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Minor Salivary Gland Carcinoma ex Pleomorphic Adenoma

MedGen UID:
235329
Concept ID:
C1334772
Neoplastic Process
Synonyms: Carcinoma ex Pleomorphic Adenoma of Minor Salivary Gland; Carcinoma ex Pleomorphic Adenoma of the Minor Salivary Gland

Definition

A carcinoma that arises from a pleomorphic adenoma in the minor salivary glands. Patients usually present with a history of a long-standing tumor mass which grew rapidly in the past few months. Patients with non-invasive or minimally invasive carcinoma have an excellent prognosis. In cases where there is invasion of the surrounding tissues, the clinical course is aggressive. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMinor Salivary Gland Carcinoma ex Pleomorphic Adenoma

Professional guidelines

PubMed

Erovic BM, Schopper C, Pammer J, Vormittag L, Maleki A, Brunner M, Heiduschka G, Grasl MCh, Thurnher D
Head Neck 2010 Sep;32(9):1167-72. doi: 10.1002/hed.21312. PMID: 20191625

Recent clinical studies

Etiology

Key S, Chia C, Hasan Z, Sundaresan P, Dwivedi RC, Riffat F
Oral Oncol 2022 Oct;133:106052. Epub 2022 Jul 31 doi: 10.1016/j.oraloncology.2022.106052. PMID: 35921695
Seok J, Hyun SJ, Jeong WJ, Ahn SH, Kim H, Jung YH
Ear Nose Throat J 2019 Sep;98(8):504-509. Epub 2019 Jun 13 doi: 10.1177/0145561319855376. PMID: 31189352
Mok Y, Min En N, Chwee Ming L, Petersson F
Head Neck 2016 Sep;38(9):E2483-9. Epub 2016 Apr 15 doi: 10.1002/hed.24462. PMID: 27080524
Trenkić Božinović M, Krasić D, Katić V, Krstić M
Med Glas (Zenica) 2015 Feb;12(1):73-8. PMID: 25669341
Pallagatti S, Sheikh S, Gupta D, Das A, Singh R
N Y State Dent J 2013 Jun-Jul;79(4):52-4. PMID: 24027900

Diagnosis

Rammal R, Batson B, Spector ME, Chiosea SI, Seethala RR
Head Neck Pathol 2024 May 22;18(1):44. doi: 10.1007/s12105-024-01650-5. PMID: 38775845Free PMC Article
Key S, Chia C, Hasan Z, Sundaresan P, Dwivedi RC, Riffat F
Oral Oncol 2022 Oct;133:106052. Epub 2022 Jul 31 doi: 10.1016/j.oraloncology.2022.106052. PMID: 35921695
Khanna D, Chaubal T, Bapat R, Abdulla AM, Philip ST, Arora S
Afr Health Sci 2019 Dec;19(4):3253-3263. doi: 10.4314/ahs.v19i4.50. PMID: 32127904Free PMC Article
Ord RA, Ghazali N
Oral Maxillofac Surg Clin North Am 2017 Aug;29(3):315-324. Epub 2017 May 24 doi: 10.1016/j.coms.2017.03.008. PMID: 28551337
Pallagatti S, Sheikh S, Gupta D, Das A, Singh R
N Y State Dent J 2013 Jun-Jul;79(4):52-4. PMID: 24027900

Therapy

Mark J, Wedell B, Dahlenfors R, Stenman G
Cancer Genet Cytogenet 1991 Aug;55(1):19-29. doi: 10.1016/0165-4608(91)90230-r. PMID: 1913603

Prognosis

Key S, Chia C, Hasan Z, Sundaresan P, Dwivedi RC, Riffat F
Oral Oncol 2022 Oct;133:106052. Epub 2022 Jul 31 doi: 10.1016/j.oraloncology.2022.106052. PMID: 35921695
Ord RA, Ghazali N
Oral Maxillofac Surg Clin North Am 2017 Aug;29(3):315-324. Epub 2017 May 24 doi: 10.1016/j.coms.2017.03.008. PMID: 28551337
Valstar MH, de Ridder M, van den Broek EC, Stuiver MM, van Dijk BAC, van Velthuysen MLF, Balm AJM, Smeele LE
Oral Oncol 2017 Mar;66:93-99. Epub 2017 Jan 23 doi: 10.1016/j.oraloncology.2017.01.004. PMID: 28249655
Mok Y, Min En N, Chwee Ming L, Petersson F
Head Neck 2016 Sep;38(9):E2483-9. Epub 2016 Apr 15 doi: 10.1002/hed.24462. PMID: 27080524
Pallagatti S, Sheikh S, Gupta D, Das A, Singh R
N Y State Dent J 2013 Jun-Jul;79(4):52-4. PMID: 24027900

Clinical prediction guides

Shiraishi T, Chikui T, Yoshida S, Okamura K, Hashimoto K, Fukui T, Kagawa T
Oral Radiol 2024 Apr;40(2):314-318. Epub 2023 Nov 30 doi: 10.1007/s11282-023-00724-4. PMID: 38032399
Seok J, Hyun SJ, Jeong WJ, Ahn SH, Kim H, Jung YH
Ear Nose Throat J 2019 Sep;98(8):504-509. Epub 2019 Jun 13 doi: 10.1177/0145561319855376. PMID: 31189352
Silva LP, da Silva LAB, Sedassari BT, de Sousa SCOM, Dos Santos Pereira J, de Souza LB, da Costa Miguel MC
Eur Arch Otorhinolaryngol 2018 Jun;275(6):1595-1600. Epub 2018 Mar 29 doi: 10.1007/s00405-018-4960-1. PMID: 29594385
Silva LP, Santana T, Sedassari BT, de Sousa SM, Sobral APV, Freitas RA, Barboza CAG, de Souza LB
Eur Arch Otorhinolaryngol 2017 Aug;274(8):3203-3209. Epub 2017 May 18 doi: 10.1007/s00405-017-4605-9. PMID: 28523411
Valstar MH, de Ridder M, van den Broek EC, Stuiver MM, van Dijk BAC, van Velthuysen MLF, Balm AJM, Smeele LE
Oral Oncol 2017 Mar;66:93-99. Epub 2017 Jan 23 doi: 10.1016/j.oraloncology.2017.01.004. PMID: 28249655

Recent systematic reviews

Key S, Chia C, Hasan Z, Sundaresan P, Dwivedi RC, Riffat F
Oral Oncol 2022 Oct;133:106052. Epub 2022 Jul 31 doi: 10.1016/j.oraloncology.2022.106052. PMID: 35921695

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