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Stage IVB Pharyngeal Cancer

MedGen UID:
236929
Concept ID:
C1336390
Neoplastic Process
Synonyms: Pharyngeal Cancer Stage IVB; Stage IVB Carcinoma of Pharynx; Stage IVB Carcinoma of the Pharynx; Stage IVB Pharyngeal Carcinoma; Stage IVB Pharynx Carcinoma

Definition

Stage IVB carcinoma of the pharynx according to the American Joint Committee on Cancer, 6th, 7th, and 8th editions. [from NCI]

Professional guidelines

PubMed

Tsai YT, Chen WC, Chien CY, Hsu CM, Lee YC, Tsai MS, Lin MH, Lai CH, Chang KP
World J Surg Oncol 2020 May 1;18(1):82. doi: 10.1186/s12957-020-01866-z. PMID: 32357934Free PMC Article
Cui T, Ward MC, Joshi NP, Woody NM, Murray EJ, Potter J, Dorfmeyer AA, Greskovich JF Jr, Koyfman SA, Xia P
Head Neck 2019 Apr;41(4):1096-1103. Epub 2019 Jan 31 doi: 10.1002/hed.25594. PMID: 30702180
Taguchi T, Nishimura G, Takahashi M, Shiono O, Komatsu M, Sano D, Yabuki KI, Arai Y, Yamashita Y, Yamamoto K, Sakuma Y, Oridate N
Int J Clin Oncol 2016 Oct;21(5):869-874. Epub 2016 Feb 23 doi: 10.1007/s10147-016-0964-2. PMID: 26908193

Recent clinical studies

Etiology

Xiang L, Rong JF, Xin-Chen, Li XY, Zheng Y, Ren PR, Lin S, Wen QL, He LJ, Zhang JW, Shang CL, Yang HR, Fan J, Pang HW, Zhang J, Tan BX, Zhang L, Du XB, Wen SM, Jiang L, Qin G, Wu JB
Int J Radiat Oncol Biol Phys 2023 Nov 15;117(4):914-924. Epub 2023 Jun 24 doi: 10.1016/j.ijrobp.2023.06.001. PMID: 37356553
de Sousa LG, Lazar Neto F, Dal Lago EA, Sikora A, Hanna E, Moreno A, Phan J, Glisson BS, Bell D, Ferrarotto R
Oral Oncol 2023 Mar;138:106311. Epub 2023 Jan 24 doi: 10.1016/j.oraloncology.2023.106311. PMID: 36702015
Li WZ, Lv X, Hu D, Lv SH, Liu GY, Liang H, Ye YF, Yang W, Zhang HX, Yuan TZ, Wang DS, Lu N, Ke LR, Tang WB, Tong LH, Chen ZJ, Liu T, Cao KJ, Mo HY, Guo L, Zhao C, Chen MY, Chen QY, Huang PY, Sun R, Qiu F, Luo DH, Wang L, Hua YJ, Tang LQ, Qian CN, Mai HQ, Guo X, Xiang YQ, Xia WX
JAMA Oncol 2022 May 1;8(5):706-714. doi: 10.1001/jamaoncol.2022.0122. PMID: 35323856Free PMC Article
Luo X, Huang X, Liu S, Wang X, Luo J, Xiao J, Wang K, Qu Y, Chen X, Zhang Y, Wang J, Zhang J, Xu G, Gao L, Wu R, Yi J
JAMA Netw Open 2022 Feb 1;5(2):e220165. doi: 10.1001/jamanetworkopen.2022.0165. PMID: 35191967Free PMC Article
Sun Y, Li WF, Chen NY, Zhang N, Hu GQ, Xie FY, Sun Y, Chen XZ, Li JG, Zhu XD, Hu CS, Xu XY, Chen YY, Hu WH, Guo L, Mo HY, Chen L, Mao YP, Sun R, Ai P, Liang SB, Long GX, Zheng BM, Feng XL, Gong XC, Li L, Shen CY, Xu JY, Guo Y, Chen YM, Zhang F, Lin L, Tang LL, Liu MZ, Ma J
Lancet Oncol 2016 Nov;17(11):1509-1520. Epub 2016 Sep 27 doi: 10.1016/S1470-2045(16)30410-7. PMID: 27686945

Diagnosis

Yang SP, Lin XY, Hu M, Cai CF
JMIR Public Health Surveill 2022 Dec 16;8(12):e40185. doi: 10.2196/40185. PMID: 36525304Free PMC Article
Jiang C, Gong B, Gao H, Zhang T, Li Z, Wang J, Zhang L
Radiother Oncol 2021 Aug;161:23-28. Epub 2021 May 25 doi: 10.1016/j.radonc.2021.05.020. PMID: 34044063
Balica NC, Poenaru M, Doroş CI, Baderca F, Preda MA, Iovan VC, Stanca HT, Busuioc CJ, Oprişcan IC, Boruga O
Rom J Morphol Embryol 2018;59(1):113-119. PMID: 29940618
Katano A, Takahashi W, Yamashita H, Yamamoto K, Ando M, Yoshida M, Saito Y, Abe O, Nakagawa K
Medicine (Baltimore) 2018 May;97(18):e0502. doi: 10.1097/MD.0000000000010502. PMID: 29718841Free PMC Article
Yoshida EJ, Luu M, David JM, Kim S, Mita A, Scher K, Shiao SL, Tighiouart M, Lee NY, Ho AS, Zumsteg ZS
Int J Radiat Oncol Biol Phys 2018 Feb 1;100(2):408-417. Epub 2017 Sep 28 doi: 10.1016/j.ijrobp.2017.09.038. PMID: 29100787

Therapy

Xiang L, Rong JF, Xin-Chen, Li XY, Zheng Y, Ren PR, Lin S, Wen QL, He LJ, Zhang JW, Shang CL, Yang HR, Fan J, Pang HW, Zhang J, Tan BX, Zhang L, Du XB, Wen SM, Jiang L, Qin G, Wu JB
Int J Radiat Oncol Biol Phys 2023 Nov 15;117(4):914-924. Epub 2023 Jun 24 doi: 10.1016/j.ijrobp.2023.06.001. PMID: 37356553
Castelli J, Thariat J, Benezery K, Hasbini A, Gery B, Berger A, Liem X, Guihard S, Chapet S, Thureau S, Auberdiac P, Pommier P, Ruffier A, Perrier L, Devillers A, Campillo-Gimenez B, de Crevoisier R
JAMA Oncol 2023 Aug 1;9(8):1056-1064. doi: 10.1001/jamaoncol.2023.1352. PMID: 37261806Free PMC Article
Li WZ, Lv X, Hu D, Lv SH, Liu GY, Liang H, Ye YF, Yang W, Zhang HX, Yuan TZ, Wang DS, Lu N, Ke LR, Tang WB, Tong LH, Chen ZJ, Liu T, Cao KJ, Mo HY, Guo L, Zhao C, Chen MY, Chen QY, Huang PY, Sun R, Qiu F, Luo DH, Wang L, Hua YJ, Tang LQ, Qian CN, Mai HQ, Guo X, Xiang YQ, Xia WX
JAMA Oncol 2022 May 1;8(5):706-714. doi: 10.1001/jamaoncol.2022.0122. PMID: 35323856Free PMC Article
Cui T, Ward MC, Joshi NP, Woody NM, Murray EJ, Potter J, Dorfmeyer AA, Greskovich JF Jr, Koyfman SA, Xia P
Head Neck 2019 Apr;41(4):1096-1103. Epub 2019 Jan 31 doi: 10.1002/hed.25594. PMID: 30702180
Sun Y, Li WF, Chen NY, Zhang N, Hu GQ, Xie FY, Sun Y, Chen XZ, Li JG, Zhu XD, Hu CS, Xu XY, Chen YY, Hu WH, Guo L, Mo HY, Chen L, Mao YP, Sun R, Ai P, Liang SB, Long GX, Zheng BM, Feng XL, Gong XC, Li L, Shen CY, Xu JY, Guo Y, Chen YM, Zhang F, Lin L, Tang LL, Liu MZ, Ma J
Lancet Oncol 2016 Nov;17(11):1509-1520. Epub 2016 Sep 27 doi: 10.1016/S1470-2045(16)30410-7. PMID: 27686945

Prognosis

de Sousa LG, Lazar Neto F, Dal Lago EA, Sikora A, Hanna E, Moreno A, Phan J, Glisson BS, Bell D, Ferrarotto R
Oral Oncol 2023 Mar;138:106311. Epub 2023 Jan 24 doi: 10.1016/j.oraloncology.2023.106311. PMID: 36702015
Yang SP, Lin XY, Hu M, Cai CF
JMIR Public Health Surveill 2022 Dec 16;8(12):e40185. doi: 10.2196/40185. PMID: 36525304Free PMC Article
Hong RL, Hsiao CF, Ting LL, Ko JY, Wang CW, Chang JTC, Lou PJ, Wang HM, Tsai MH, Lai SC, Liu TW
Ann Oncol 2018 Sep 1;29(9):1972-1979. doi: 10.1093/annonc/mdy249. PMID: 30016391
Zhang L, Chen QY, Liu H, Tang LQ, Mai HQ
Drug Des Devel Ther 2013;7:37-52. Epub 2013 Feb 1 doi: 10.2147/DDDT.S30753. PMID: 23403548Free PMC Article
Bensouda Y, Kaikani W, Ahbeddou N, Rahhali R, Jabri M, Mrabti H, Boussen H, Errihani H
Eur Ann Otorhinolaryngol Head Neck Dis 2011 Apr;128(2):79-85. Epub 2010 Dec 21 doi: 10.1016/j.anorl.2010.10.003. PMID: 21177151

Clinical prediction guides

Liang YJ, Chen QY, Xu JX, Liu XF, Xia JC, Liu LT, Guo SS, Song B, Wang P, Li JB, Liu Q, Mo HY, Guo L, Sun R, Luo DH, He J, Liu YN, Nie CP, Tang LQ, Li J, Mai HQ
Eur J Cancer 2023 Sep;191:112965. Epub 2023 Jul 5 doi: 10.1016/j.ejca.2023.112965. PMID: 37540921
Yang SP, Lin XY, Hu M, Cai CF
JMIR Public Health Surveill 2022 Dec 16;8(12):e40185. doi: 10.2196/40185. PMID: 36525304Free PMC Article
Chan DCT, Lam WKJ, Hui EP, Ma BBY, Chan CML, Lee VCT, Cheng SH, Gai W, Jiang P, Wong KCW, Mo F, Zee B, King AD, Le QT, Chan ATC, Chan KCA, Lo YMD
Ann Oncol 2022 Aug;33(8):794-803. Epub 2022 Apr 29 doi: 10.1016/j.annonc.2022.04.068. PMID: 35491007
Vijayvargiya P, Trivedi S, Rupji M, Song H, Liu Y, Jiang R, Kaka AS, Chen GZ, Stokes W, Steuer C, Shin DM, Beitler JJ, Patel MR, Aiken A, Saba NF
Oncologist 2022 Feb 3;27(1):48-56. doi: 10.1093/oncolo/oyab001. PMID: 35305095Free PMC Article
Katano A, Takahashi W, Yamashita H, Yamamoto K, Ando M, Yoshida M, Saito Y, Abe O, Nakagawa K
Medicine (Baltimore) 2018 May;97(18):e0502. doi: 10.1097/MD.0000000000010502. PMID: 29718841Free PMC Article

Recent systematic reviews

Howard J, Dwivedi RC, Masterson L, Kothari P, Quon H, Holsinger FC
Cochrane Database Syst Rev 2018 Dec 14;12(12):CD012939. doi: 10.1002/14651858.CD012939.pub2. PMID: 30550641Free PMC Article

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