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Kidney leiomyosarcoma

MedGen UID:
235545
•Concept ID:
C1335743
•
Neoplastic Process
Synonyms: Kidney Leiomyosarcoma; kidney leiomyosarcoma; Leiomyosarcoma of Kidney; leiomyosarcoma of kidney; Leiomyosarcoma of the Kidney; leiomyosarcoma of the kidney; Renal Leiomyosarcoma; renal leiomyosarcoma
 
Monarch Initiative: MONDO:0003373

Definition

An aggressive malignant smooth muscle neoplasm, arising from the kidney. It is characterized by a proliferation of neoplastic spindle cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVKidney leiomyosarcoma

Professional guidelines

PubMed

Practical Management of Adult Ultra-Rare Primary Retroperitoneal Soft Tissue Sarcoma: A Focus on Perivascular Epithelioid Tumours and Extraosseous Ewing Sarcoma.
Apte SS, Mor E, Mitchell C, Gyorki DE
Curr Oncol 2023 Jun 21;30(7):5953-5972. doi: 10.3390/curroncol30070445. PMID: 37504306Free PMC Article
Systematic review of ablation techniques for the treatment of malignant or aggressive benign lesions in children.
Gómez FM, Patel PA, Stuart S, Roebuck DJ
Pediatr Radiol 2014 Oct;44(10):1281-9. Epub 2014 May 13 doi: 10.1007/s00247-014-3001-5. PMID: 24821394
Diagnosis and treatment of primary adult renal sarcoma.
Huang ZM, Li HZ, Ji ZG, Shi BB
Chin Med Sci J 2011 Sep;26(3):172-4. doi: 10.1016/s1001-9294(11)60044-8. PMID: 22207927

Recent clinical studies

Diagnosis

Kidney Graft Leiomyosarcoma: A Case Report.
Laranjinha I, Matias P, Jorge C, Birne R, Weigert A, Adragão T, Bruges M, Cabrera RA, Cassis J, Ramos S, Nogueira A, Godinho J, Messias H, Machado D
Transplant Proc 2016 Sep;48(7):2379-2383. doi: 10.1016/j.transproceed.2016.06.005. PMID: 27742302
Primary leiomyosarcoma of a horseshoe kidney in a woman with Turner syndrome: a case report.
Tanaka T, Koie T, Iwabuchi I, Ogasawara M, Kawaguchi T, Ohyama C
BMC Res Notes 2014 Aug 4;7:491. doi: 10.1186/1756-0500-7-491. PMID: 25090932Free PMC Article
Development of leiomyosarcoma from primary leiomyoma?
Loertzer H, Krause U, Holzhausen HJ, Hamza A, Fornara P
Urol Int 2004;73(3):276-9. doi: 10.1159/000080842. PMID: 15539851

Therapy

Kidney Graft Leiomyosarcoma: A Case Report.
Laranjinha I, Matias P, Jorge C, Birne R, Weigert A, Adragão T, Bruges M, Cabrera RA, Cassis J, Ramos S, Nogueira A, Godinho J, Messias H, Machado D
Transplant Proc 2016 Sep;48(7):2379-2383. doi: 10.1016/j.transproceed.2016.06.005. PMID: 27742302

Prognosis

Kidney Graft Leiomyosarcoma: A Case Report.
Laranjinha I, Matias P, Jorge C, Birne R, Weigert A, Adragão T, Bruges M, Cabrera RA, Cassis J, Ramos S, Nogueira A, Godinho J, Messias H, Machado D
Transplant Proc 2016 Sep;48(7):2379-2383. doi: 10.1016/j.transproceed.2016.06.005. PMID: 27742302
Pleomorphic leiomyosarcoma with a dedifferentiation-like appearance in the kidney: case report and literature review.
Tajima S, Waki M, Fukuyama M
Med Mol Morphol 2016 Dec;49(4):238-242. Epub 2015 Apr 25 doi: 10.1007/s00795-015-0103-6. PMID: 25910609
Development of leiomyosarcoma from primary leiomyoma?
Loertzer H, Krause U, Holzhausen HJ, Hamza A, Fornara P
Urol Int 2004;73(3):276-9. doi: 10.1159/000080842. PMID: 15539851

Clinical prediction guides

Pleomorphic leiomyosarcoma with a dedifferentiation-like appearance in the kidney: case report and literature review.
Tajima S, Waki M, Fukuyama M
Med Mol Morphol 2016 Dec;49(4):238-242. Epub 2015 Apr 25 doi: 10.1007/s00795-015-0103-6. PMID: 25910609

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