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Metastatic Benign Neoplasm

MedGen UID:
235321
•Concept ID:
C1334712
•
Neoplastic Process

Definition

A very rare benign neoplasm that metastasizes inexplicably. This category includes metastasizing pleomorphic adenoma of the salivary gland and uterine corpus metastasizing leiomyoma. [from NCI]

Professional guidelines

PubMed

Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
ESMO Clinical Practice Guideline for the diagnosis, staging and treatment of patients with metastatic breast cancer.
Gennari A, André F, Barrios CH, Cortés J, de Azambuja E, DeMichele A, Dent R, Fenlon D, Gligorov J, Hurvitz SA, Im SA, Krug D, Kunz WG, Loi S, Penault-Llorca F, Ricke J, Robson M, Rugo HS, Saura C, Schmid P, Singer CF, Spanic T, Tolaney SM, Turner NC, Curigliano G, Loibl S, Paluch-Shimon S, Harbeck N; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2021 Dec;32(12):1475-1495. Epub 2021 Oct 19 doi: 10.1016/j.annonc.2021.09.019. PMID: 34678411
Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline.
Lenders JW, Duh QY, Eisenhofer G, Gimenez-Roqueplo AP, Grebe SK, Murad MH, Naruse M, Pacak K, Young WF Jr; Endocrine Society
J Clin Endocrinol Metab 2014 Jun;99(6):1915-42. doi: 10.1210/jc.2014-1498. PMID: 24893135

Recent clinical studies

Etiology

Giant Cell Tumor of Soft Tissue: A Rare Entity.
Mavrogenis AF, Tsukamoto S, Antoniadou T, Righi A, Errani C
Orthopedics 2019 Jul 1;42(4):e364-e369. doi: 10.3928/01477447-20190624-04. PMID: 31323108
Nivolumab with or without ipilimumab treatment for metastatic sarcoma (Alliance A091401): two open-label, non-comparative, randomised, phase 2 trials.
D'Angelo SP, Mahoney MR, Van Tine BA, Atkins J, Milhem MM, Jahagirdar BN, Antonescu CR, Horvath E, Tap WD, Schwartz GK, Streicher H
Lancet Oncol 2018 Mar;19(3):416-426. Epub 2018 Jan 19 doi: 10.1016/S1470-2045(18)30006-8. PMID: 29370992Free PMC Article
Melanoma progression.
Elder DE
Pathology 2016 Feb;48(2):147-54. Epub 2016 Jan 16 doi: 10.1016/j.pathol.2015.12.002. PMID: 27020387
Pathological grading for predicting metastasis in phaeochromocytoma and paraganglioma.
Kimura N, Takayanagi R, Takizawa N, Itagaki E, Katabami T, Kakoi N, Rakugi H, Ikeda Y, Tanabe A, Nigawara T, Ito S, Kimura I, Naruse M; Phaeochromocytoma Study Group in Japan
Endocr Relat Cancer 2014 Jun;21(3):405-14. Epub 2014 May 6 doi: 10.1530/ERC-13-0494. PMID: 24521857
Pediatric germ cell tumors.
Rescorla FJ
Semin Pediatr Surg 2012 Feb;21(1):51-60. doi: 10.1053/j.sempedsurg.2011.10.005. PMID: 22248970

Diagnosis

PRAME Expression in Melanocytic Tumors.
Lezcano C, Jungbluth AA, Nehal KS, Hollmann TJ, Busam KJ
Am J Surg Pathol 2018 Nov;42(11):1456-1465. doi: 10.1097/PAS.0000000000001134. PMID: 30045064Free PMC Article
Recurrent and metastatic congenital mesoblastic nephroma: where does the evidence stand?
Jehangir S, Kurian JJ, Selvarajah D, Thomas RJ, Holland AJA
Pediatr Surg Int 2017 Nov;33(11):1183-1188. Epub 2017 Aug 30 doi: 10.1007/s00383-017-4149-5. PMID: 28856451
Melanoma progression.
Elder DE
Pathology 2016 Feb;48(2):147-54. Epub 2016 Jan 16 doi: 10.1016/j.pathol.2015.12.002. PMID: 27020387
Ameloblastic Carcinoma.
Gunaratne DA, Coleman HG, Lim L, Morgan GJ
Am J Case Rep 2015 Jul 1;16:415-9. doi: 10.12659/AJCR.893918. PMID: 26126621Free PMC Article
Pathology of the pleura: what the pulmonologists need to know.
Cagle PT, Allen TC
Respirology 2011 Apr;16(3):430-8. doi: 10.1111/j.1440-1843.2011.01957.x. PMID: 21362105

Therapy

Metastatic uveal melanoma: The final frontier.
Rantala ES, Hernberg MM, Piperno-Neumann S, Grossniklaus HE, Kivelä TT
Prog Retin Eye Res 2022 Sep;90:101041. Epub 2022 Jan 6 doi: 10.1016/j.preteyeres.2022.101041. PMID: 34999237
Treatment Strategies for Oligometastatic Breast Cancer.
Nesbit EG, Donnelly ED, Strauss JB
Curr Treat Options Oncol 2021 Aug 23;22(10):94. doi: 10.1007/s11864-021-00889-2. PMID: 34426881
Checkpoint inhibitor therapy for metastatic triple-negative breast cancer.
Heeke AL, Tan AR
Cancer Metastasis Rev 2021 Jun;40(2):537-547. Epub 2021 Jun 8 doi: 10.1007/s10555-021-09972-4. PMID: 34101053Free PMC Article
Recent advances in medical therapy for metastatic urothelial cancer.
Yuasa T, Urakami S, Yonese J
Int J Clin Oncol 2018 Aug;23(4):599-607. Epub 2018 Mar 20 doi: 10.1007/s10147-018-1260-0. PMID: 29556919Free PMC Article
Rechallenge therapy and treatment holiday: different strategies in management of metastatic colorectal cancer.
Tonini G, Imperatori M, Vincenzi B, Frezza AM, Santini D
J Exp Clin Cancer Res 2013 Nov 18;32(1):92. doi: 10.1186/1756-9966-32-92. PMID: 24245912Free PMC Article

Prognosis

Association of Obesity With Survival Outcomes in Patients With Cancer: A Systematic Review and Meta-analysis.
Petrelli F, Cortellini A, Indini A, Tomasello G, Ghidini M, Nigro O, Salati M, Dottorini L, Iaculli A, Varricchio A, Rampulla V, Barni S, Cabiddu M, Bossi A, Ghidini A, Zaniboni A
JAMA Netw Open 2021 Mar 1;4(3):e213520. doi: 10.1001/jamanetworkopen.2021.3520. PMID: 33779745Free PMC Article
Recurrent and metastatic congenital mesoblastic nephroma: where does the evidence stand?
Jehangir S, Kurian JJ, Selvarajah D, Thomas RJ, Holland AJA
Pediatr Surg Int 2017 Nov;33(11):1183-1188. Epub 2017 Aug 30 doi: 10.1007/s00383-017-4149-5. PMID: 28856451
Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: a population-based study.
Cagney DN, Martin AM, Catalano PJ, Redig AJ, Lin NU, Lee EQ, Wen PY, Dunn IF, Bi WL, Weiss SE, Haas-Kogan DA, Alexander BM, Aizer AA
Neuro Oncol 2017 Oct 19;19(11):1511-1521. doi: 10.1093/neuonc/nox077. PMID: 28444227Free PMC Article
Pathological grading for predicting metastasis in phaeochromocytoma and paraganglioma.
Kimura N, Takayanagi R, Takizawa N, Itagaki E, Katabami T, Kakoi N, Rakugi H, Ikeda Y, Tanabe A, Nigawara T, Ito S, Kimura I, Naruse M; Phaeochromocytoma Study Group in Japan
Endocr Relat Cancer 2014 Jun;21(3):405-14. Epub 2014 May 6 doi: 10.1530/ERC-13-0494. PMID: 24521857
Lymphadenectomy in metastasectomy.
Dominguez-Ventura A, Nichols FC 3rd
Thorac Surg Clin 2006 May;16(2):139-43. doi: 10.1016/j.thorsurg.2005.12.001. PMID: 16805203

Clinical prediction guides

Ovarian tumors: a survey of selected advances of note during the life of this journal.
Young RH
Hum Pathol 2020 Jan;95:169-206. Epub 2019 Oct 22 doi: 10.1016/j.humpath.2019.09.002. PMID: 31654691
Do not break a sweat: avoiding pitfalls in the diagnosis of sweat gland tumors.
Brenn T
Mod Pathol 2020 Jan;33(Suppl 1):25-41. Epub 2019 Sep 26 doi: 10.1038/s41379-019-0377-7. PMID: 31558783
Prognostic and predictive markers in liver limited stage IV colorectal cancer.
Rehman AH, Jones RP, Poston G
Eur J Surg Oncol 2019 Dec;45(12):2251-2256. Epub 2019 Jun 27 doi: 10.1016/j.ejso.2019.06.038. PMID: 31279594
Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases.
Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH
Ann Surg 1999 Sep;230(3):309-18; discussion 318-21. doi: 10.1097/00000658-199909000-00004. PMID: 10493478Free PMC Article
PET in lung cancer.
Coleman RE
J Nucl Med 1999 May;40(5):814-20. PMID: 10319756

Recent systematic reviews

Stereotactic radiosurgery versus whole brain radiotherapy in patients with intracranial metastatic disease and small-cell lung cancer: a systematic review and meta-analysis.
Gaebe K, Li AY, Park A, Parmar A, Lok BH, Sahgal A, Chan KKW, Erickson AW, Das S
Lancet Oncol 2022 Jul;23(7):931-939. Epub 2022 May 26 doi: 10.1016/S1470-2045(22)00271-6. PMID: 35644163
Evidence-Based Clinical Practice Guidelines for Extramammary Paget Disease.
Kibbi N, Owen JL, Worley B, Wang JX, Harikumar V, Downing MB, Aasi SZ, Aung PP, Barker CA, Bolotin D, Bordeaux JS, Cartee TV, Chandra S, Cho NL, Choi JN, Chung KY, Cliby WA, Dorigo O, Eisen DB, Fujisawa Y, Golda N, Halfdanarson TR, Iavazzo C, Jiang SIB, Kanitakis J, Khan A, Kim JYS, Kuzel TM, Lawrence N, Leitao MM Jr, MacLean AB, Maher IA, Mittal BB, Nehal KS, Ozog DM, Pettaway CA, Ross JS, Rossi AM, Servaes S, Solomon MJ, Thomas VD, Tolia M, Voelzke BB, Waldman A, Wong MK, Zhou Y, Arai N, Brackett A, Ibrahim SA, Kang BY, Poon E, Alam M
JAMA Oncol 2022 Apr 1;8(4):618-628. doi: 10.1001/jamaoncol.2021.7148. PMID: 35050310
Indirect Comparisons of Efficacy between Combination Approaches in Metastatic Hormone-sensitive Prostate Cancer: A Systematic Review and Network Meta-analysis.
Sathianathen NJ, Koschel S, Thangasamy IA, Teh J, Alghazo O, Butcher G, Howard H, Kapoor J, Lawrentschuk N, Siva S, Azad A, Tran B, Bolton D, Murphy DG
Eur Urol 2020 Mar;77(3):365-372. Epub 2019 Nov 1 doi: 10.1016/j.eururo.2019.09.004. PMID: 31679970
Prostate Radiotherapy for Metastatic Hormone-sensitive Prostate Cancer: A STOPCAP Systematic Review and Meta-analysis.
Burdett S, Boevé LM, Ingleby FC, Fisher DJ, Rydzewska LH, Vale CL, van Andel G, Clarke NW, Hulshof MC, James ND, Parker CC, Parmar MK, Sweeney CJ, Sydes MR, Tombal B, Verhagen PC, Tierney JF; STOPCAP M1 Radiotherapy Collaborators
Eur Urol 2019 Jul;76(1):115-124. Epub 2019 Feb 28 doi: 10.1016/j.eururo.2019.02.003. PMID: 30826218Free PMC Article
Breast surgery for metastatic breast cancer.
Tosello G, Torloni MR, Mota BS, Neeman T, Riera R
Cochrane Database Syst Rev 2018 Mar 15;3(3):CD011276. doi: 10.1002/14651858.CD011276.pub2. PMID: 29542106Free PMC Article

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    Practice guidelines

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