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Central nervous system anaplastic large cell lymphoma

MedGen UID:
235493
•Concept ID:
C1335476
•
Neoplastic Process
Synonyms: Anaplastic Central Nervous System Large Cell Lymphoma; anaplastic central nervous system large cell lymphoma; Anaplastic CNS Large Cell Lymphoma; anaplastic CNS large cell lymphoma; Anaplastic Large Cell Lymphoma of Central Nervous System; anaplastic large cell lymphoma of central nervous system; Anaplastic Large Cell Lymphoma of CNS; anaplastic large cell lymphoma of CNS; Anaplastic Large Cell Lymphoma of the Central Nervous System; anaplastic large cell lymphoma of the central nervous system; Anaplastic Large Cell Lymphoma of the CNS; anaplastic large cell lymphoma of the CNS; Central Nervous System Anaplastic Large Cell Lymphoma; central nervous system anaplastic large cell lymphoma; Primary Central Nervous System Anaplastic Large Cell Lymphoma; primary central nervous system anaplastic large cell lymphoma; Primary CNS Anaplastic Large Cell Lymphoma; primary CNS anaplastic large cell lymphoma
 
Monarch Initiative: MONDO:0006128

Definition

An anaplastic large cell lymphoma that affects the brain, meninges, or spinal cord. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral nervous system anaplastic large cell lymphoma

Professional guidelines

PubMed

Diagnosis and management of rare paediatric Non-Hodgkin lymphoma.
Xavier AC, Suzuki R, Attarbaschi A
Best Pract Res Clin Haematol 2023 Mar;36(1):101440. Epub 2023 Jan 15 doi: 10.1016/j.beha.2023.101440. PMID: 36907633
Diagnosis and Management of Cutaneous Lymphomas Including Cutaneous T-cell Lymphoma.
Zic JA
Med Clin North Am 2021 Jul;105(4):737-755. doi: 10.1016/j.mcna.2021.04.010. PMID: 34059248
Management of Non-Hodgkin Lymphoma: ICMR Consensus Document.
Thacker N, Bakhshi S, Chinnaswamy G, Vora T, Prasad M, Bansal D, Agarwala S, Kapoor G, Radhakrishnan V, Laskar S, Kaur T, Rath GK, Dhaliwal RS, Arora B
Indian J Pediatr 2017 May;84(5):382-392. Epub 2017 Apr 5 doi: 10.1007/s12098-017-2318-0. PMID: 28378140

Recent clinical studies

Etiology

Primary Central Nervous System Anaplastic Large Cell Lymphoma, ALK Positive.
Ahrendsen JT, Ta R, Li J, Weinberg OK, Ferry JA, Hasserjian RP, Meredith DM, Varma H, Sadigh S, Michaels PD
Am J Clin Pathol 2022 Aug 4;158(2):300-310. doi: 10.1093/ajcp/aqac046. PMID: 35460414
Targeted therapy for advanced anaplastic lymphoma kinase (<I>ALK</I>)-rearranged non-small cell lung cancer.
Cameron LB, Hitchen N, Chandran E, Morris T, Manser R, Solomon BJ, Jordan V
Cochrane Database Syst Rev 2022 Jan 7;1(1):CD013453. doi: 10.1002/14651858.CD013453.pub2. PMID: 34994987Free PMC Article
Primary central nervous system ALK-negative anaplastic large cell lymphoma: a case report and literature review.
Yuan C, Duan H, Wang Y, Zhang J, Ou J, Wang W, Zhang M
Ann Palliat Med 2022 Apr;11(4):1554-1560. Epub 2021 Jul 1 doi: 10.21037/apm-21-557. PMID: 34263607
Update on Pediatric and Young Adult Mature Lymphomas.
Mason EF, Kovach AE
Clin Lab Med 2021 Sep;41(3):359-387. Epub 2021 Jul 1 doi: 10.1016/j.cll.2021.03.018. PMID: 34304770
Primary breast lymphoma.
Cheah CY, Campbell BA, Seymour JF
Cancer Treat Rev 2014 Sep;40(8):900-8. Epub 2014 Jun 6 doi: 10.1016/j.ctrv.2014.05.010. PMID: 24953564

Diagnosis

Primary Central Nervous System Anaplastic Large Cell Lymphoma, ALK Positive.
Ahrendsen JT, Ta R, Li J, Weinberg OK, Ferry JA, Hasserjian RP, Meredith DM, Varma H, Sadigh S, Michaels PD
Am J Clin Pathol 2022 Aug 4;158(2):300-310. doi: 10.1093/ajcp/aqac046. PMID: 35460414
Primary central nervous system ALK-negative anaplastic large cell lymphoma: a case report and literature review.
Yuan C, Duan H, Wang Y, Zhang J, Ou J, Wang W, Zhang M
Ann Palliat Med 2022 Apr;11(4):1554-1560. Epub 2021 Jul 1 doi: 10.21037/apm-21-557. PMID: 34263607
Update on Pediatric and Young Adult Mature Lymphomas.
Mason EF, Kovach AE
Clin Lab Med 2021 Sep;41(3):359-387. Epub 2021 Jul 1 doi: 10.1016/j.cll.2021.03.018. PMID: 34304770
Diagnosis and Management of Cutaneous Lymphomas Including Cutaneous T-cell Lymphoma.
Zic JA
Med Clin North Am 2021 Jul;105(4):737-755. doi: 10.1016/j.mcna.2021.04.010. PMID: 34059248
Primary breast lymphoma.
Cheah CY, Campbell BA, Seymour JF
Cancer Treat Rev 2014 Sep;40(8):900-8. Epub 2014 Jun 6 doi: 10.1016/j.ctrv.2014.05.010. PMID: 24953564

Therapy

Targeted therapy for advanced anaplastic lymphoma kinase (<I>ALK</I>)-rearranged non-small cell lung cancer.
Cameron LB, Hitchen N, Chandran E, Morris T, Manser R, Solomon BJ, Jordan V
Cochrane Database Syst Rev 2022 Jan 7;1(1):CD013453. doi: 10.1002/14651858.CD013453.pub2. PMID: 34994987Free PMC Article
Primary central nervous system ALK-negative anaplastic large cell lymphoma: a case report and literature review.
Yuan C, Duan H, Wang Y, Zhang J, Ou J, Wang W, Zhang M
Ann Palliat Med 2022 Apr;11(4):1554-1560. Epub 2021 Jul 1 doi: 10.21037/apm-21-557. PMID: 34263607
Systemic Therapy for Lung Cancer Brain Metastases.
Pellerino A, Bruno F, Rudà R, Soffietti R
Curr Treat Options Oncol 2021 Oct 25;22(12):110. doi: 10.1007/s11864-021-00911-7. PMID: 34693454
Diagnosis and Management of Cutaneous Lymphomas Including Cutaneous T-cell Lymphoma.
Zic JA
Med Clin North Am 2021 Jul;105(4):737-755. doi: 10.1016/j.mcna.2021.04.010. PMID: 34059248
Receptor Tyrosine Kinases as Therapeutic Targets for Alcohol Use Disorder.
Hamada K, Lasek AW
Neurotherapeutics 2020 Jan;17(1):4-16. doi: 10.1007/s13311-019-00795-4. PMID: 31617071Free PMC Article

Prognosis

Primary Central Nervous System Anaplastic Large Cell Lymphoma, ALK Positive.
Ahrendsen JT, Ta R, Li J, Weinberg OK, Ferry JA, Hasserjian RP, Meredith DM, Varma H, Sadigh S, Michaels PD
Am J Clin Pathol 2022 Aug 4;158(2):300-310. doi: 10.1093/ajcp/aqac046. PMID: 35460414
Diagnosis and Management of Cutaneous Lymphomas Including Cutaneous T-cell Lymphoma.
Zic JA
Med Clin North Am 2021 Jul;105(4):737-755. doi: 10.1016/j.mcna.2021.04.010. PMID: 34059248
Primary and secondary central nervous system mature T- and NK-cell lymphomas.
Pang Y, Chihara D
Semin Hematol 2021 Apr;58(2):123-129. Epub 2021 Mar 3 doi: 10.1053/j.seminhematol.2021.02.003. PMID: 33906722
Prognostic factors in paediatric anaplastic large cell lymphoma: role of ALK.
Damm-Welk C, Pillon M, Woessmann W, Mussolin L
Front Biosci (Schol Ed) 2015 Jun 1;7(2):205-16. doi: 10.2741/S434. PMID: 25961696
Primary central nervous system lymphoma.
Bhagavathi S, Wilson JD
Arch Pathol Lab Med 2008 Nov;132(11):1830-4. doi: 10.5858/132.11.1830. PMID: 18976024

Clinical prediction guides

Primary Central Nervous System Anaplastic Large Cell Lymphoma, ALK Positive.
Ahrendsen JT, Ta R, Li J, Weinberg OK, Ferry JA, Hasserjian RP, Meredith DM, Varma H, Sadigh S, Michaels PD
Am J Clin Pathol 2022 Aug 4;158(2):300-310. doi: 10.1093/ajcp/aqac046. PMID: 35460414
Comparative outcomes for mature T-cell and NK/T-cell lymphomas in people with and without HIV and to AIDS-defining lymphomas.
Koh MJ, Merrill MH, Koh MJ, Stuver R, Alonso CD, Foss FM, Mayor AM, Gill J, Epeldegui M, Cachay E, Thorne JE, Silverberg MJ, Horberg MA, Althoff KN, Nijhawan AE, McGinnis KA, Lee JS, Rabkin CS, Napravnik S, Li J, Castilho JL, Shen C, Jain S
Blood Adv 2022 Mar 8;6(5):1420-1431. doi: 10.1182/bloodadvances.2021006208. PMID: 35026839Free PMC Article
Clinicopathologic and Genetic Features of Primary T-cell Lymphomas of the Central Nervous System: An Analysis of 11 Cases Using Targeted Gene Sequencing.
Yim J, Koh J, Kim S, Song SG, Bae JM, Yun H, Sung JY, Kim TM, Park SH, Jeon YK
Am J Surg Pathol 2022 Apr 1;46(4):486-497. doi: 10.1097/PAS.0000000000001859. PMID: 34980830Free PMC Article
Systemic Therapy for Lung Cancer Brain Metastases.
Pellerino A, Bruno F, Rudà R, Soffietti R
Curr Treat Options Oncol 2021 Oct 25;22(12):110. doi: 10.1007/s11864-021-00911-7. PMID: 34693454
Central nervous system involvement in T-cell lymphoma: A single center experience.
Gurion R, Mehta N, Migliacci JC, Zelenetz A, Moskowitz A, Lunning M, Moskowitz C, Hamlin P, Horwitz S
Acta Oncol 2016 May;55(5):561-6. Epub 2016 Apr 4 doi: 10.3109/0284186X.2015.1118656. PMID: 27046135Free PMC Article

Recent systematic reviews

Targeted therapy for advanced anaplastic lymphoma kinase (<I>ALK</I>)-rearranged non-small cell lung cancer.
Cameron LB, Hitchen N, Chandran E, Morris T, Manser R, Solomon BJ, Jordan V
Cochrane Database Syst Rev 2022 Jan 7;1(1):CD013453. doi: 10.1002/14651858.CD013453.pub2. PMID: 34994987Free PMC Article

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