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Minimally Invasive Lung Mucinous Adenocarcinoma

MedGen UID:
266090
•Concept ID:
C1266035
•
Neoplastic Process
Synonym: Mucinous Minimally Invasive Lung Adenocarcinoma

Definition

A morphologic variant of minimally invasive lung adenocarcinoma characterized by tall columnar cells and mucin production. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMinimally Invasive Lung Mucinous Adenocarcinoma

Recent clinical studies

Etiology

Validation Study of New IASLC Histology Grading System in Stage I Non-Mucinous Adenocarcinoma Comparing With Minimally Invasive Adenocarcinoma.
Woo W, Cha YJ, Kim BJ, Moon DH, Lee S
Clin Lung Cancer 2022 Nov;23(7):e435-e442. Epub 2022 Jun 22 doi: 10.1016/j.cllc.2022.06.004. PMID: 35945128
Solid histological component of adenocarcinoma might play an important role in PD-L1 expression of lung adenocarcinoma.
Miyazawa T, Morikawa K, Otsubo K, Sakai H, Kimura H, Chosokabe M, Furuya N, Marushima H, Kojima K, Mineshita M, Koike J, Saji H
Thorac Cancer 2022 Jan;13(1):24-30. Epub 2021 Nov 23 doi: 10.1111/1759-7714.14209. PMID: 34811933Free PMC Article
Comprehensive analysis of the clinicopathological features, targetable profile, and prognosis of mucinous adenocarcinoma of the lung.
Ueda D, Ito M, Tsutani Y, Giménez-Capitán A, Román-Lladó R, Pérez-Rosado A, Aguado C, Kushitani K, Miyata Y, Arihiro K, Molina-Vila MA, Rosell R, Takeshima Y, Okada M
J Cancer Res Clin Oncol 2021 Dec;147(12):3709-3718. Epub 2021 Apr 1 doi: 10.1007/s00432-021-03609-3. PMID: 33796913
Distinctive clinicopathological features of adenocarcinoma in situ and minimally invasive adenocarcinoma of the lung: A retrospective study.
Ishida H, Shimizu Y, Sakaguchi H, Nitanda H, Kaneko K, Yamazaki N, Yanagihara A, Taguchi R, Sakai F, Yasuda M, Kobayashi K
Lung Cancer 2019 Mar;129:16-21. Epub 2018 Dec 19 doi: 10.1016/j.lungcan.2018.12.020. PMID: 30797486
Increased risk of recurrence in resected EGFR-positive pN0M0 invasive lung adenocarcinoma.
Ito M, Miyata Y, Kushitani K, Yoshiya T, Kai Y, Tsutani Y, Mimura T, Konishi K, Takeshima Y, Okada M
Thorac Cancer 2018 Dec;9(12):1594-1602. Epub 2018 Oct 8 doi: 10.1111/1759-7714.12866. PMID: 30298562Free PMC Article

Diagnosis

Adenocarcinoma classification: patterns and prognosis.
Kuhn E, Morbini P, Cancellieri A, Damiani S, Cavazza A, Comin CE
Pathologica 2018 Mar;110(1):5-11. PMID: 30259909
The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the Forthcoming Eighth Edition of the TNM Classification of Lung Cancer.
Travis WD, Asamura H, Bankier AA, Beasley MB, Detterbeck F, Flieder DB, Goo JM, MacMahon H, Naidich D, Nicholson AG, Powell CA, Prokop M, Rami-Porta R, Rusch V, van Schil P, Yatabe Y; International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee and Advisory Board Members
J Thorac Oncol 2016 Aug;11(8):1204-1223. Epub 2016 Apr 21 doi: 10.1016/j.jtho.2016.03.025. PMID: 27107787
Current readings: pathology, prognosis, and lung cancer.
Suh JH
Semin Thorac Cardiovasc Surg 2013 Spring;25(1):14-21. doi: 10.1053/j.semtcvs.2013.01.003. PMID: 23800525
New pathologic classification of lung cancer: relevance for clinical practice and clinical trials.
Travis WD, Brambilla E, Riely GJ
J Clin Oncol 2013 Mar 10;31(8):992-1001. Epub 2013 Feb 11 doi: 10.1200/JCO.2012.46.9270. PMID: 23401443
International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.
Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE, Garg K, Austin JH, Asamura H, Rusch VW, Hirsch FR, Scagliotti G, Mitsudomi T, Huber RM, Ishikawa Y, Jett J, Sanchez-Cespedes M, Sculier JP, Takahashi T, Tsuboi M, Vansteenkiste J, Wistuba I, Yang PC, Aberle D, Brambilla C, Flieder D, Franklin W, Gazdar A, Gould M, Hasleton P, Henderson D, Johnson B, Johnson D, Kerr K, Kuriyama K, Lee JS, Miller VA, Petersen I, Roggli V, Rosell R, Saijo N, Thunnissen E, Tsao M, Yankelewitz D
J Thorac Oncol 2011 Feb;6(2):244-85. doi: 10.1097/JTO.0b013e318206a221. PMID: 21252716Free PMC Article

Therapy

Identification of a novel RSRC1-ALK (R6: A20) fusion using next-generation sequencing technique.
Xia J, Chen S, Zhang Z, Wang J
Cancer Genet 2023 Nov;278-279:18-23. Epub 2023 Aug 9 doi: 10.1016/j.cancergen.2023.08.003. PMID: 37572583
Is (99m) Tc bone scintigraphy necessary in the preoperative workup for patients with cT1N0 subsolid lung cancer? A prospective multicenter cohort study.
Li H, Ye T, Li N, Xia G, Li B, Zhang Y, Hu H, Sun Y, Zhang Y, Xiang J, Ma D, Weng Y, Liu S, Jia C, Qian B, Gu Y, Li Y, Song S, Chen H
Thorac Cancer 2021 Feb;12(4):415-419. Epub 2020 Nov 19 doi: 10.1111/1759-7714.13752. PMID: 33210466Free PMC Article
Clinical characteristics of patients with bronchioloalveolar carcinoma: a retrospective study of 44 cases.
Dirican N, Baysak A, Cok G, Goksel T, Aysan T
Asian Pac J Cancer Prev 2013;14(7):4365-8. doi: 10.7314/apjcp.2013.14.7.4365. PMID: 23992004
New pathologic classification of lung cancer: relevance for clinical practice and clinical trials.
Travis WD, Brambilla E, Riely GJ
J Clin Oncol 2013 Mar 10;31(8):992-1001. Epub 2013 Feb 11 doi: 10.1200/JCO.2012.46.9270. PMID: 23401443
Bronchoalveolar carcinoma of lung masquerading as iodine avid metastasis in a patient with minimally invasive follicular carcinoma of thyroid.
Malhotra G, Nair N, Menon H, Gujral S, Abhyankar A, Baghel NS, Awasare S, Nabar SJ, Abhyankar S, Kand PG
Clin Nucl Med 2008 Jan;33(1):26-9. doi: 10.1097/RLU.0b013e31815c50a8. PMID: 18097252

Prognosis

Adenocarcinoma classification: patterns and prognosis.
Kuhn E, Morbini P, Cancellieri A, Damiani S, Cavazza A, Comin CE
Pathologica 2018 Mar;110(1):5-11. PMID: 30259909
The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the Forthcoming Eighth Edition of the TNM Classification of Lung Cancer.
Travis WD, Asamura H, Bankier AA, Beasley MB, Detterbeck F, Flieder DB, Goo JM, MacMahon H, Naidich D, Nicholson AG, Powell CA, Prokop M, Rami-Porta R, Rusch V, van Schil P, Yatabe Y; International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee and Advisory Board Members
J Thorac Oncol 2016 Aug;11(8):1204-1223. Epub 2016 Apr 21 doi: 10.1016/j.jtho.2016.03.025. PMID: 27107787
Current readings: pathology, prognosis, and lung cancer.
Suh JH
Semin Thorac Cardiovasc Surg 2013 Spring;25(1):14-21. doi: 10.1053/j.semtcvs.2013.01.003. PMID: 23800525
Radiologic implications of the 2011 classification of adenocarcinoma of the lung.
Austin JH, Garg K, Aberle D, Yankelevitz D, Kuriyama K, Lee HJ, Brambilla E, Travis WD
Radiology 2013 Jan;266(1):62-71. Epub 2012 Oct 15 doi: 10.1148/radiol.12120240. PMID: 23070271
International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.
Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE, Garg K, Austin JH, Asamura H, Rusch VW, Hirsch FR, Scagliotti G, Mitsudomi T, Huber RM, Ishikawa Y, Jett J, Sanchez-Cespedes M, Sculier JP, Takahashi T, Tsuboi M, Vansteenkiste J, Wistuba I, Yang PC, Aberle D, Brambilla C, Flieder D, Franklin W, Gazdar A, Gould M, Hasleton P, Henderson D, Johnson B, Johnson D, Kerr K, Kuriyama K, Lee JS, Miller VA, Petersen I, Roggli V, Rosell R, Saijo N, Thunnissen E, Tsao M, Yankelewitz D
J Thorac Oncol 2011 Feb;6(2):244-85. doi: 10.1097/JTO.0b013e318206a221. PMID: 21252716Free PMC Article

Clinical prediction guides

Validation Study of New IASLC Histology Grading System in Stage I Non-Mucinous Adenocarcinoma Comparing With Minimally Invasive Adenocarcinoma.
Woo W, Cha YJ, Kim BJ, Moon DH, Lee S
Clin Lung Cancer 2022 Nov;23(7):e435-e442. Epub 2022 Jun 22 doi: 10.1016/j.cllc.2022.06.004. PMID: 35945128
Solid histological component of adenocarcinoma might play an important role in PD-L1 expression of lung adenocarcinoma.
Miyazawa T, Morikawa K, Otsubo K, Sakai H, Kimura H, Chosokabe M, Furuya N, Marushima H, Kojima K, Mineshita M, Koike J, Saji H
Thorac Cancer 2022 Jan;13(1):24-30. Epub 2021 Nov 23 doi: 10.1111/1759-7714.14209. PMID: 34811933Free PMC Article
The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the Forthcoming Eighth Edition of the TNM Classification of Lung Cancer.
Travis WD, Asamura H, Bankier AA, Beasley MB, Detterbeck F, Flieder DB, Goo JM, MacMahon H, Naidich D, Nicholson AG, Powell CA, Prokop M, Rami-Porta R, Rusch V, van Schil P, Yatabe Y; International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee and Advisory Board Members
J Thorac Oncol 2016 Aug;11(8):1204-1223. Epub 2016 Apr 21 doi: 10.1016/j.jtho.2016.03.025. PMID: 27107787
Current readings: pathology, prognosis, and lung cancer.
Suh JH
Semin Thorac Cardiovasc Surg 2013 Spring;25(1):14-21. doi: 10.1053/j.semtcvs.2013.01.003. PMID: 23800525
International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.
Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE, Garg K, Austin JH, Asamura H, Rusch VW, Hirsch FR, Scagliotti G, Mitsudomi T, Huber RM, Ishikawa Y, Jett J, Sanchez-Cespedes M, Sculier JP, Takahashi T, Tsuboi M, Vansteenkiste J, Wistuba I, Yang PC, Aberle D, Brambilla C, Flieder D, Franklin W, Gazdar A, Gould M, Hasleton P, Henderson D, Johnson B, Johnson D, Kerr K, Kuriyama K, Lee JS, Miller VA, Petersen I, Roggli V, Rosell R, Saijo N, Thunnissen E, Tsao M, Yankelewitz D
J Thorac Oncol 2011 Feb;6(2):244-85. doi: 10.1097/JTO.0b013e318206a221. PMID: 21252716Free PMC Article

Recent systematic reviews

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.
Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE, Garg K, Austin JH, Asamura H, Rusch VW, Hirsch FR, Scagliotti G, Mitsudomi T, Huber RM, Ishikawa Y, Jett J, Sanchez-Cespedes M, Sculier JP, Takahashi T, Tsuboi M, Vansteenkiste J, Wistuba I, Yang PC, Aberle D, Brambilla C, Flieder D, Franklin W, Gazdar A, Gould M, Hasleton P, Henderson D, Johnson B, Johnson D, Kerr K, Kuriyama K, Lee JS, Miller VA, Petersen I, Roggli V, Rosell R, Saijo N, Thunnissen E, Tsao M, Yankelewitz D
J Thorac Oncol 2011 Feb;6(2):244-85. doi: 10.1097/JTO.0b013e318206a221. PMID: 21252716Free PMC Article

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