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Thyroid Gland Immunoblastic Lymphoma

MedGen UID:
237010
•Concept ID:
C1336752
•
Neoplastic Process
Synonyms: Immunoblastic Lymphoma of the Thyroid; Immunoblastic Lymphoma of the Thyroid Gland; Immunoblastic Lymphoma of Thyroid; Immunoblastic Lymphoma of Thyroid Gland; Primary Thyroid Gland Immunoblastic Lymphoma; Thyroid Immunoblastic Lymphoma

Definition

A diffuse large B-cell lymphoma variant, primarily involving the thyroid gland. It is composed predominantly of immunoblasts. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThyroid Gland Immunoblastic Lymphoma

Recent clinical studies

Etiology

Immunohistochemical analysis of small cell tumors of the thyroid gland: an Eastern Cooperative Oncology Group study.
Wolf BC, Sheahan K, DeCoste D, Variakojis D, Alpern HD, Haselow RE
Hum Pathol 1992 Nov;23(11):1252-61. doi: 10.1016/0046-8177(92)90293-c. PMID: 1330875
Malignant lymphomas of the thyroid gland. Analysis of 79 patients with emphasis on histologic prognostic factors.
Aozasa K, Inoue A, Tajima K, Miyauchi A, Matsuzuka F, Kuma K
Cancer 1986 Jul 1;58(1):100-4. doi: 10.1002/1097-0142(19860701)58:1<100::aid-cncr2820580118>3.0.co;2-1. PMID: 3708539

Diagnosis

Non-Hodgkin's lymphoma presenting as thyroid and adrenal gland involvement.
Erdoğan G, Güllü S, Colak T, Kamel AN, Başkal N, Ekinci C
Endocr J 1997 Feb;44(1):199-203. doi: 10.1507/endocrj.44.199. PMID: 9152635
Localized non-Hodgkin's lymphoma of the adrenal and thyroid glands.
Baskal N, Erdogan G, Kamel AN, Dagci SS, Akyar S, Ekinci C
Endocrinol Jpn 1992 Jun;39(3):269-76. doi: 10.1507/endocrj1954.39.269. PMID: 1385105
Immunohistochemical analysis of small cell tumors of the thyroid gland: an Eastern Cooperative Oncology Group study.
Wolf BC, Sheahan K, DeCoste D, Variakojis D, Alpern HD, Haselow RE
Hum Pathol 1992 Nov;23(11):1252-61. doi: 10.1016/0046-8177(92)90293-c. PMID: 1330875
Primary lymphoma of the thyroid: a clinical, histological and immunohistochemical study of 20 cases.
Mizukami Y, Michigishi T, Nonomura A, Nakamura S, Hashimoto T, Katsuda S, Otake S, Matsubara F
Histopathology 1990 Sep;17(3):201-9. doi: 10.1111/j.1365-2559.1990.tb00708.x. PMID: 2242848

Therapy

Non-Hodgkin's lymphoma presenting as thyroid and adrenal gland involvement.
Erdoğan G, Güllü S, Colak T, Kamel AN, Başkal N, Ekinci C
Endocr J 1997 Feb;44(1):199-203. doi: 10.1507/endocrj.44.199. PMID: 9152635
Localized non-Hodgkin's lymphoma of the adrenal and thyroid glands.
Baskal N, Erdogan G, Kamel AN, Dagci SS, Akyar S, Ekinci C
Endocrinol Jpn 1992 Jun;39(3):269-76. doi: 10.1507/endocrj1954.39.269. PMID: 1385105

Prognosis

Localized non-Hodgkin's lymphoma of the adrenal and thyroid glands.
Baskal N, Erdogan G, Kamel AN, Dagci SS, Akyar S, Ekinci C
Endocrinol Jpn 1992 Jun;39(3):269-76. doi: 10.1507/endocrj1954.39.269. PMID: 1385105
Malignant lymphomas of the thyroid gland. Analysis of 79 patients with emphasis on histologic prognostic factors.
Aozasa K, Inoue A, Tajima K, Miyauchi A, Matsuzuka F, Kuma K
Cancer 1986 Jul 1;58(1):100-4. doi: 10.1002/1097-0142(19860701)58:1<100::aid-cncr2820580118>3.0.co;2-1. PMID: 3708539

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