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Meningothelial Cell Neoplasm

MedGen UID:
235318
•Concept ID:
C1334698
•
Neoplastic Process
Synonyms: Meningothelial Cell Tumor; Primary Meningeal Neoplasm; Primary Meningeal Tumor; Tumor of Meningothelial Cells

Definition

A neoplasm that arises from meningothelial cells. This category refers to meningiomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMeningothelial Cell Neoplasm

Professional guidelines

PubMed

Optic nerve sheath meningiomas: clinical features, functional prognosis and controversial treatment.
Castel A, Boschi A, Renard L, De Potter P
Bull Soc Belge Ophtalmol 2000;275:73-8. PMID: 10853310
Rudimentary meningocele of the skin. Clinicopathologic features and differential diagnosis.
Marrogi AJ, Swanson PE, Kyriakos M, Wick MR
J Cutan Pathol 1991 Jun;18(3):178-88. doi: 10.1111/j.1600-0560.1991.tb00150.x. PMID: 1918505

Recent clinical studies

Etiology

Stereotactic Radiosurgery for Intracranial Meningiomas.
Pikis S, Mantziaris G, Dumot C, Xu Z, Sheehan J
Neurosurg Clin N Am 2023 Jul;34(3):455-462. Epub 2023 Apr 7 doi: 10.1016/j.nec.2023.02.010. PMID: 37210134
Surgical management of de novo metastatic meningioma of the spine: An underestimated issue for WHO grade II/III meningiomas.
Jia Q, Wu Z, Chu R, Zhao C, Wang T, Zhou Z, Cai X, Yang X, Xiao J
Clin Neurol Neurosurg 2021 Nov;210:106995. Epub 2021 Oct 22 doi: 10.1016/j.clineuro.2021.106995. PMID: 34715555
THE "-OMAS" and "-OPIAS":  Targeted and Philosophical Considerations Regarding Hamartomas, Choristomas, Teratomas, Ectopias, and Heterotopias in Pediatric Otorhinolaryngologic Pathology.
Ozolek JA, Tekkesin MS
Head Neck Pathol 2021 Mar;15(1):25-40. Epub 2021 Mar 15 doi: 10.1007/s12105-020-01251-y. PMID: 33723758Free PMC Article
Pathology of meningiomas.
Solomon DA, Pekmezci M
Handb Clin Neurol 2020;169:87-99. doi: 10.1016/B978-0-12-804280-9.00005-6. PMID: 32553300
Molecular alterations in meningiomas: Literature review.
Pereira BJA, Oba-Shinjo SM, de Almeida AN, Marie SKN
Clin Neurol Neurosurg 2019 Jan;176:89-96. Epub 2018 Dec 7 doi: 10.1016/j.clineuro.2018.12.004. PMID: 30553171

Diagnosis

Humps and bumps of head: review of meningiomas of the scalp.
Porumb-Andrese E, Costea CF, Macovei G, Dumitrescu GF, Blaj LA, Prutianu I, Cucu AI
Rom J Morphol Embryol 2023 Oct-Dec;64(4):467-473. doi: 10.47162/RJME.64.4.02. PMID: 38184826Free PMC Article
Meningioma and Other Meningeal Tumors.
Bailo M, Gagliardi F, Boari N, Spina A, Piloni M, Castellano A, Mortini P
Adv Exp Med Biol 2023;1405:73-97. doi: 10.1007/978-3-031-23705-8_3. PMID: 37452935
Histopathology of Meningiomas.
Raghunathan A, Giannini C
Adv Exp Med Biol 2023;1416:35-45. doi: 10.1007/978-3-031-29750-2_4. PMID: 37432618
Embryonal and non-meningothelial mesenchymal tumors of the central nervous system - Advances in diagnosis and prognostication.
Meredith DM, Alexandrescu S
Brain Pathol 2022 Jul;32(4):e13059. Epub 2022 Mar 9 doi: 10.1111/bpa.13059. PMID: 35266242Free PMC Article
Dedifferentiated Liposarcoma With Meningothelial-Like Whorls: Five Additional Cases and Review of the Literature.
Usman Tariq M, Kayani N, Moatter T, Din NU
Int J Surg Pathol 2020 Oct;28(7):749-758. Epub 2020 May 17 doi: 10.1177/1066896920921950. PMID: 32419561

Therapy

Stereotactic Radiosurgery for Intracranial Meningiomas.
Pikis S, Mantziaris G, Dumot C, Xu Z, Sheehan J
Neurosurg Clin N Am 2023 Jul;34(3):455-462. Epub 2023 Apr 7 doi: 10.1016/j.nec.2023.02.010. PMID: 37210134
Altered expression of E-Cadherin-related transcription factors indicates partial epithelial-mesenchymal transition in aggressive meningiomas.
Wallesch M, Pachow D, Blücher C, Firsching R, Warnke JP, Braunsdorf WEK, Kirches E, Mawrin C
J Neurol Sci 2017 Sep 15;380:112-121. Epub 2017 Jul 8 doi: 10.1016/j.jns.2017.07.009. PMID: 28870549
Pachymeningeal involvement in POEMS syndrome: dramatic cerebral MRI improvement after lenalidomide therapy.
Briani C, Manara R, Lessi F, Citton V, Zambello R, Adami F
Am J Hematol 2012 May;87(5):539-41. Epub 2012 Mar 3 doi: 10.1002/ajh.23148. PMID: 22389216
Radiation-associated xanthomatous meningioma in a child.
Ijiri R, Tanaka Y, Hara M, Sekido K
Childs Nerv Syst 2000 May;16(5):304-8. doi: 10.1007/s003810050519. PMID: 10883374
High-dose radiation-induced meningiomas following acute lymphoblastic leukemia in children.
Salvati M, Cervoni L, Artico M
Childs Nerv Syst 1996 May;12(5):266-9. doi: 10.1007/BF00261808. PMID: 8737803

Prognosis

Meningioma and Other Meningeal Tumors.
Bailo M, Gagliardi F, Boari N, Spina A, Piloni M, Castellano A, Mortini P
Adv Exp Med Biol 2023;1405:73-97. doi: 10.1007/978-3-031-23705-8_3. PMID: 37452935
Stereotactic Radiosurgery for Intracranial Meningiomas.
Pikis S, Mantziaris G, Dumot C, Xu Z, Sheehan J
Neurosurg Clin N Am 2023 Jul;34(3):455-462. Epub 2023 Apr 7 doi: 10.1016/j.nec.2023.02.010. PMID: 37210134
Embryonal and non-meningothelial mesenchymal tumors of the central nervous system - Advances in diagnosis and prognostication.
Meredith DM, Alexandrescu S
Brain Pathol 2022 Jul;32(4):e13059. Epub 2022 Mar 9 doi: 10.1111/bpa.13059. PMID: 35266242Free PMC Article
SMARCE1 mutation screening in classification of clear cell meningiomas.
Smith MJ, Ahn S, Lee JI, Bulman M, Plessis DD, Suh YL
Histopathology 2017 Apr;70(5):814-820. Epub 2017 Feb 2 doi: 10.1111/his.13135. PMID: 27891692
Optic nerve sheath meningiomas.
Dutton JJ
Surv Ophthalmol 1992 Nov-Dec;37(3):167-83. doi: 10.1016/0039-6257(92)90135-g. PMID: 1475751

Clinical prediction guides

The spectrum of rare central nervous system (CNS) tumors with EWSR1-non-ETS fusions: experience from three pediatric institutions with review of the literature.
Lopez-Nunez O, Cafferata B, Santi M, Ranganathan S, Pearce TM, Kulich SM, Bailey KM, Broniscer A, Rossi S, Zin A, Nasrallah MP, Li MM, Zhong Y, Miele E, Alaggio R, Surrey LF
Brain Pathol 2021 Jan;31(1):70-83. Epub 2020 Nov 6 doi: 10.1111/bpa.12900. PMID: 32997853Free PMC Article
Dedifferentiated Liposarcoma With Meningothelial-Like Whorls: Five Additional Cases and Review of the Literature.
Usman Tariq M, Kayani N, Moatter T, Din NU
Int J Surg Pathol 2020 Oct;28(7):749-758. Epub 2020 May 17 doi: 10.1177/1066896920921950. PMID: 32419561
Clinicopathologic features of minute pulmonary meningothelial-like nodules.
Asakawa A, Horio H, Hishima T, Yamamichi T, Okui M, Harada M
Asian Cardiovasc Thorac Ann 2017 Sep-Oct;25(7-8):509-512. Epub 2017 Sep 5 doi: 10.1177/0218492317731390. PMID: 28871800
Genetic landscape of meningioma.
Yuzawa S, Nishihara H, Tanaka S
Brain Tumor Pathol 2016 Oct;33(4):237-247. Epub 2016 Sep 13 doi: 10.1007/s10014-016-0271-7. PMID: 27624470
Secretory meningiomas.
Colakoğlu N, Demirtaş E, Oktar N, Yüntem N, Islekel S, Ozdamar N
J Neurooncol 2003 May;62(3):233-41. doi: 10.1023/a:1023319407645. PMID: 12777074

Recent systematic reviews

Distant metastases in meningioma: an underestimated problem.
Surov A, Gottschling S, Bolz J, Kornhuber M, Alfieri A, Holzhausen HJ, Abbas J, Kösling S
J Neurooncol 2013 May;112(3):323-7. Epub 2013 Feb 13 doi: 10.1007/s11060-013-1074-x. PMID: 23404622

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