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Persistent flow of blood into aneurysm sac following endovascular insertion of stent graft

MedGen UID:
264185
•Concept ID:
C1504464
•
Pathologic Function
Synonyms: Endoleak; Endoleaks; Leak, Perigraft; Perigraft Leak; Perigraft Leaks
SNOMED CT: Endoleak (1208762007); Persistent flow of blood into aneurysm sac following endovascular insertion of stent graft (1208762007)

Definition

Persistent blood flow/pressure in the aneurysm sac following an endovascular aneurysm repair (EVAR) procedure. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPersistent flow of blood into aneurysm sac following endovascular insertion of stent graft

Professional guidelines

PubMed

Management of Postoperative Complications Following Endovascular Aortic Aneurysm Repair.
Qrareya M, Zuhaili B
Surg Clin North Am 2021 Oct;101(5):785-798. Epub 2021 Jul 30 doi: 10.1016/j.suc.2021.05.020. PMID: 34537143
Society for Vascular Surgery clinical practice guidelines of thoracic endovascular aortic repair for descending thoracic aortic aneurysms.
Upchurch GR Jr, Escobar GA, Azizzadeh A, Beck AW, Conrad MF, Matsumura JS, Murad MH, Perry RJ, Singh MJ, Veeraswamy RK, Wang GJ
J Vasc Surg 2021 Jan;73(1S):55S-83S. Epub 2020 Jul 3 doi: 10.1016/j.jvs.2020.05.076. PMID: 32628988
The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm.
Chaikof EL, Dalman RL, Eskandari MK, Jackson BM, Lee WA, Mansour MA, Mastracci TM, Mell M, Murad MH, Nguyen LL, Oderich GS, Patel MS, Schermerhorn ML, Starnes BW
J Vasc Surg 2018 Jan;67(1):2-77.e2. doi: 10.1016/j.jvs.2017.10.044. PMID: 29268916

Recent clinical studies

Etiology

Imaging modalities for endoleak surveillance.
Williams AB, Williams ZB
J Med Radiat Sci 2021 Dec;68(4):446-452. Epub 2021 Jun 18 doi: 10.1002/jmrs.522. PMID: 34145780Free PMC Article
Open and Endovascular Management of Aortic Aneurysms.
Swerdlow NJ, Wu WW, Schermerhorn ML
Circ Res 2019 Feb 15;124(4):647-661. doi: 10.1161/CIRCRESAHA.118.313186. PMID: 30763206
Type II endoleaks: when and how.
Grima MJ, Karthikesalingam A
J Cardiovasc Surg (Torino) 2017 Dec;58(6):889-894. Epub 2017 Jun 19 doi: 10.23736/S0021-9509.17.10072-8. PMID: 28627864
Aneurysm Sac Enlargement after Endovascular Abdominal Aortic Aneurysm Repair.
Dingemans SA, Jonker FH, Moll FL, van Herwaarden JA
Ann Vasc Surg 2016 Feb;31:229-38. Epub 2015 Nov 25 doi: 10.1016/j.avsg.2015.08.011. PMID: 26627324
Type II endoleaks.
Avgerinos ED, Chaer RA, Makaroun MS
J Vasc Surg 2014 Nov;60(5):1386-1391. Epub 2014 Aug 28 doi: 10.1016/j.jvs.2014.07.100. PMID: 25175637

Diagnosis

Imaging modalities for endoleak surveillance.
Williams AB, Williams ZB
J Med Radiat Sci 2021 Dec;68(4):446-452. Epub 2021 Jun 18 doi: 10.1002/jmrs.522. PMID: 34145780Free PMC Article
Society for Vascular Surgery clinical practice guidelines of thoracic endovascular aortic repair for descending thoracic aortic aneurysms.
Upchurch GR Jr, Escobar GA, Azizzadeh A, Beck AW, Conrad MF, Matsumura JS, Murad MH, Perry RJ, Singh MJ, Veeraswamy RK, Wang GJ
J Vasc Surg 2021 Jan;73(1S):55S-83S. Epub 2020 Jul 3 doi: 10.1016/j.jvs.2020.05.076. PMID: 32628988
Type II endoleaks: when and how.
Grima MJ, Karthikesalingam A
J Cardiovasc Surg (Torino) 2017 Dec;58(6):889-894. Epub 2017 Jun 19 doi: 10.23736/S0021-9509.17.10072-8. PMID: 28627864
MDCT of endoleaks following endovascular repair of abdominal aortic aneurysms.
Heller MT, Shah AB, Bhargava P, Srivastava U, Sun X
Clin Imaging 2015 May-Jun;39(3):367-73. Epub 2015 Jan 14 doi: 10.1016/j.clinimag.2015.01.004. PMID: 25660322
Type II endoleaks.
Avgerinos ED, Chaer RA, Makaroun MS
J Vasc Surg 2014 Nov;60(5):1386-1391. Epub 2014 Aug 28 doi: 10.1016/j.jvs.2014.07.100. PMID: 25175637

Therapy

Imaging modalities for endoleak surveillance.
Williams AB, Williams ZB
J Med Radiat Sci 2021 Dec;68(4):446-452. Epub 2021 Jun 18 doi: 10.1002/jmrs.522. PMID: 34145780Free PMC Article
Open and Endovascular Management of Aortic Aneurysms.
Swerdlow NJ, Wu WW, Schermerhorn ML
Circ Res 2019 Feb 15;124(4):647-661. doi: 10.1161/CIRCRESAHA.118.313186. PMID: 30763206
Type II endoleaks: when and how.
Grima MJ, Karthikesalingam A
J Cardiovasc Surg (Torino) 2017 Dec;58(6):889-894. Epub 2017 Jun 19 doi: 10.23736/S0021-9509.17.10072-8. PMID: 28627864
Aneurysm Sac Enlargement after Endovascular Abdominal Aortic Aneurysm Repair.
Dingemans SA, Jonker FH, Moll FL, van Herwaarden JA
Ann Vasc Surg 2016 Feb;31:229-38. Epub 2015 Nov 25 doi: 10.1016/j.avsg.2015.08.011. PMID: 26627324
Type II endoleaks.
Avgerinos ED, Chaer RA, Makaroun MS
J Vasc Surg 2014 Nov;60(5):1386-1391. Epub 2014 Aug 28 doi: 10.1016/j.jvs.2014.07.100. PMID: 25175637

Prognosis

Predictors of sac regression after fenestrated endovascular aneurysm repair.
Li M, Stern JR, Tran K, Deslarzes-Dubuis C, Lee JT
J Vasc Surg 2022 Feb;75(2):433-438. Epub 2021 Sep 8 doi: 10.1016/j.jvs.2021.08.067. PMID: 34506890
Type II endoleaks: when and how.
Grima MJ, Karthikesalingam A
J Cardiovasc Surg (Torino) 2017 Dec;58(6):889-894. Epub 2017 Jun 19 doi: 10.23736/S0021-9509.17.10072-8. PMID: 28627864
Endovascular aneurysm sealing addresses several limitations of conventional endovascular aneurysm repair.
Kostun ZW, Woo EY
Semin Vasc Surg 2016 Mar;29(1-2):50-54. Epub 2016 Jun 18 doi: 10.1053/j.semvascsurg.2016.06.004. PMID: 27823590
Aortic stent-grafts: Endoleak surveillance.
Cassagnes L, Pérignon R, Amokrane F, Petermann A, Bécaud T, Saint-Lebes B, Chabrot P, Rousseau H, Boyer L
Diagn Interv Imaging 2016 Jan;97(1):19-27. Epub 2015 Aug 5 doi: 10.1016/j.diii.2014.12.014. PMID: 26254711
Type II endoleaks.
Avgerinos ED, Chaer RA, Makaroun MS
J Vasc Surg 2014 Nov;60(5):1386-1391. Epub 2014 Aug 28 doi: 10.1016/j.jvs.2014.07.100. PMID: 25175637

Clinical prediction guides

Predictors of sac regression after fenestrated endovascular aneurysm repair.
Li M, Stern JR, Tran K, Deslarzes-Dubuis C, Lee JT
J Vasc Surg 2022 Feb;75(2):433-438. Epub 2021 Sep 8 doi: 10.1016/j.jvs.2021.08.067. PMID: 34506890
Imaging modalities for endoleak surveillance.
Williams AB, Williams ZB
J Med Radiat Sci 2021 Dec;68(4):446-452. Epub 2021 Jun 18 doi: 10.1002/jmrs.522. PMID: 34145780Free PMC Article
Late Open Conversion Following Failure of EVAR and TEVAR: "State of the Art".
Rinaldi E, Kahlberg A, Carta N, Mascia D, Bertoglio L, Chiesa R
Cardiovasc Intervent Radiol 2020 Dec;43(12):1855-1864. Epub 2020 Aug 31 doi: 10.1007/s00270-020-02636-w. PMID: 32869159
Type II endoleaks: when and how.
Grima MJ, Karthikesalingam A
J Cardiovasc Surg (Torino) 2017 Dec;58(6):889-894. Epub 2017 Jun 19 doi: 10.23736/S0021-9509.17.10072-8. PMID: 28627864
Type II endoleaks.
Avgerinos ED, Chaer RA, Makaroun MS
J Vasc Surg 2014 Nov;60(5):1386-1391. Epub 2014 Aug 28 doi: 10.1016/j.jvs.2014.07.100. PMID: 25175637

Recent systematic reviews

A Meta-Analysis of Mid-Term Outcomes of Endovascular Aneurysm Sealing.
Kouvelos G, Nana P, Brodis A, Spanos K, Tasoudis P, Katsargyris A, Verhoeven E
J Endovasc Ther 2023 Oct;30(5):664-675. Epub 2022 Jun 8 doi: 10.1177/15266028221098706. PMID: 35674455
A systematic review of primary endovascular repair of the ascending aorta.
Muetterties CE, Menon R, Wheatley GH 3rd
J Vasc Surg 2018 Jan;67(1):332-342. Epub 2017 Aug 23 doi: 10.1016/j.jvs.2017.06.099. PMID: 28844469
A systematic review of surveillance after endovascular aortic repair.
Zaiem F, Almasri J, Tello M, Prokop LJ, Chaikof EL, Murad MH
J Vasc Surg 2018 Jan;67(1):320-331.e37. Epub 2017 Jun 26 doi: 10.1016/j.jvs.2017.04.058. PMID: 28662928
Outcomes of Endovascular Abdominal Aortic Aneurysm Repair in Octogenarians: Meta-analysis and Systematic Review.
Han Y, Zhang S, Zhang J, Ji C, Eckstein HH
Eur J Vasc Endovasc Surg 2017 Oct;54(4):454-463. Epub 2017 Aug 16 doi: 10.1016/j.ejvs.2017.06.027. PMID: 28822680
Endovascular abdominal aortic aneurysm sealing: A systematic review of early outcomes.
Brown SL, Awopetu A, Delbridge MS, Stather PW
Vascular 2017 Aug;25(4):423-429. Epub 2016 Dec 14 doi: 10.1177/1708538116684941. PMID: 28264179

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