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Cutaneous candidiasis

MedGen UID:
2427
•Concept ID:
C0006846
•
Disease or Syndrome
Synonyms: Candidiasis, Cutaneous; Moniliasis, Cutaneous
SNOMED CT: Candidosis of skin (49883006); Candida of skin (49883006); Candidiasis of skin (49883006)
 
Monarch Initiative: MONDO:0000879

Definition

Candidiasis of the skin manifested as eczema-like lesions of the interdigital spaces, perleche, or chronic paronychia. (Dorland, 27th ed) [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCutaneous candidiasis

Professional guidelines

PubMed

The diagnosis, management and prevention of intertrigo in adults: a review.
Romanelli M, Voegeli D, Colboc H, Bassetto F, Janowska A, Scarpa C, Meaume S
J Wound Care 2023 Jul 2;32(7):411-420. doi: 10.12968/jowc.2023.32.7.411. PMID: 37405940
Mycological Considerations in the Topical Treatment of Superficial Fungal Infections.
Rosen T
J Drugs Dermatol 2016 Feb;15(2 Suppl):s49-55. PMID: 26885799
Pustular skin disorders: diagnosis and treatment.
Mengesha YM, Bennett ML
Am J Clin Dermatol 2002;3(6):389-400. doi: 10.2165/00128071-200203060-00003. PMID: 12113648

Recent clinical studies

Etiology

Cutaneous candidiasis - an evidence-based review of topical and systemic treatments to inform clinical practice.
Taudorf EH, Jemec GBE, Hay RJ, Saunte DML
J Eur Acad Dermatol Venereol 2019 Oct;33(10):1863-1873. Epub 2019 Jul 30 doi: 10.1111/jdv.15782. PMID: 31287594
Angioinvasive fungal infections impacting the skin: Background, epidemiology, and clinical presentation.
Shields BE, Rosenbach M, Brown-Joel Z, Berger AP, Ford BA, Wanat KA
J Am Acad Dermatol 2019 Apr;80(4):869-880.e5. Epub 2018 Aug 10 doi: 10.1016/j.jaad.2018.04.059. PMID: 30102951
Erosio interdigitalis blastomycetica: A review of interdigital candidiasis.
Schlager E, Ashack K, Khachemoune A
Dermatol Online J 2018 Aug 15;24(8) PMID: 30677843
Incontinence-associated dermatitis: a comprehensive review and update.
Gray M, Beeckman D, Bliss DZ, Fader M, Logan S, Junkin J, Selekof J, Doughty D, Kurz P
J Wound Ostomy Continence Nurs 2012 Jan-Feb;39(1):61-74. doi: 10.1097/WON.0b013e31823fe246. PMID: 22193141
Cutaneous mycoses in children.
Elewski BE
Br J Dermatol 1996 Jun;134 Suppl 46:7-11: discussion 37-8. doi: 10.1111/j.1365-2133.1996.tb15651.x. PMID: 8763460

Diagnosis

The diagnosis, management and prevention of intertrigo in adults: a review.
Romanelli M, Voegeli D, Colboc H, Bassetto F, Janowska A, Scarpa C, Meaume S
J Wound Care 2023 Jul 2;32(7):411-420. doi: 10.12968/jowc.2023.32.7.411. PMID: 37405940
Congenital Cutaneous Candidiasis in Preterm Infants.
Shope C, Ritter A, Karlin S, Lee LW, Cotton CH
Neoreviews 2023 Mar 1;24(3):e175-e180. doi: 10.1542/neo.24-3-e175. PMID: 36854848
Common Child and Adolescent Cutaneous Infestations and Fungal Infections.
Alter SJ, McDonald MB, Schloemer J, Simon R, Trevino J
Curr Probl Pediatr Adolesc Health Care 2018 Jan;48(1):3-25. Epub 2017 Dec 6 doi: 10.1016/j.cppeds.2017.11.001. PMID: 29198783
Fungal skin disorders.
Rupke SJ
Prim Care 2000 Jun;27(2):407-21. doi: 10.1016/s0095-4543(05)70203-7. PMID: 10815051
Candidiasis--serology and diagnosis.
COMAISH JS, GIBSON B, GREEN CA
J Invest Dermatol 1963 Mar;40:139-42. PMID: 14022471

Therapy

Candidiasis: From cutaneous to systemic, new perspectives of potential targets and therapeutic strategies.
Lu H, Hong T, Jiang Y, Whiteway M, Zhang S
Adv Drug Deliv Rev 2023 Aug;199:114960. Epub 2023 Jun 10 doi: 10.1016/j.addr.2023.114960. PMID: 37307922
Cutaneous candidiasis - an evidence-based review of topical and systemic treatments to inform clinical practice.
Taudorf EH, Jemec GBE, Hay RJ, Saunte DML
J Eur Acad Dermatol Venereol 2019 Oct;33(10):1863-1873. Epub 2019 Jul 30 doi: 10.1111/jdv.15782. PMID: 31287594
Naftifine: a review.
Gupta AK, Ryder JE, Cooper EA
J Cutan Med Surg 2008 Mar-Apr;12(2):51-8. doi: 10.2310/7750.2008.06009. PMID: 18346400
Six novel antimycotics.
Rubin AI, Bagheri B, Scher RK
Am J Clin Dermatol 2002;3(2):71-81. doi: 10.2165/00128071-200203020-00001. PMID: 11893219
Nystatin.
Witten VH, Katz SI
Med Clin North Am 1970 Sep;54(5):1329-37. PMID: 4919155

Prognosis

Erosio interdigitalis blastomycetica: A review of interdigital candidiasis.
Schlager E, Ashack K, Khachemoune A
Dermatol Online J 2018 Aug 15;24(8) PMID: 30677843
Primary immunodeficiency update: Part II. Syndromes associated with mucocutaneous candidiasis and noninfectious cutaneous manifestations.
Pichard DC, Freeman AF, Cowen EW
J Am Acad Dermatol 2015 Sep;73(3):367-81; quiz 381-2. doi: 10.1016/j.jaad.2015.01.055. PMID: 26282795Free PMC Article
Ciclopirox (Loprox) gel for superficial fungal infections.
Gupta AK, Bluhm R
Skin Therapy Lett 2004 Aug-Sep;9(7):4-5, 9. PMID: 15334276
Fungal skin disorders.
Rupke SJ
Prim Care 2000 Jun;27(2):407-21. doi: 10.1016/s0095-4543(05)70203-7. PMID: 10815051
Cutaneous and mucosal manifestations of the deep mycotic infections.
Meyer RD
Acta Derm Venereol Suppl (Stockh) 1986;121:57-72. PMID: 3521177

Clinical prediction guides

Prevalence and Clinical Correlation of Superficial Fungal Foot Infection in Thai Naval Rating Cadets.
Ongsri P, Bunyaratavej S, Leeyaphan C, Pattanaprichakul P, Ongmahutmongkol P, Komoltri C, Kulthanan K
Mil Med 2018 Sep 1;183(9-10):e633-e637. doi: 10.1093/milmed/usx187. PMID: 29447400
Skin interaction with absorbent hygiene products.
Runeman B
Clin Dermatol 2008 Jan-Feb;26(1):45-51. doi: 10.1016/j.clindermatol.2007.10.002. PMID: 18280904
Cutaneous manifestations of candidiasis.
McKay M
Am J Obstet Gynecol 1988 Apr;158(4):991-3. doi: 10.1016/0002-9378(88)90110-x. PMID: 3364512
Cutaneous and mucosal manifestations of the deep mycotic infections.
Meyer RD
Acta Derm Venereol Suppl (Stockh) 1986;121:57-72. PMID: 3521177
Congenital cutaneous candidiasis.
Rudolph N, Tariq AA, Reale MR, Goldberg PK, Kozinn PJ
Arch Dermatol 1977 Aug;113(8):1101-3. PMID: 889338

Recent systematic reviews

Vulvovaginal candidiasis in Iran: A systematic review and meta-analysis on the epidemiology, clinical manifestations, demographic characteristics, risk factors, etiologic agents and laboratory diagnosis.
Sasani E, Rafat Z, Ashrafi K, Salimi Y, Zandi M, Soltani S, Hashemi F, Hashemi SJ
Microb Pathog 2021 May;154:104802. Epub 2021 Mar 16 doi: 10.1016/j.micpath.2021.104802. PMID: 33741400
Novel use of terpenoids for treatment of dermatologic diseases: a systematic review of clinical trials.
Tuong W, Walker L, Sivamani RK
J Altern Complement Med 2015 May;21(5):261-8. Epub 2015 Apr 29 doi: 10.1089/acm.2014.0273. PMID: 25923990
Efficacy of topical antifungal drugs in different dermatomycoses: a systematic review with meta-analysis.
Rotta I, Otuki MF, Sanches AC, Correr CJ
Rev Assoc Med Bras (1992) 2012 May-Jun;58(3):308-18. PMID: 22735222

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