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Malignant spiradenoma

MedGen UID:
266097
Concept ID:
C1266063
Neoplastic Process
Synonym: Malignant eccrine spiradenoma
SNOMED CT: Malignant eccrine spiradenoma (403942003); Malignant eccrine spiradenoma of skin (403942003); Malignant spiradenoma (403942003); Malignant eccrine spiradenoma (128895006)
 
Monarch Initiative: MONDO:0004412

Definition

A very rare, aggressive carcinoma of the sweat glands arising from malignant transformation of a long standing spiradenoma. It usually grows in the upper extremities, lower extremities, trunk, and head and neck. It has the tendency to recur and metastasize most often to the lymph nodes, bones, and lungs. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant spiradenoma

Professional guidelines

PubMed

Wagner K, Jassal K, Lee JC, Ban EJ, Cameron R, Serpell J
ANZ J Surg 2021 Oct;91(10):1996-2001. Epub 2021 Feb 1 doi: 10.1111/ans.16626. PMID: 33522696

Recent clinical studies

Etiology

Fernández-Aceñero MJ, Manzarbeitia F, Mestre de Juan MJ, Requena L
J Am Acad Dermatol 2001 Feb;44(2 Suppl):395-8. doi: 10.1067/mjd.2001.107471. PMID: 11174426

Diagnosis

Kibe Y, Tanahashi K, Ohtakara K, Okumura Y, Ohka F, Takeuchi K, Nagata Y, Motomura K, Akahori S, Mizuno A, Sasaki H, Shimizu H, Yamaguchi J, Nishikawa T, Yokota K, Saito R
BMC Neurol 2022 Jun 18;22(1):223. doi: 10.1186/s12883-022-02749-4. PMID: 35717180Free PMC Article
Wagner K, Jassal K, Lee JC, Ban EJ, Cameron R, Serpell J
ANZ J Surg 2021 Oct;91(10):1996-2001. Epub 2021 Feb 1 doi: 10.1111/ans.16626. PMID: 33522696
Kanwaljeet S, Chatterjee T
Indian J Cancer 2017 Oct-Dec;54(4):695-696. doi: 10.4103/ijc.IJC_301_17. PMID: 30082561
Emam EE, Sawan AS, Al-Tamimi SR, Molah RM
Saudi Med J 2012 Nov;33(11):1229-33. PMID: 23147883
Fernández-Aceñero MJ, Manzarbeitia F, Mestre de Juan MJ, Requena L
J Am Acad Dermatol 2001 Feb;44(2 Suppl):395-8. doi: 10.1067/mjd.2001.107471. PMID: 11174426

Prognosis

Le LP, Dias-Santagata D, Pawlak AC, Cosper AK, Nguyen AT, Selim MA, Deng A, Horick NK, Iafrate AJ, Mihm MC Jr, Hoang MP
PLoS One 2012;7(10):e47290. Epub 2012 Oct 9 doi: 10.1371/journal.pone.0047290. PMID: 23056620Free PMC Article
Fernández-Aceñero MJ, Manzarbeitia F, Mestre de Juan MJ, Requena L
J Am Acad Dermatol 2001 Feb;44(2 Suppl):395-8. doi: 10.1067/mjd.2001.107471. PMID: 11174426

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