, Kaplan LD, Henry DH, Von Roenn JH
Cancer 2008 Mar 1;112(5):1083-8. doi: 10.1002/cncr.23108. PMID: 18224669
Takebe N, Paredes J, Pino MC, Lownsbury WH, Agosti J, Krown SE
J Interferon Cytokine Res 1998 May;18(5):321-6. doi: 10.1089/jir.1998.18.321. PMID: 9620359
Ragni MV, Belle SH, Jaffe RA, Duerstein SL, Bass DC, McMillan CW, Lovrien EW, Aledort LM, Kisker CT, Stabler SP
Blood 1993 Apr 1;81(7):1889-97. PMID: 8461474

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