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Skin pigmented basal cell carcinoma

MedGen UID:
237149
Concept ID:
C1368275
Neoplastic Process
Synonym: Carcinoma, Basal Cell, Pigmented
SNOMED CT: Pigmented basal cell carcinoma (399585007); Pigmented basal cell carcinoma (403909004)
 
Monarch Initiative: MONDO:0002939

Definition

A basal cell carcinoma that contains large amounts of melanin. The melanin is produced by symbiotic nontumoral proliferating melanocytes. [from NCI]

Professional guidelines

PubMed

Peris K, Fargnoli MC, Kaufmann R, Arenberger P, Bastholt L, Seguin NB, Bataille V, Brochez L, Del Marmol V, Dummer R, Forsea AM, Gaudy-Marqueste C, Harwood CA, Hauschild A, Höller C, Kandolf L, Kellerners-Smeets NWJ, Lallas A, Leiter U, Malvehy J, Marinović B, Mijuskovic Z, Moreno-Ramirez D, Nagore E, Nathan P, Stratigos AJ, Stockfleth E, Tagliaferri L, Trakatelli M, Vieira R, Zalaudek I, Garbe C; EADO”A, EDF”B, ESTRO”C, UEMS”D and EADV”E
Eur J Cancer 2023 Oct;192:113254. Epub 2023 Jul 28 doi: 10.1016/j.ejca.2023.113254. PMID: 37604067
Basset-Seguin N, Herms F
Acta Derm Venereol 2020 Jun 3;100(11):adv00140. doi: 10.2340/00015555-3495. PMID: 32346750Free PMC Article
Peris K, Fargnoli MC, Garbe C, Kaufmann R, Bastholt L, Seguin NB, Bataille V, Marmol VD, Dummer R, Harwood CA, Hauschild A, Höller C, Haedersdal M, Malvehy J, Middleton MR, Morton CA, Nagore E, Stratigos AJ, Szeimies RM, Tagliaferri L, Trakatelli M, Zalaudek I, Eggermont A, Grob JJ; European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organization for Research and Treatment of Cancer (EORTC)
Eur J Cancer 2019 Sep;118:10-34. Epub 2019 Jul 6 doi: 10.1016/j.ejca.2019.06.003. PMID: 31288208

Recent clinical studies

Etiology

Peris K, Fargnoli MC, Kaufmann R, Arenberger P, Bastholt L, Seguin NB, Bataille V, Brochez L, Del Marmol V, Dummer R, Forsea AM, Gaudy-Marqueste C, Harwood CA, Hauschild A, Höller C, Kandolf L, Kellerners-Smeets NWJ, Lallas A, Leiter U, Malvehy J, Marinović B, Mijuskovic Z, Moreno-Ramirez D, Nagore E, Nathan P, Stratigos AJ, Stockfleth E, Tagliaferri L, Trakatelli M, Vieira R, Zalaudek I, Garbe C; EADO”A, EDF”B, ESTRO”C, UEMS”D and EADV”E
Eur J Cancer 2023 Oct;192:113254. Epub 2023 Jul 28 doi: 10.1016/j.ejca.2023.113254. PMID: 37604067
Heath MS, Bar A
Dermatol Clin 2023 Jan;41(1):13-21. Epub 2022 Oct 28 doi: 10.1016/j.det.2022.07.005. PMID: 36410973
Basset-Seguin N, Herms F
Acta Derm Venereol 2020 Jun 3;100(11):adv00140. doi: 10.2340/00015555-3495. PMID: 32346750Free PMC Article
Kim DP, Kus KJB, Ruiz E
Hematol Oncol Clin North Am 2019 Feb;33(1):13-24. doi: 10.1016/j.hoc.2018.09.004. PMID: 30497670
Marzuka AG, Book SE
Yale J Biol Med 2015 Jun;88(2):167-79. Epub 2015 Jun 1 PMID: 26029015Free PMC Article

Diagnosis

Heath MS, Bar A
Dermatol Clin 2023 Jan;41(1):13-21. Epub 2022 Oct 28 doi: 10.1016/j.det.2022.07.005. PMID: 36410973
Álvarez-Salafranca M, Ara M, Zaballos P
Actas Dermosifiliogr (Engl Ed) 2021 Apr;112(4):330-338. Epub 2020 Nov 28 doi: 10.1016/j.ad.2020.11.011. PMID: 33259816
Tanese K
Curr Treat Options Oncol 2019 Feb 11;20(2):13. doi: 10.1007/s11864-019-0610-0. PMID: 30741348
Kim DP, Kus KJB, Ruiz E
Hematol Oncol Clin North Am 2019 Feb;33(1):13-24. doi: 10.1016/j.hoc.2018.09.004. PMID: 30497670
Weber P, Tschandl P, Sinz C, Kittler H
Curr Treat Options Oncol 2018 Sep 20;19(11):56. doi: 10.1007/s11864-018-0573-6. PMID: 30238167Free PMC Article

Therapy

Reiter O, Mimouni I, Dusza S, Halpern AC, Leshem YA, Marghoob AA
J Am Acad Dermatol 2021 Sep;85(3):653-664. Epub 2019 Nov 7 doi: 10.1016/j.jaad.2019.11.008. PMID: 31706938Free PMC Article
Thomson J, Hogan S, Leonardi-Bee J, Williams HC, Bath-Hextall FJ
Cochrane Database Syst Rev 2020 Nov 17;11(11):CD003412. doi: 10.1002/14651858.CD003412.pub3. PMID: 33202063Free PMC Article
Tanese K
Curr Treat Options Oncol 2019 Feb 11;20(2):13. doi: 10.1007/s11864-019-0610-0. PMID: 30741348
Cameron MC, Lee E, Hibler BP, Giordano CN, Barker CA, Mori S, Cordova M, Nehal KS, Rossi AM
J Am Acad Dermatol 2019 Feb;80(2):321-339. Epub 2018 May 19 doi: 10.1016/j.jaad.2018.02.083. PMID: 29782901
Marzuka AG, Book SE
Yale J Biol Med 2015 Jun;88(2):167-79. Epub 2015 Jun 1 PMID: 26029015Free PMC Article

Prognosis

Schmults CD, Blitzblau R, Aasi SZ, Alam M, Amini A, Bibee K, Bordeaux J, Chen PL, Contreras CM, DiMaio D, Donigan JM, Farma JM, Ghosh K, Harms K, Ho AL, Lukens JN, Mark L, Medina T, Nehal KS, Nghiem P, Olino K, Park S, Patel T, Puzanov I, Rich J, Sekulic A, Shaha AR, Srivastava D, Thomas V, Tomblinson C, Venkat P, Xu YG, Yu S, Yusuf M, McCullough B, Espinosa S
J Natl Compr Canc Netw 2023 Nov;21(11):1181-1203. doi: 10.6004/jnccn.2023.0056. PMID: 37935106
Álvarez-Salafranca M, Ara M, Zaballos P
Actas Dermosifiliogr (Engl Ed) 2021 Apr;112(4):330-338. Epub 2020 Nov 28 doi: 10.1016/j.ad.2020.11.011. PMID: 33259816
Tanese K
Curr Treat Options Oncol 2019 Feb 11;20(2):13. doi: 10.1007/s11864-019-0610-0. PMID: 30741348
Kim DP, Kus KJB, Ruiz E
Hematol Oncol Clin North Am 2019 Feb;33(1):13-24. doi: 10.1016/j.hoc.2018.09.004. PMID: 30497670
Cameron MC, Lee E, Hibler BP, Barker CA, Mori S, Cordova M, Nehal KS, Rossi AM
J Am Acad Dermatol 2019 Feb;80(2):303-317. Epub 2018 May 18 doi: 10.1016/j.jaad.2018.03.060. PMID: 29782900

Clinical prediction guides

Damsin T, Lebas E, Marchal N, Rorive A, Nikkels AF
Expert Rev Anticancer Ther 2022 Mar;22(3):243-248. Epub 2022 Feb 22 doi: 10.1080/14737140.2022.2043748. PMID: 35175882
Sharma P, Wadhwan V, Bansal V
Indian J Dent Res 2021 Jul-Sep;32(3):407-410. doi: 10.4103/ijdr.IJDR_227_19. PMID: 35229784
Álvarez-Salafranca M, Ara M, Zaballos P
Actas Dermosifiliogr (Engl Ed) 2021 Apr;112(4):330-338. Epub 2020 Nov 28 doi: 10.1016/j.ad.2020.11.011. PMID: 33259816
Peris K, Fargnoli MC, Garbe C, Kaufmann R, Bastholt L, Seguin NB, Bataille V, Marmol VD, Dummer R, Harwood CA, Hauschild A, Höller C, Haedersdal M, Malvehy J, Middleton MR, Morton CA, Nagore E, Stratigos AJ, Szeimies RM, Tagliaferri L, Trakatelli M, Zalaudek I, Eggermont A, Grob JJ; European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organization for Research and Treatment of Cancer (EORTC)
Eur J Cancer 2019 Sep;118:10-34. Epub 2019 Jul 6 doi: 10.1016/j.ejca.2019.06.003. PMID: 31288208
Cohen PR
Skinmed 2018;16(2):105-110. Epub 2018 Apr 1 PMID: 29911527

Recent systematic reviews

Jones OT, Matin RN, van der Schaar M, Prathivadi Bhayankaram K, Ranmuthu CKI, Islam MS, Behiyat D, Boscott R, Calanzani N, Emery J, Williams HC, Walter FM
Lancet Digit Health 2022 Jun;4(6):e466-e476. doi: 10.1016/S2589-7500(22)00023-1. PMID: 35623799
Reiter O, Mimouni I, Dusza S, Halpern AC, Leshem YA, Marghoob AA
J Am Acad Dermatol 2021 Sep;85(3):653-664. Epub 2019 Nov 7 doi: 10.1016/j.jaad.2019.11.008. PMID: 31706938Free PMC Article
Thomson J, Hogan S, Leonardi-Bee J, Williams HC, Bath-Hextall FJ
Cochrane Database Syst Rev 2020 Nov 17;11(11):CD003412. doi: 10.1002/14651858.CD003412.pub3. PMID: 33202063Free PMC Article
Zaorsky NG, Lee CT, Zhang E, Keith SW, Galloway TJ
Radiother Oncol 2017 Oct;125(1):13-20. Epub 2017 Aug 23 doi: 10.1016/j.radonc.2017.08.011. PMID: 28843727Free PMC Article
Lomas A, Leonardi-Bee J, Bath-Hextall F
Br J Dermatol 2012 May;166(5):1069-80. doi: 10.1111/j.1365-2133.2012.10830.x. PMID: 22251204

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