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Well Differentiated Malignant Neoplasm

MedGen UID:
237061
•Concept ID:
C1337019
•
Neoplastic Process

Definition

A neoplasm whose histologic characteristics are similar to the tissue from which it arose. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVWell Differentiated Malignant Neoplasm

Professional guidelines

PubMed

Myeloid Sarcoma: Presentation, Diagnosis, and Treatment.
Almond LM, Charalampakis M, Ford SJ, Gourevitch D, Desai A
Clin Lymphoma Myeloma Leuk 2017 May;17(5):263-267. Epub 2017 Mar 7 doi: 10.1016/j.clml.2017.02.027. PMID: 28342811
Unexplained Lymphadenopathy: Evaluation and Differential Diagnosis.
Gaddey HL, Riegel AM
Am Fam Physician 2016 Dec 1;94(11):896-903. PMID: 27929264
Mesenteric tumors: diagnosis and treatment.
Dufay C, Abdelli A, Le Pennec V, Chiche L
J Visc Surg 2012 Aug;149(4):e239-51. Epub 2012 Jul 15 doi: 10.1016/j.jviscsurg.2012.05.005. PMID: 22796300

Recent clinical studies

Etiology

Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET.
Zhang Q, Yao B, Long X, Chen Z, He M, Wu Y, Qiao N, Ma Z, Ye Z, Zhang Y, Yao S, Wang Y, Cheng H, Chen H, Ye H, Wang Y, Li Y, Chen J, Zhang Z, Guo F, Zhao Y
Cell Rep Med 2023 Feb 21;4(2):100934. Epub 2023 Feb 7 doi: 10.1016/j.xcrm.2023.100934. PMID: 36754052Free PMC Article
Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.
Cheng WY, Li JF, Zhu YM, Lin XJ, Wen LJ, Zhang F, Zhang YL, Zhao M, Fang H, Wang SY, Lin XJ, Qiao N, Yin W, Zhang JN, Dai YT, Jiang L, Sun XJ, Xu Y, Zhang TT, Chen SN, Zhu HH, Chen Z, Jin J, Wu DP, Shen Y, Chen SJ
Proc Natl Acad Sci U S A 2022 Dec 6;119(49):e2211429119. Epub 2022 Nov 28 doi: 10.1073/pnas.2211429119. PMID: 36442087Free PMC Article
Vitamin D and the risk for cancer: A molecular analysis.
Carlberg C, Velleuer E
Biochem Pharmacol 2022 Feb;196:114735. Epub 2021 Aug 16 doi: 10.1016/j.bcp.2021.114735. PMID: 34411566
Interpretation of T cell states from single-cell transcriptomics data using reference atlases.
Andreatta M, Corria-Osorio J, Müller S, Cubas R, Coukos G, Carmona SJ
Nat Commun 2021 May 20;12(1):2965. doi: 10.1038/s41467-021-23324-4. PMID: 34017005Free PMC Article
Current practice in patients with differentiated thyroid cancer.
Schlumberger M, Leboulleux S
Nat Rev Endocrinol 2021 Mar;17(3):176-188. Epub 2020 Dec 18 doi: 10.1038/s41574-020-00448-z. PMID: 33339988

Diagnosis

Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.
Cheng WY, Li JF, Zhu YM, Lin XJ, Wen LJ, Zhang F, Zhang YL, Zhao M, Fang H, Wang SY, Lin XJ, Qiao N, Yin W, Zhang JN, Dai YT, Jiang L, Sun XJ, Xu Y, Zhang TT, Chen SN, Zhu HH, Chen Z, Jin J, Wu DP, Shen Y, Chen SJ
Proc Natl Acad Sci U S A 2022 Dec 6;119(49):e2211429119. Epub 2022 Nov 28 doi: 10.1073/pnas.2211429119. PMID: 36442087Free PMC Article
Current practice in patients with differentiated thyroid cancer.
Schlumberger M, Leboulleux S
Nat Rev Endocrinol 2021 Mar;17(3):176-188. Epub 2020 Dec 18 doi: 10.1038/s41574-020-00448-z. PMID: 33339988
Clinical and Molecular Spectrum of Liposarcoma.
Lee ATJ, Thway K, Huang PH, Jones RL
J Clin Oncol 2018 Jan 10;36(2):151-159. Epub 2017 Dec 8 doi: 10.1200/JCO.2017.74.9598. PMID: 29220294Free PMC Article
Introduction to the diagnosis and classification of monocytic-lineage leukemias by flow cytometry.
Matarraz S, Almeida J, Flores-Montero J, Lécrevisse Q, Guerri V, López A, Bárrena S, Van Der Velden VHJ, Te Marvelde JG, Van Dongen JJM, Orfao A
Cytometry B Clin Cytom 2017 May;92(3):218-227. Epub 2015 Aug 18 doi: 10.1002/cyto.b.21219. PMID: 26282340
Pancreatic Neuroendocrine Tumors.
Salaria SN, Shi C
Surg Pathol Clin 2016 Dec;9(4):595-617. Epub 2016 Oct 12 doi: 10.1016/j.path.2016.05.006. PMID: 27926362

Therapy

Vitamin D and the risk for cancer: A molecular analysis.
Carlberg C, Velleuer E
Biochem Pharmacol 2022 Feb;196:114735. Epub 2021 Aug 16 doi: 10.1016/j.bcp.2021.114735. PMID: 34411566
Current practice in patients with differentiated thyroid cancer.
Schlumberger M, Leboulleux S
Nat Rev Endocrinol 2021 Mar;17(3):176-188. Epub 2020 Dec 18 doi: 10.1038/s41574-020-00448-z. PMID: 33339988
The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy.
Yuan J, Dong X, Yap J, Hu J
J Hematol Oncol 2020 Aug 17;13(1):113. doi: 10.1186/s13045-020-00949-4. PMID: 32807225Free PMC Article
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.
Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, Woo G, Fang L, Santisakultarm TP, Manor U, Xu R, Becerra CR, Borazanci E, Von Hoff DD, Grandgenett PM, Hollingsworth MA, Leblanc M, Umetsu SE, Collisson EA, Scadeng M, Lowy AM, Donahue TR, Reya T, Downes M, Evans RM, Wahl GM, Pawson T, Tian R, Hunter T
Nature 2019 May;569(7754):131-135. Epub 2019 Apr 17 doi: 10.1038/s41586-019-1130-6. PMID: 30996350Free PMC Article
The success and the challenge of all-trans retinoic acid in the treatment of cancer.
Ni X, Hu G, Cai X
Crit Rev Food Sci Nutr 2019;59(sup1):S71-S80. Epub 2018 Oct 2 doi: 10.1080/10408398.2018.1509201. PMID: 30277803

Prognosis

Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.
Cheng WY, Li JF, Zhu YM, Lin XJ, Wen LJ, Zhang F, Zhang YL, Zhao M, Fang H, Wang SY, Lin XJ, Qiao N, Yin W, Zhang JN, Dai YT, Jiang L, Sun XJ, Xu Y, Zhang TT, Chen SN, Zhu HH, Chen Z, Jin J, Wu DP, Shen Y, Chen SJ
Proc Natl Acad Sci U S A 2022 Dec 6;119(49):e2211429119. Epub 2022 Nov 28 doi: 10.1073/pnas.2211429119. PMID: 36442087Free PMC Article
Current practice in patients with differentiated thyroid cancer.
Schlumberger M, Leboulleux S
Nat Rev Endocrinol 2021 Mar;17(3):176-188. Epub 2020 Dec 18 doi: 10.1038/s41574-020-00448-z. PMID: 33339988
The success and the challenge of all-trans retinoic acid in the treatment of cancer.
Ni X, Hu G, Cai X
Crit Rev Food Sci Nutr 2019;59(sup1):S71-S80. Epub 2018 Oct 2 doi: 10.1080/10408398.2018.1509201. PMID: 30277803
Clinical and Molecular Spectrum of Liposarcoma.
Lee ATJ, Thway K, Huang PH, Jones RL
J Clin Oncol 2018 Jan 10;36(2):151-159. Epub 2017 Dec 8 doi: 10.1200/JCO.2017.74.9598. PMID: 29220294Free PMC Article
Pancreatic Neuroendocrine Tumors.
Salaria SN, Shi C
Surg Pathol Clin 2016 Dec;9(4):595-617. Epub 2016 Oct 12 doi: 10.1016/j.path.2016.05.006. PMID: 27926362

Clinical prediction guides

Application of single-cell sequencing to the research of tumor microenvironment.
Chen S, Zhou Z, Li Y, Du Y, Chen G
Front Immunol 2023;14:1285540. Epub 2023 Oct 27 doi: 10.3389/fimmu.2023.1285540. PMID: 37965341Free PMC Article
Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET.
Zhang Q, Yao B, Long X, Chen Z, He M, Wu Y, Qiao N, Ma Z, Ye Z, Zhang Y, Yao S, Wang Y, Cheng H, Chen H, Ye H, Wang Y, Li Y, Chen J, Zhang Z, Guo F, Zhao Y
Cell Rep Med 2023 Feb 21;4(2):100934. Epub 2023 Feb 7 doi: 10.1016/j.xcrm.2023.100934. PMID: 36754052Free PMC Article
Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.
Cheng WY, Li JF, Zhu YM, Lin XJ, Wen LJ, Zhang F, Zhang YL, Zhao M, Fang H, Wang SY, Lin XJ, Qiao N, Yin W, Zhang JN, Dai YT, Jiang L, Sun XJ, Xu Y, Zhang TT, Chen SN, Zhu HH, Chen Z, Jin J, Wu DP, Shen Y, Chen SJ
Proc Natl Acad Sci U S A 2022 Dec 6;119(49):e2211429119. Epub 2022 Nov 28 doi: 10.1073/pnas.2211429119. PMID: 36442087Free PMC Article
Pancreatic Neuroendocrine Tumors.
Salaria SN, Shi C
Surg Pathol Clin 2016 Dec;9(4):595-617. Epub 2016 Oct 12 doi: 10.1016/j.path.2016.05.006. PMID: 27926362
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, Pacini F, Randolph GW, Sawka AM, Schlumberger M, Schuff KG, Sherman SI, Sosa JA, Steward DL, Tuttle RM, Wartofsky L
Thyroid 2016 Jan;26(1):1-133. doi: 10.1089/thy.2015.0020. PMID: 26462967Free PMC Article

Recent systematic reviews

Microbiota and Thyroid Disease: An Updated Systematic Review.
Stramazzo I, Capriello S, Filardo S, Centanni M, Virili C
Adv Exp Med Biol 2023;1370:125-144. doi: 10.1007/5584_2023_770. PMID: 36971966
Androgen Receptor Signaling Inhibitors in Addition to Docetaxel with Androgen Deprivation Therapy for Metastatic Hormone-sensitive Prostate Cancer: A Systematic Review and Meta-analysis.
Yanagisawa T, Rajwa P, Thibault C, Gandaglia G, Mori K, Kawada T, Fukuokaya W, Shim SR, Mostafaei H, Motlagh RS, Quhal F, Laukhtina E, Pallauf M, Pradere B, Kimura T, Egawa S, Shariat SF
Eur Urol 2022 Dec;82(6):584-598. Epub 2022 Aug 19 doi: 10.1016/j.eururo.2022.08.002. PMID: 35995644
Radiomics can differentiate high-grade glioma from brain metastasis: a systematic review and meta-analysis.
Li Y, Liu Y, Liang Y, Wei R, Zhang W, Yao W, Luo S, Pang X, Wang Y, Jiang X, Lai S, Yang R
Eur Radiol 2022 Nov;32(11):8039-8051. Epub 2022 May 19 doi: 10.1007/s00330-022-08828-x. PMID: 35587827
Selenium for preventing cancer.
Vinceti M, Filippini T, Del Giovane C, Dennert G, Zwahlen M, Brinkman M, Zeegers MP, Horneber M, D'Amico R, Crespi CM
Cochrane Database Syst Rev 2018 Jan 29;1(1):CD005195. doi: 10.1002/14651858.CD005195.pub4. PMID: 29376219Free PMC Article
Extranasopharyngeal angiofibroma revisited.
Windfuhr JP, Vent J
Clin Otolaryngol 2018 Feb;43(1):199-222. Epub 2017 Aug 10 doi: 10.1111/coa.12939. PMID: 28714226

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