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Sclerosing Pneumocytoma

MedGen UID:
235268
Concept ID:
C1334455
Neoplastic Process
Synonyms: Hemangioma, Sclerosing, Pulmonary; Lung Sclerosing Hemangioma; Lung Sclerosing Hemangiomas; Pulmonary Sclerosing Hemangioma; Pulmonary Sclerosing Hemangiomas; Sclerosing Hemangioma of the Lung; Sclerosing Hemangioma, Lung; Sclerosing Hemangioma, Pulmonary; Sclerosing Hemangiomas, Lung; Sclerosing Hemangiomas, Pulmonary
SNOMED CT: Pulmonary sclerosing hemangioma (707365008); Sclerosing hemangioma of lung (707365008); Sclerosing pneumocytoma (725967000)

Definition

A benign tumor that arises from the lung. It is characterized by the presence of sclerotic, papillary, solid, and hemorrhagic patterns and hyperplastic type II pneumocytes. Cholesterol clefts, hemosiderin deposition, chronic inflammation, and calcifications may be present. In the majority of cases, it is a solitary and peripheral tumor. Patients are usually asymptomatic. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSclerosing Pneumocytoma

Professional guidelines

Recent clinical studies

Etiology

Kim SJ, Kang HR, Lee CG, Choi SH, Kim YW, Lee HW, Lee CH
BMC Pulm Med 2022 Nov 7;22(1):404. doi: 10.1186/s12890-022-02199-1. PMID: 36344955Free PMC Article
Zheng Q, Zhou J, Li G, Man S, Lin Z, Wang T, Chen B, Lin F
World J Surg Oncol 2022 Apr 30;20(1):140. doi: 10.1186/s12957-022-02603-4. PMID: 35490241Free PMC Article
Boland JM, Lee HE, Barr Fritcher EG, Voss JS, Jessen E, Davila JI, Kipp BR, Graham RP, Maleszewski JJ, Yi ES
Am J Clin Pathol 2021 Feb 11;155(3):397-404. doi: 10.1093/ajcp/aqaa136. PMID: 33145590
Lovrenski A, Vasilijević M, Panjković M, Tegeltija D, Vučković D, Baroš I, Lovrenski J
Medicina (Kaunas) 2019 Jan 25;55(2) doi: 10.3390/medicina55020027. PMID: 30691016Free PMC Article
Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JHM, Beasley MB, Chirieac LR, Dacic S, Duhig E, Flieder DB, Geisinger K, Hirsch FR, Ishikawa Y, Kerr KM, Noguchi M, Pelosi G, Powell CA, Tsao MS, Wistuba I; WHO Panel
J Thorac Oncol 2015 Sep;10(9):1243-1260. doi: 10.1097/JTO.0000000000000630. PMID: 26291008

Diagnosis

Kim SJ, Kang HR, Lee CG, Choi SH, Kim YW, Lee HW, Lee CH
BMC Pulm Med 2022 Nov 7;22(1):404. doi: 10.1186/s12890-022-02199-1. PMID: 36344955Free PMC Article
Boland JM
Mod Pathol 2022 Jan;35(Suppl 1):57-65. Epub 2021 Sep 13 doi: 10.1038/s41379-021-00914-7. PMID: 34518633
Pal P, Chetty R
J Clin Pathol 2020 Sep;73(9):531-534. Epub 2020 Apr 21 doi: 10.1136/jclinpath-2020-206501. PMID: 32317291
Maleki Z, Muller S, Layfield L, Siddiqui MT, Rekhtman N, Pantanowitz L
Cancer Cytopathol 2020 Jun;128(6):414-423. Epub 2020 Feb 5 doi: 10.1002/cncy.22251. PMID: 32022435Free PMC Article
Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JHM, Beasley MB, Chirieac LR, Dacic S, Duhig E, Flieder DB, Geisinger K, Hirsch FR, Ishikawa Y, Kerr KM, Noguchi M, Pelosi G, Powell CA, Tsao MS, Wistuba I; WHO Panel
J Thorac Oncol 2015 Sep;10(9):1243-1260. doi: 10.1097/JTO.0000000000000630. PMID: 26291008

Therapy

Kim SJ, Kang HR, Lee CG, Choi SH, Kim YW, Lee HW, Lee CH
BMC Pulm Med 2022 Nov 7;22(1):404. doi: 10.1186/s12890-022-02199-1. PMID: 36344955Free PMC Article
Luo C, Song Y, Liu Y, Wang R, Gao J, Yue S, Ding C
BMC Med Imaging 2022 Feb 2;22(1):16. doi: 10.1186/s12880-022-00745-1. PMID: 35105314Free PMC Article
Liu H, Dang H, Wang R, Yao S, Wu Y, Xu B
Nucl Med Commun 2021 Jun 1;42(6):665-671. doi: 10.1097/MNM.0000000000001374. PMID: 33660695
Xu J, Dong Y, Yin G, Jiang W, Yang Z, Xu W, Zhu L
Thorac Cancer 2019 Jul;10(7):1552-1560. Epub 2019 May 27 doi: 10.1111/1759-7714.13100. PMID: 31131992Free PMC Article

Prognosis

Zheng Q, Zhou J, Li G, Man S, Lin Z, Wang T, Chen B, Lin F
World J Surg Oncol 2022 Apr 30;20(1):140. doi: 10.1186/s12957-022-02603-4. PMID: 35490241Free PMC Article
Luo C, Song Y, Liu Y, Wang R, Gao J, Yue S, Ding C
BMC Med Imaging 2022 Feb 2;22(1):16. doi: 10.1186/s12880-022-00745-1. PMID: 35105314Free PMC Article
Boland JM
Mod Pathol 2022 Jan;35(Suppl 1):57-65. Epub 2021 Sep 13 doi: 10.1038/s41379-021-00914-7. PMID: 34518633
Wang Z, Yang MQ, Huang WJ, Zhang D, Xu HT
Medicine (Baltimore) 2019 Feb;98(5):e14315. doi: 10.1097/MD.0000000000014315. PMID: 30702609Free PMC Article
Wu CY, Wang J, Chang NY
Int J Surg Pathol 2016 Oct;24(7):600-6. Epub 2016 May 8 doi: 10.1177/1066896916648448. PMID: 27160435

Clinical prediction guides

Saripalli KR, Wang MQW, Chow CY, Chew SY
BMJ Case Rep 2023 Nov 17;16(11) doi: 10.1136/bcr-2023-257208. PMID: 37977835Free PMC Article
Kim SJ, Kang HR, Lee CG, Choi SH, Kim YW, Lee HW, Lee CH
BMC Pulm Med 2022 Nov 7;22(1):404. doi: 10.1186/s12890-022-02199-1. PMID: 36344955Free PMC Article
Toro Soto PA, Rivero de Jesús É, Arenas Jiménez J, Aranda López FI
Rev Esp Patol 2022 Sep;55 Suppl 1:S44-S48. Epub 2020 May 6 doi: 10.1016/j.patol.2020.02.009. PMID: 36075662
Yeh YC, Ho HL, Wu YC, Pan CC, Wang YC, Chou TY
Mod Pathol 2020 Mar;33(3):391-403. Epub 2019 Sep 16 doi: 10.1038/s41379-019-0357-y. PMID: 31527710
Wang X, Zhang L, Wang Y, Jia X, Wang J, Zhang H
Indian J Pathol Microbiol 2018 Jul-Sep;61(3):407-409. doi: 10.4103/IJPM.IJPM_98_17. PMID: 30004067

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