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Vascular purpura

MedGen UID:
237145
•Concept ID:
C1368065
•
Pathologic Function
Synonym: Vascular Purpura
SNOMED CT: Vascular purpura (21112004)

Definition

A raised vasculitic hemorrhage into the skin and/or mucous membranes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVascular purpura

Professional guidelines

PubMed

Schönlein-henoch purpura in children and adults: diagnosis, pathophysiology and management.
Rostoker G
BioDrugs 2001;15(2):99-138. doi: 10.2165/00063030-200115020-00004. PMID: 11437679
Deflazacort in the treatment of haematologic disorders.
Gobbi M, Scudeletti M
Eur J Clin Pharmacol 1993;45 Suppl 1:S25-8. doi: 10.1007/BF01844200. PMID: 8313930

Recent clinical studies

Etiology

Cutaneous Involvement in Catastrophic Antiphospholipid Syndrome in a Multicenter Cohort of 65 Patients.
Dupré A, Morel N, Yelnik C, Moguelet P, Le Guern V, Stammler R, Nguyen Y, Paule R, Dufrost V, Ackermann F, Benhamou Y, Godeau B, Lambert M, Duffau P, Mekinian A, Saadoun D, Mouthon L, Hachulla E, Maillard H, Levesque H, Morell-Dubois S, Leroux G, Piette JC, Chasset F, Costedoat-Chalumeau N
JAMA Dermatol 2023 Jan 1;159(1):62-67. doi: 10.1001/jamadermatol.2022.5221. PMID: 36477813Free PMC Article
Palpable purpura: is it associated with vasculitis or not? A single-center experience.
Kaynar Özçelik G, Içaçan OC, Yalçin Mutlu M, Yildirim F, Bes C
Clin Rheumatol 2022 May;41(5):1493-1498. Epub 2022 Jan 25 doi: 10.1007/s10067-022-06075-5. PMID: 35076788
Henoch-Schönlein Purpura with Posterior Reversible Encephalopathy Syndrome.
Stefek B, Beck M, Ioffreda M, Gardner L, Stefanski M
J Pediatr 2015 Nov;167(5):1152-4. Epub 2015 Aug 29 doi: 10.1016/j.jpeds.2015.07.066. PMID: 26323197
Musculoskeletal manifestations of scurvy.
Fain O
Joint Bone Spine 2005 Mar;72(2):124-8. doi: 10.1016/j.jbspin.2004.01.007. PMID: 15797491
Multicentric Castleman's disease, non-Hodgkin's lymphoma, and Kaposi's sarcoma: a rare simultaneous occurrence.
Sukpanichnant S, Sivayathorn A, Visudhiphan S, Ngowthammatas W
Asian Pac J Allergy Immunol 2002 Jun;20(2):127-33. PMID: 12403198

Diagnosis

Rare manifestations of cryoglobulinemic vasculitis: a case report.
Leleux C, Zerbib Y, Pommerolle P, Da Rocha A, Serpier M, Caillard P
Front Immunol 2023;14:1271584. Epub 2023 Oct 13 doi: 10.3389/fimmu.2023.1271584. PMID: 37901234Free PMC Article
Vasculitis-What Do We Have to Know? A Review of Literature.
Shavit E, Alavi A, Sibbald RG
Int J Low Extrem Wounds 2018 Dec;17(4):218-226. Epub 2018 Dec 3 doi: 10.1177/1534734618804982. PMID: 30501545
Vancomycin-associated Henoch-Schönlein purpura.
Min Z, Garcia RR, Murillo M, Uchin JM, Bhanot N
J Infect Chemother 2017 Mar;23(3):180-184. Epub 2016 Sep 25 doi: 10.1016/j.jiac.2016.08.012. PMID: 27681233
Musculoskeletal manifestations of scurvy.
Fain O
Joint Bone Spine 2005 Mar;72(2):124-8. doi: 10.1016/j.jbspin.2004.01.007. PMID: 15797491
Schönlein-henoch purpura in children and adults: diagnosis, pathophysiology and management.
Rostoker G
BioDrugs 2001;15(2):99-138. doi: 10.2165/00063030-200115020-00004. PMID: 11437679

Therapy

Steroid-resistant peripheral neuropathy in a child: a rare finding in immunoglobulin a vasculitis.
Aydın F, Kurt T, Ünlü E, Tekin ZE, Çelikel E, Acar BÇ
Turk J Pediatr 2022;64(3):576-579. doi: 10.24953/turkjped.2020.3094. PMID: 35899572
A Case of Leukocytoclastic Vasculitis Following SARS-COV-2 Vaccination.
Ball-Burack MR, Kosowsky JM
J Emerg Med 2022 Aug;63(2):e62-e65. Epub 2021 Oct 23 doi: 10.1016/j.jemermed.2021.10.005. PMID: 35690533Free PMC Article
A 16-Year-Old-Girl With Asthma, Palpable Purpura, and Hypereosinophilia.
Singh J, Randev S, Kumar P, Mahajan V, Aggarwal P, Sharma A, Guglani V
Chest 2022 May;161(5):e305-e308. doi: 10.1016/j.chest.2021.12.632. PMID: 35526901
Vancomycin-associated Henoch-Schönlein purpura.
Min Z, Garcia RR, Murillo M, Uchin JM, Bhanot N
J Infect Chemother 2017 Mar;23(3):180-184. Epub 2016 Sep 25 doi: 10.1016/j.jiac.2016.08.012. PMID: 27681233
Allergic vascular purpura.
Criep LH
J Allergy Clin Immunol 1971 Jul;48(1):7-12. doi: 10.1016/0091-6749(71)90049-2. PMID: 4996879

Prognosis

Rare manifestations of cryoglobulinemic vasculitis: a case report.
Leleux C, Zerbib Y, Pommerolle P, Da Rocha A, Serpier M, Caillard P
Front Immunol 2023;14:1271584. Epub 2023 Oct 13 doi: 10.3389/fimmu.2023.1271584. PMID: 37901234Free PMC Article
Cutaneous Involvement in Catastrophic Antiphospholipid Syndrome in a Multicenter Cohort of 65 Patients.
Dupré A, Morel N, Yelnik C, Moguelet P, Le Guern V, Stammler R, Nguyen Y, Paule R, Dufrost V, Ackermann F, Benhamou Y, Godeau B, Lambert M, Duffau P, Mekinian A, Saadoun D, Mouthon L, Hachulla E, Maillard H, Levesque H, Morell-Dubois S, Leroux G, Piette JC, Chasset F, Costedoat-Chalumeau N
JAMA Dermatol 2023 Jan 1;159(1):62-67. doi: 10.1001/jamadermatol.2022.5221. PMID: 36477813Free PMC Article
A Case of Leukocytoclastic Vasculitis Following SARS-COV-2 Vaccination.
Ball-Burack MR, Kosowsky JM
J Emerg Med 2022 Aug;63(2):e62-e65. Epub 2021 Oct 23 doi: 10.1016/j.jemermed.2021.10.005. PMID: 35690533Free PMC Article
Vasculitis-What Do We Have to Know? A Review of Literature.
Shavit E, Alavi A, Sibbald RG
Int J Low Extrem Wounds 2018 Dec;17(4):218-226. Epub 2018 Dec 3 doi: 10.1177/1534734618804982. PMID: 30501545
Schönlein-henoch purpura in children and adults: diagnosis, pathophysiology and management.
Rostoker G
BioDrugs 2001;15(2):99-138. doi: 10.2165/00063030-200115020-00004. PMID: 11437679

Clinical prediction guides

Torasemide-induced Vascular Purpura in the Course of Eosinophilic Granulomatosis with Polyangiitis.
Frątczak A, Polak K, Miziołek B, Bergler-Czop B
Acta Dermatovenerol Croat 2022 Sep;30(2):116-118. PMID: 36254546
Clinical association of mixed connective tissue disease and granulomatosis with polyangiitis: a case report and systematic screening of anti-U1RNP and anti-PR3 auto-antibody double positivity in ten European hospitals.
Tubery A, Fortenfant F, Combe B, Abreu I, Bossuyt X, Chretien P, Desplat-Jégo S, Fabien N, Hue S, Johanet C, Lakomy D, Vincent T, Daïen CI
Immunol Res 2016 Dec;64(5-6):1243-1246. doi: 10.1007/s12026-016-8861-3. PMID: 27618831
Multicentric Castleman's disease, non-Hodgkin's lymphoma, and Kaposi's sarcoma: a rare simultaneous occurrence.
Sukpanichnant S, Sivayathorn A, Visudhiphan S, Ngowthammatas W
Asian Pac J Allergy Immunol 2002 Jun;20(2):127-33. PMID: 12403198
Schönlein-henoch purpura in children and adults: diagnosis, pathophysiology and management.
Rostoker G
BioDrugs 2001;15(2):99-138. doi: 10.2165/00063030-200115020-00004. PMID: 11437679
IgA-IgG cryoglobulinaemia with vasculitis.
Whitsed HM, Penny R
Clin Exp Immunol 1971 Aug;9(2):183-91. PMID: 5315180Free PMC Article

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