U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Central auditory dysfunction

MedGen UID:
2492
•Concept ID:
C0004303
•
Disease or Syndrome
Synonyms: Auditory Disease, Central; Auditory Diseases, Central; Auditory Dysfunction, Central; Auditory Pathway Disorders, Central; Central Auditory Disease; Central Auditory Diseases; Central Auditory Dysfunction; Central Auditory Pathway Disorders; Dysfunction, Central Auditory; Dysfunctions, Central Auditory
SNOMED CT: Central auditory dysfunction (68467004)

Definition

Disorders of hearing or auditory perception due to pathological processes of the AUDITORY PATHWAYS in the CENTRAL NERVOUS SYSTEM. These include CENTRAL HEARING LOSS and AUDITORY PERCEPTUAL DISORDERS. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral auditory dysfunction

Professional guidelines

PubMed

The natural history, clinical outcomes, and genotype-phenotype relationship of otoferlin-related hearing loss: a systematic, quantitative literature review.
Ford CL, Riggs WJ, Quigley T, Keifer OP Jr, Whitton JP, Valayannopoulos V
Hum Genet 2023 Oct;142(10):1429-1449. Epub 2023 Sep 7 doi: 10.1007/s00439-023-02595-5. PMID: 37679651Free PMC Article
Advances in Understanding, Diagnosis, and Treatment of Tinnitus.
Tang D, Li H, Chen L
Adv Exp Med Biol 2019;1130:109-128. doi: 10.1007/978-981-13-6123-4_7. PMID: 30915704
Learning and cognitive disorders: multidiscipline treatment approaches.
Chacko A, Uderman J, Feirsen N, Bedard AC, Marks D
Child Adolesc Psychiatr Clin N Am 2013 Jul;22(3):457-77, vi. Epub 2013 May 17 doi: 10.1016/j.chc.2013.03.006. PMID: 23806314Free PMC Article

Recent clinical studies

Etiology

Evaluation of auditory system in obstructive sleep apnea patients.
Lim CC, Ahmad TEBTN, Sawali HB, Afandi ANB, Paniselvam V, Bernard MW, Narayanan P, Bakar MZBA
Eur Arch Otorhinolaryngol 2023 May;280(5):2201-2207. Epub 2022 Nov 9 doi: 10.1007/s00405-022-07711-1. PMID: 36350365Free PMC Article
Hearing loss and Alzheimer's disease: A Review.
Ralli M, Gilardi A, Stadio AD, Severini C, Salzano FA, Greco A, Vincentiis M
Int Tinnitus J 2019 Sep 4;23(2):79-85. doi: 10.5935/0946-5448.20190014. PMID: 32009339
Auditory system dysfunction in Alzheimer disease and its prodromal states: A review.
Swords GM, Nguyen LT, Mudar RA, Llano DA
Ageing Res Rev 2018 Jul;44:49-59. Epub 2018 Apr 6 doi: 10.1016/j.arr.2018.04.001. PMID: 29630950Free PMC Article
Implications of blast exposure for central auditory function: a review.
Gallun FJ, Lewis MS, Folmer RL, Diedesch AC, Kubli LR, McDermott DJ, Walden TC, Fausti SA, Lew HL, Leek MR
J Rehabil Res Dev 2012;49(7):1059-74. doi: 10.1682/jrrd.2010.09.0166. PMID: 23341279
Auditory brainstem potentials in uraemia.
Küstel M, Büki B, Gyimesi J, Makó J, Komora V, Ribári O
ORL J Otorhinolaryngol Relat Spec 1993 Mar-Apr;55(2):89-92. doi: 10.1159/000276387. PMID: 8446393

Diagnosis

Auditory brainstem response audiometry in tauopathy mouse model of human Alzheimer's disease.
Burke K, Screven LA, Vicencio-Jimenez S, Lauer AM
JASA Express Lett 2024 Jul 1;4(7) doi: 10.1121/10.0026602. PMID: 38980136Free PMC Article
Is there an association between noise exposure and King Kopetzky Syndrome?
Stephens D, Zhao F, Kennedy V
Noise Health 2003 Jul-Sep;5(20):55-62. PMID: 14558893
Electrophysiologic and behavioral auditory findings in multiple sclerosis.
Musiek FE, Gollegly KM, Kibbe KS, Reeves AG
Am J Otol 1989 Sep;10(5):343-50. PMID: 2817103
Learning disability assessed through audiologic and physiologic measures: a case study.
Greenblatt ER, Bar A, Zappulla RA
J Commun Disord 1983 Sep;16(5):309-13. doi: 10.1016/0021-9924(83)90015-1. PMID: 6668361
Normal audiometric findings.
Jerger J, Jordan C
Am J Otol 1980 Jan;1(3):157-9. PMID: 7457578

Therapy

The Adverse Effects of Heavy Metals with and without Noise Exposure on the Human Peripheral and Central Auditory System: A Literature Review.
Castellanos MJ, Fuente A
Int J Environ Res Public Health 2016 Dec 9;13(12) doi: 10.3390/ijerph13121223. PMID: 27941700Free PMC Article
Central auditory dysfunction associated with exposure to a mixture of solvents.
Fuente A, McPherson B, Hickson L
Int J Audiol 2011 Dec;50(12):857-65. Epub 2011 Sep 22 doi: 10.3109/14992027.2011.605805. PMID: 21936752
Peripheral and central auditory dysfunction induced by occupational exposure to organic solvents.
Fuente A, Slade MD, Taylor T, Morata TC, Keith RW, Sparer J, Rabinowitz PM
J Occup Environ Med 2009 Oct;51(10):1202-11. doi: 10.1097/JOM.0b013e3181bae17c. PMID: 19786896
Is there an association between noise exposure and King Kopetzky Syndrome?
Stephens D, Zhao F, Kennedy V
Noise Health 2003 Jul-Sep;5(20):55-62. PMID: 14558893
Dichotic speech tests.
Hällgren M, Johansson M, Larsby B, Arlinger S
Scand Audiol Suppl 1998;49:35-9. doi: 10.1080/010503998420630. PMID: 10209775

Prognosis

Evaluation of auditory system in obstructive sleep apnea patients.
Lim CC, Ahmad TEBTN, Sawali HB, Afandi ANB, Paniselvam V, Bernard MW, Narayanan P, Bakar MZBA
Eur Arch Otorhinolaryngol 2023 May;280(5):2201-2207. Epub 2022 Nov 9 doi: 10.1007/s00405-022-07711-1. PMID: 36350365Free PMC Article
Central auditory function of deafness genes.
Willaredt MA, Ebbers L, Nothwang HG
Hear Res 2014 Jun;312:9-20. Epub 2014 Feb 22 doi: 10.1016/j.heares.2014.02.004. PMID: 24566090
Implications of blast exposure for central auditory function: a review.
Gallun FJ, Lewis MS, Folmer RL, Diedesch AC, Kubli LR, McDermott DJ, Walden TC, Fausti SA, Lew HL, Leek MR
J Rehabil Res Dev 2012;49(7):1059-74. doi: 10.1682/jrrd.2010.09.0166. PMID: 23341279
Neural network modeling of central auditory dysfunction in Alzheimer's disease.
Krishnamurti S, Drake L, King J
Neural Netw 2011 Aug;24(6):646-51. Epub 2011 Mar 5 doi: 10.1016/j.neunet.2011.02.010. PMID: 21441013
The mismatch negativity in evaluating central auditory dysfunction in dyslexia.
Kujala T, Näätänen R
Neurosci Biobehav Rev 2001 Aug;25(6):535-43. doi: 10.1016/s0149-7634(01)00032-x. PMID: 11595273

Clinical prediction guides

Evaluation of auditory system in obstructive sleep apnea patients.
Lim CC, Ahmad TEBTN, Sawali HB, Afandi ANB, Paniselvam V, Bernard MW, Narayanan P, Bakar MZBA
Eur Arch Otorhinolaryngol 2023 May;280(5):2201-2207. Epub 2022 Nov 9 doi: 10.1007/s00405-022-07711-1. PMID: 36350365Free PMC Article
Auditory Agnosia for Environmental Sounds in Alzheimer's Disease: Not Hearing and Not Listening?
Coebergh JAF, McDowell S, van Woerkom TCAM, Koopman JP, Mulder J, Bruijn SFTM
J Alzheimers Dis 2020;73(4):1407-1419. doi: 10.3233/JAD-190431. PMID: 31958091
Central auditory function of deafness genes.
Willaredt MA, Ebbers L, Nothwang HG
Hear Res 2014 Jun;312:9-20. Epub 2014 Feb 22 doi: 10.1016/j.heares.2014.02.004. PMID: 24566090
Implications of blast exposure for central auditory function: a review.
Gallun FJ, Lewis MS, Folmer RL, Diedesch AC, Kubli LR, McDermott DJ, Walden TC, Fausti SA, Lew HL, Leek MR
J Rehabil Res Dev 2012;49(7):1059-74. doi: 10.1682/jrrd.2010.09.0166. PMID: 23341279
Lead and lag effects associated with the staggered spondaic word test.
Freeman BA, Beasley DS
J Speech Hear Res 1976 Sep;19(3):572-7. doi: 10.1044/jshr.1903.572. PMID: 979218

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...